Cytokines and beta-cell biology: from concept to clinical translation.
about
High glucose suppresses human islet insulin biosynthesis by inducing miR-133a leading to decreased polypyrimidine tract binding protein-expressionMicroRNAs: Novel Players in the Dialogue between Pancreatic Islets and Immune System in Autoimmune DiabetesThe central role of calcium in the effects of cytokines on beta-cell function: implications for type 1 and type 2 diabetesStem cell therapy for diabetes mellitusSilencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretionCEBPA exerts a specific and biologically important proapoptotic role in pancreatic β cells through its downstream network targetsIdentification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene ExpressionA novel fluorescence imaging approach for comparative measurements of pancreatic islet function in vitro.Evolution of β-Cell Replacement Therapy in Diabetes Mellitus: Islet Cell TransplantationResolving the conundrum of islet transplantation by linking metabolic dysregulation, inflammation, and immune regulation.Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic beta-cell function.Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protectionIslet endothelial activation and oxidative stress gene expression is reduced by IL-1Ra treatment in the type 2 diabetic GK ratGlycemic control promotes pancreatic beta-cell regeneration in streptozotocin-induced diabetic mice.A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control.Declining beta-cell compensation for insulin resistance in Hispanic women with recent gestational diabetes mellitus: association with changes in weight, adiponectin, and C-reactive protein.Defining and characterizing the progression of type 2 diabetes.Myt3 Mediates Laminin-V/Integrin-β1-Induced Islet-Cell Migration via TgfbiInvolvement of microRNAs in the cytotoxic effects exerted by proinflammatory cytokines on pancreatic beta-cells.Control of precursor maturation and disposal is an early regulative mechanism in the normal insulin production of pancreatic β-cells.CTSH regulates β-cell function and disease progression in newly diagnosed type 1 diabetes patients.Effects of rosiglitazone on inflammation in Otsuka long-evans Tokushima Fatty rats.Inhibition or deletion of soluble epoxide hydrolase prevents hyperglycemia, promotes insulin secretion, and reduces islet apoptosis.Possible role of interleukin-1β in type 2 diabetes onset and implications for anti-inflammatory therapy strategies.miR-296-3p, miR-298-5p and their downstream networks are causally involved in the higher resistance of mammalian pancreatic α cells to cytokine-induced apoptosis as compared to β cellsEnhancing pancreatic Beta-cell regeneration in vivo with pioglitazone and alogliptin.Stimulus-induced S-nitrosylation of Syntaxin 4 impacts insulin granule exocytosisSmall-molecule inhibition of inflammatory β-cell death.Histone deacetylase inhibitors for treating a spectrum of diseases not related to cancerEffect of diacerein on insulin secretion and metabolic control in drug-naive patients with type 2 diabetes: a randomized clinical trial.Huntingtin-interacting protein 14 is a type 1 diabetes candidate protein regulating insulin secretion and beta-cell apoptosisParasitic helminths and their beneficial impact on type 1 and type 2 diabetes.θ-Defensin RTD-1 improves insulin action and normalizes plasma glucose and FFA levels in diet-induced obese rats.Schizandra arisanensis extract attenuates cytokine-mediated cytotoxicity in insulin-secreting cells.Lysine 63-linked ubiquitination modulates mixed lineage kinase-3 interaction with JIP1 scaffold protein in cytokine-induced pancreatic β cell deathResveratrol prevents interleukin-1β-induced dysfunction of pancreatic β-cells.Glucolipotoxicity: fuel excess and beta-cell dysfunction.Interleukin-1 antagonists and other cytokine blockade strategies for type 1 diabetes.Phospho-BAD BH3 mimicry protects β cells and restores functional β cell mass in diabetes.IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat
P2860
Q21136357-0E52668E-B8D1-414C-9ACA-9693C3A86824Q26784462-70465F66-06CB-491B-8F61-AEF059FB56B8Q26860579-CE091A45-21C7-4B01-9AAC-869595D1CD01Q27011453-A14BD55A-CFEE-4B81-9615-E6C00A94B9C8Q28582459-19051ABA-001B-4085-AFAC-AF64BA379F27Q28654309-7EBA4E96-0194-41EE-A8CE-9A456EC84BC5Q30002303-E28F3FE2-F4B6-4B3C-A1FB-E7175242684FQ30429083-43BA954C-EB61-45B1-92AF-11C9987FEB8DQ30430239-65188C37-A7DD-4415-8916-B31FAAD8DBF6Q30437086-C3303E62-D3AE-4D93-BF69-B9116DB9DB67Q30500111-CE894C90-9268-47F8-B72C-D16790E53ABBQ32945672-000824AD-D4F4-4B82-BD93-39C8F04CCA20Q33501717-7006C128-E5D8-4F2C-B7A2-302410D9D90BQ33525549-9D2C69EF-69E8-438E-8C5C-1BBC555F746AQ33541007-E83C3F30-A79A-4162-A3FE-E67A465C0AB1Q33602322-6808497F-28FD-4706-B637-A3D4D1F41985Q33610728-9CEF523B-2B6E-42FA-8FE8-2BB694497D37Q33631551-D9493D6B-9755-4AB6-B86C-73D287AE081FQ33750755-498BE9EC-1804-40DD-B63A-5D178278205BQ33894918-389CC183-219D-4C31-85FD-86274A25342BQ33925780-51EAA7D2-6B19-42A2-9C20-5A772EC2E8A5Q33969599-58B4CDD8-92C0-4D80-AC4D-DFC26B154A51Q34035269-33780271-614A-474B-8E18-1E460936D0E5Q34104455-57EF271C-4B97-435F-A3C1-E04997B95971Q34566878-F1D62A11-C92D-42A3-99DF-63362F45710EQ34770205-F0B8CBA9-DFAE-4F14-862F-90878B8DB78CQ34963637-D8A3020D-0005-4106-81E4-459DAAAB633DQ34978002-A2FC3148-E26F-4617-86BA-6E6994A9AF14Q35016934-79897436-25DC-4FB3-AA89-DD6B86F5D7BBQ35060231-0F160C6F-E533-4B29-8077-A25169E438B6Q35217022-B188A0EF-5B1D-409D-A64A-A33DCB44F239Q35676595-47705952-3B8D-4D93-B152-74DF8D459CEEQ35859158-C83D1804-044F-4A55-ABCE-207FAEEA3D9AQ36461027-8AB41918-9120-4070-A849-D6B749D8B7A8Q36561985-43CD8972-8953-463D-BD80-6E9A327C1828Q36681917-DDFFAE9E-F09F-45B2-BCF0-6587F2A96828Q36861036-3D32BB1C-B6E4-4F44-8809-39CD1D69E1C5Q37088215-41C8D1E8-BB2C-4400-B852-35B1BEAC9C29Q37189580-ACC72273-8DE1-4FC2-BB2B-1A6D2FDF0E70Q37310711-B531C99C-02CC-48FE-99DB-B23C979C366E
P2860
Cytokines and beta-cell biology: from concept to clinical translation.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Cytokines and beta-cell biology: from concept to clinical translation.
@en
Cytokines and beta-cell biology: from concept to clinical translation.
@nl
type
label
Cytokines and beta-cell biology: from concept to clinical translation.
@en
Cytokines and beta-cell biology: from concept to clinical translation.
@nl
prefLabel
Cytokines and beta-cell biology: from concept to clinical translation.
@en
Cytokines and beta-cell biology: from concept to clinical translation.
@nl
P50
P356
P1433
P1476
Cytokines and beta-cell biology: from concept to clinical translation.
@en
P2093
Lukas A Berchtold
Marc Y Donath
P304
P356
10.1210/ER.2007-0033
P577
2007-11-29T00:00:00Z