Beta-arrestin-mediated localization of smoothened to the primary cilium - Wikidata - wikimedia - TriplyDB

Beta-arrestin-mediated localization of smoothened to the primary cilium

Beta-arrestin-mediated localization of smoothened to the primary cilium

http://www.wikidata.org/entity/Q36983577

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The Golgin GMAP210/TRIP11 anchors IFT20 to the Golgi complex The dynamic cilium in human diseases Increased expression of the dyslexia candidate gene DCDC2 affects length and signaling of primary cilia in neurons Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling DISC1 regulates primary cilia that display specific dopamine receptors The hedgehog receptor patched is involved in cholesterol transport GRK2: multiple roles beyond G protein-coupled receptor desensitization The primary cilium as a cellular signaling center: lessons from disease Ins and outs of GPCR signaling in primary cilia Aberrant activation of the hedgehog signaling pathway in malignant hematological neoplasms Decoding the phosphorylation code in Hedgehog signal transduction Recruitment of β-Arrestin into Neuronal Cilia Modulates Somatostatin Receptor Subtype 3 Ciliary Localization.Pitchfork and Gprasp2 Target Smoothened to the Primary Cilium for Hedgehog Pathway Activation Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesis Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened Mechanosensing by the primary cilium: deletion of Kif3A reduces bone formation due to loading Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved The vertebrate primary cilium in development, homeostasis, and disease Inositol hexakisphosphate kinase-2 acts as an effector of the vertebrate Hedgehog pathway.Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium.Recent patents for Hedgehog pathway inhibitors for the treatment of malignancy.Primary ciliogenesis defects are associated with human astrocytoma/glioblastoma cells.Opposite-polarity motors activate one another to trigger cargo transport in live cells Human Luteinizing Hormone and Chorionic Gonadotropin Display Biased Agonism at the LH and LH/CG Receptors Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function.Diverse cell type-specific mechanisms localize G protein-coupled receptors to Caenorhabditis elegans sensory cilia Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.Role of the Drosophila non-visual ß-arrestin kurtz in hedgehog signalling.Beyond desensitization: physiological relevance of arrestin-dependent signaling.Mechanism and evolution of cytosolic Hedgehog signal transduction DGKδ triggers endoplasmic reticulum release of IFT88-containing vesicles destined for the assembly of primary cilia.Rab23 is a flagellar protein in Trypanosoma brucei Teaching old receptors new tricks: biasing seven-transmembrane receptors.Simultaneous measurement of smoothened entry into and exit from the primary cilium.miR-326 is downstream of Sonic hedgehog signaling and regulates the expression of Gli2 and smoothened.Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila.Cilia in the CNS: the quiet organelle claims center stage

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P2860

Beta-arrestin-mediated localization of smoothened to the primary cilium

http://www.wikidata.org/entity/Q36983577

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Beta-arrestin-mediated localization of smoothened to the primary cilium

@en

type

label

Beta-arrestin-mediated localization of smoothened to the primary cilium

@en

prefLabel

Beta-arrestin-mediated localization of smoothened to the primary cilium

@en

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SCIENCE.1157983

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P1476

Beta-arrestin-mediated localization of smoothened to the primary cilium

@en

P2093

Erin J Whalen

http://www.w3.org/2001/XMLSchema#string

Jeffrey J Kovacs

http://www.w3.org/2001/XMLSchema#string

Jiangbo Wang

http://www.w3.org/2001/XMLSchema#string

Jihee Kim

http://www.w3.org/2001/XMLSchema#string

Kunhong Xiao

http://www.w3.org/2001/XMLSchema#string

Minyong Chen

http://www.w3.org/2001/XMLSchema#string

Renshui Liu

http://www.w3.org/2001/XMLSchema#string

Robert J Lefkowitz

http://www.w3.org/2001/XMLSchema#string

Wei Chen

http://www.w3.org/2001/XMLSchema#string

P2860

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

Functional specialization of beta-arrestin interactions revealed by proteomic analysis

Vertebrate Smoothened functions at the primary cilium.

Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates

Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2

Localization of 5-HT(6) receptors at the plasma membrane of neuronal cilia in the rat brain

Cilia and Hedgehog responsiveness in the mouse

Hedgehog signalling in the mouse requires intraflagellar transport proteins

Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli

Patched1 regulates hedgehog signaling at the primary cilium

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1777-1781

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scholarly article

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10.1126/SCIENCE.1157983

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P433

5884

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320

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2008-05-22T00:00:00Z

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5353539

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18497258

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2587210

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