mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization.
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Dopamine responsiveness is regulated by targeted sorting of D2 receptors.Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioidsNeurokinin 1 receptors regulate morphine-induced endocytosis and desensitization of mu-opioid receptors in CNS neuronsEngineered G protein coupled receptors reveal independent regulation of internalization, desensitization and acute signalingCannabinoid and opioid interactions: implications for opiate dependence and withdrawalCell-autonomous regulation of Mu-opioid receptor recycling by substance P.Mu-opioid receptor redistribution in the locus coeruleus upon precipitation of withdrawal in opiate-dependent ratsmicro-Opioid receptor endocytosis prevents adaptations in ventral tegmental area GABA transmission induced during naloxone-precipitated morphine withdrawal.How to design an opioid drug that causes reduced tolerance and dependence.The opioid system and brain development: effects of methadone on the oligodendrocyte lineage and the early stages of myelination.Tolerance to the antinociceptive effect of morphine in the absence of short-term presynaptic desensitization in rat periaqueductal gray neuronsMorphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence.Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: from a symposium on new concepts in mu-opioid pharmacologyMorphine induces μ opioid receptor endocytosis in guinea pig enteric neurons following prolonged receptor activationFunctional selectivity and time-dependence of μ-opioid receptor desensitization at nerve terminals in the mouse ventral tegmental areaChange in functional selectivity of morphine with the development of antinociceptive tolerance.Heteromerization of the μ- and δ-opioid receptors produces ligand-biased antagonism and alters μ-receptor traffickingDifferential activation and trafficking of micro-opioid receptors in brain slices.Agonist-directed interactions with specific beta-arrestins determine mu-opioid receptor trafficking, ubiquitination, and dephosphorylation.Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.Analysis of opioid efficacy, tolerance, addiction and dependence from cell culture to humanOpioid receptor internalization contributes to dermorphin-mediated antinociceptionRole of G Protein-Coupled Receptor Kinases 2 and 3 in μ-Opioid Receptor Desensitization and InternalizationDistinct effects of individual opioids on the morphology of spines depend upon the internalization of mu opioid receptorsMu-opioid receptor desensitization: is morphine different?Effects of chronic opioid exposure on guinea pig mu opioid receptor in Chinese hamster ovary cells: comparison with human and rat receptorAnalgesic tolerance to microinjection of the micro-opioid agonist DAMGO into the ventrolateral periaqueductal gray.Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.Morphine desensitization and cellular tolerance are distinguished in rat locus ceruleus neurons.μ-Opioid receptor desensitization: homologous or heterologous?Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Post-activation-mediated changes in opioid receptors detected by N-terminal antibodies.Ligand-induced μ opioid receptor internalization in enteric neurons following chronic treatment with the opiate fentanylChronic morphine treatment reduces recovery from opioid desensitization.Agonist-specific regulation of mu-opioid receptor desensitization and recovery from desensitizationMorphine-induced mu-opioid receptor rapid desensitization is independent of receptor phosphorylation and beta-arrestinsEthanol reversal of cellular tolerance to morphine in rat locus coeruleus neuronsMolecular Pharmacology of δ-Opioid Receptors.Functional characterization of human variants of the mu-opioid receptor geneBidirectional effects of fentanyl on dendritic spines and AMPA receptors depend upon the internalization of mu opioid receptors
P2860
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P2860
mu-Opioid receptors: Ligand-dependent activation of potassium conductance, desensitization, and internalization.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
mu-Opioid receptors: Ligand-de ...... tization, and internalization.
@en
type
label
mu-Opioid receptors: Ligand-de ...... tization, and internalization.
@en
prefLabel
mu-Opioid receptors: Ligand-de ...... tization, and internalization.
@en
P2093
P1476
mu-Opioid receptors: Ligand-de ...... itization, and internalization
@en
P2093
Abdallah Salem
David K Grandy
Jennifer L Whistler
John T Williams
Mark Von Zastrow
Seksiri Arttamangkul
P304
P356
10.1523/JNEUROSCI.22-13-05769.2002
P407
P577
2002-07-01T00:00:00Z