A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer. - Wikidata - wikimedia - TriplyDB

A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer.

A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer.

http://www.wikidata.org/entity/Q38328518

about

Formation of VEGF isoform-specific spatial distributions governing angiogenesis: computational analysis Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88 Extracellular regulation of VEGF: isoforms, proteolysis, and vascular patterning.Mouse models for studying angiogenesis and lymphangiogenesis in cancer The role of tumor microenvironment in therapeutic resistance Characterization of molecular interactions between eosinophil cationic protein and heparin Mechanisms of heparanase inhibitors in cancer therapy.Conformational changes of 1-4-glucopyranosyl residues of a sulfated C-C linked hexasaccharide Genetic deletion of the desmosomal component desmoplakin promotes tumor microinvasion in a mouse model of pancreatic neuroendocrine carcinogenesis Versatile role of heparanase in inflammation Cancer and the tumor microenvironment: a review of an essential relationship.Elemene inhibits the migration and invasion of 4T1 murine breast cancer cells via heparanase.Adjuvant heparanase inhibitor PI-88 therapy for hepatocellular carcinoma recurrence Polymorphic genetic control of tumor invasion in a mouse model of pancreatic neuroendocrine carcinogenesis.Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis.Distinct roles for cysteine cathepsin genes in multistage tumorigenesis Anticancer drugs from marine flora: an overview.Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis.Interleukin-2 is present in human blood vessels and released in biologically active form by heparanase.Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis.Heparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetes.Distinct roles of vascular endothelial growth factor-D in lymphangiogenesis and metastasis.Heparan sulfate sulfatase SULF2 regulates PDGFRα signaling and growth in human and mouse malignant glioma The syndecan-1 heparan sulfate proteoglycan is a viable target for myeloma therapy.Novel therapeutic targets in the brain tumor microenvironment Significance of heparanase in cancer and inflammation.Genetic alteration of endothelial heparan sulfate selectively inhibits tumor angiogenesis Effect of Fraxiparine, a type of low molecular weight heparin, on the invasion and metastasis of lung adenocarcinoma A549 cells.Heparan sulfate mimetic PG545-mediated antilymphoma effects require TLR9-dependent NK cell activation Pharmacological inhibition of DNA methylation induces proinvasive and prometastatic genes in vitro and in vivo.Stromal biology of pancreatic cancer.Heparanase: a target for drug discovery in cancer and inflammation.Proteoglycans in cancer biology, tumour microenvironment and angiogenesis.Proteoglycans and their roles in brain cancer.Heparanase stimulation of protease expression implicates it as a master regulator of the aggressive tumor phenotype in myeloma Heparanase: one molecule with multiple functions in cancer progression.New pharmacological strategies against metastatic spread.Polyanionic drugs and viral oncogenesis: a novel approach to control infection, tumor-associated inflammation and angiogenesis.Induction of heparanase by HPV E6 oncogene in head and neck squamous cell carcinoma.Heparanase in inflammation and inflammation-associated cancer.

P2860

Q21202775-EA073890-2586-499A-9ECF-707912E45852 Q24328759-D915DAB0-7C61-4470-8B4E-3DB049E8E729 Q27000351-065DCFA2-B2A5-4615-9F5D-BC3A9C2E9C09 Q27003898-8D5BD945-1B2F-4FF2-8DE5-E4C062FB3DBC Q28069049-EE834F7F-70B8-465C-8CDC-7FCB068212C4 Q28285739-581A53B3-B6D7-489B-B083-6A08A4975F26 Q30244089-49C876E8-6A8B-4F6A-9E96-5D93216E70E1 Q33654719-380476E8-EC06-4D31-9741-CFD12261D153 Q33700543-CB71DB42-1DA7-4965-B642-726C27DCBFB4 Q33770777-CA04C7D5-6B99-423E-A57F-11CEE63F7963 Q33806357-1501387B-DCA6-404C-82BF-BE8F87B164A6 Q33828297-84449F6F-C3E8-488F-8D0F-8A2A53F3A0AF Q34093919-7AD358EC-0E02-4F5F-A060-CFE1ECCD5351 Q34182453-446440DF-1DAB-4B74-BDCB-8ABB08F128A4 Q34398151-A8163276-B92E-4403-A4B7-5DD798634F97 Q34471105-BE0B46E6-1566-4F07-98E6-37C53CCD0935 Q34726833-FFA6C58F-35A9-41FE-89E3-51497C2F5B90 Q34928194-5364045D-3E98-431F-B6A6-B00BB4BA1AF8 Q35181984-D3238DF4-D248-4CE0-8DDC-7A126C0F8C29 Q35224567-98A82AEB-0D36-48AA-821E-00904CBA861A Q35640553-30595D09-68E8-4E96-BF45-46F8364A53AA Q35691635-A994245B-7074-4464-ACEB-42820C09B594 Q35780214-22860283-3617-4F20-B705-801393E113F0 Q35990705-371FC4BA-9D5C-4667-B1CF-D19FF8900444 Q36071884-4BEA80C1-49FA-4A3D-AFCF-1D3C6AD150E5 Q36101233-A569530B-7E18-47ED-B8A9-3A6C28B6FADE Q36119681-A97C8F9C-6672-4105-B2A5-49644CEFBA90 Q36216588-C8119381-40B6-470A-A9BF-65F26B20514E Q36430711-79880903-C2D8-4FA0-B041-310B33965002 Q36485293-0CC050A7-5E82-4FC1-BFEA-9ABF91397BDC Q36723725-6AD6D9E1-DBFD-4748-8EE5-49BCA439E55C Q36752653-A7653359-A845-482B-945A-F8DF2F9B2F8F Q36787608-9AB74D4D-ED2F-4029-8D3A-E044111007C3 Q36816444-AF6B9732-A42F-44D5-B662-A2869C8B180A Q36973696-59854605-90E9-4816-A3E9-B2DC3FD98B0C Q37228578-CA7F3805-61D4-4F11-B480-91F0CDF5ABA0 Q37290200-36D79F13-8A37-4E7B-BF0C-D950F66C885A Q37323266-EED07ED9-533A-4F27-BB54-C7196D4E13AD Q37562372-F44244DA-B19E-4982-BCBD-4BFF34F0FE8E Q38080632-A4D45621-829E-4012-957F-E45060600468

P2860

A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer.

http://www.wikidata.org/entity/Q38328518

description

2005 nî lūn-bûn

@nan

2005年の論文

@ja

2005年学术文章

@wuu

2005年学术文章

@zh-cn

2005年学术文章

@zh-hans

2005年学术文章

@zh-my

2005年学术文章

@zh-sg

2005年學術文章

@yue

2005年學術文章

@zh

2005年學術文章

@zh-hant

name

A functional heparan sulfate m ...... se model of multistage cancer.

@en

type

label

A functional heparan sulfate m ...... se model of multistage cancer.

@en

prefLabel

A functional heparan sulfate m ...... se model of multistage cancer.

@en

P1433

Q38328518-841DD46B-77D2-49FC-A271-6634FBB62191

P1476

Q38328518-7C4FA2EE-6244-432F-A39F-43EE8507DE70

P2093

Q38328518-1CA745C6-B839-4429-917C-FD07EA9001C4

Q38328518-52319DF0-DF6A-44AA-BFE3-EE77250536AE

Q38328518-65454D87-4652-4E76-90F2-2187AE07FA48

Q38328518-94980C76-9059-4C30-9DD7-5476AC789213

Q38328518-99206131-C19E-48F1-B4A3-CC29773F153F

P2860

Q38328518-2066C1D2-8FE7-4DC2-936A-865F78F8CCF7

Q38328518-2931114F-A507-4DC7-B8C1-09A1FA087AEF

Q38328518-3DD8853C-FFAC-4E5C-A8A8-E92E25FE7D50

Q38328518-47ED2211-DC15-4C35-95DE-E25E656FECAC

Q38328518-4CB9D2C1-B17D-4EA5-8E78-763CF54B0A78

Q38328518-550FA89D-37C6-45FD-9713-B9B06E7E2621

Q38328518-591955DC-6950-46B0-BDF0-93B4EE93C80E

Q38328518-59DB3C0F-F74E-4697-B6DF-8FA8BD5AC702

Q38328518-80F73ACD-696C-4312-BEAA-9C19EC73953C

Q38328518-95E0658A-243C-4DFD-AEDC-1F88BAACA993

P2888

Q38328518-A5230A5B-BDC6-4163-8E57-6422AC0ECDA4

P304

Q38328518-5CC16273-C09B-433A-84F2-071A0B1E0BF6

P31

Q38328518-18C5F7A0-41CD-4405-94CB-AB4BDB614B4A

P356

Q38328518-EB28EF8D-7D1C-46CD-B17C-8C827B375764

P407

Q38328518-25D0D3A5-EF89-4FD2-9AEB-ADAED7223BCA

P433

Q38328518-1A2558D4-162C-462D-B173-6D286865B97A

P478

Q38328518-9B569741-930A-49B4-8194-33E67238951A

P577

Q38328518-8557A1FE-9449-45CF-94C7-1DF5B79F1FBB

P5875

Q38328518-D407D90C-C547-459B-9EE6-9AC0A5BFD2D0

P6179

Q38328518-147F0CF8-2826-4A0E-9AFE-AF940D9A67A7

P698

Q38328518-168E7EFE-C528-4AA6-85D2-0F9488AA8468

P356

P1433

P1476

A functional heparan sulfate m ...... se model of multistage cancer.

@en

P2093

Christopher R Parish

http://www.w3.org/2001/XMLSchema#string

Craig Freeman

http://www.w3.org/2001/XMLSchema#string

Douglas Hanahan

http://www.w3.org/2001/XMLSchema#string

Johanna A Joyce

http://www.w3.org/2001/XMLSchema#string

Nicole Meyer-Morse

http://www.w3.org/2001/XMLSchema#string

P2860

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

Fibroblast growth factors, their receptors and signaling

Heparanases and tumor metastasis

Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions

Functions of cell surface heparan sulfate proteoglycans

Probing the interactions of phosphosulfomannans with angiogenic growth factors by surface plasmon resonance.

Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene.

Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor.

Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis

Heparan sulfate proteoglycans: heavy hitters in the angiogenesis arena

P2888

P304

4037-4051

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1208602

http://www.w3.org/2001/XMLSchema#string

P407

P433

25

http://www.w3.org/2001/XMLSchema#string

P478

24

http://www.w3.org/2001/XMLSchema#string

P577

2005-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7930342

http://www.w3.org/2001/XMLSchema#string

P6179

1001380833

http://www.w3.org/2001/XMLSchema#string

P698

15806157

http://www.w3.org/2001/XMLSchema#string