Role of p300, a transcriptional coactivator, in signalling of TGF-beta. - Wikidata - wikimedia - TriplyDB

Role of p300, a transcriptional coactivator, in signalling of TGF-beta.

Role of p300, a transcriptional coactivator, in signalling of TGF-beta.

http://www.wikidata.org/entity/Q40835770

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Smad proteins function as co-modulators for MEF2 transcriptional regulatory proteins Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads Menin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2 Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins The Smad3 linker region contains a transcriptional activation domain A novel smad nuclear interacting protein, SNIP1, suppresses p300-dependent TGF-beta signal transduction Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3)Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins Targeting TGF-β signaling in cancer Sp1 and Smad proteins cooperate to mediate transforming growth factor-beta 1-induced alpha 2(I) collagen expression in human glomerular mesangial cells Regulation of transforming growth factor-beta signaling by protein inhibitor of activated STAT, PIASy through Smad3 Two short segments of Smad3 are important for specific interaction of Smad3 with c-Ski and SnoN SNIP1 inhibits NF-kappa B signaling by competing for its binding to the C/H1 domain of CBP/p300 transcriptional co-activators Intracellular signaling of the TGF-beta superfamily by Smad proteins.Characterization of a bone morphogenetic protein-responsive Smad-binding element.Two major Smad pathways in TGF-beta superfamily signalling.TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth Activation of estrogen receptor-alpha reduces aortic smooth muscle differentiation Aortic Remodelling Is Improved by 2,3,5,4'-Tetrahydroxystilbene-2-O-β-D-glucoside Involving the Smad3 Pathway in Spontaneously Hypertensive Rats.Inhibition of E-selectin gene expression by transforming growth factor beta in endothelial cells involves coactivator integration of Smad and nuclear factor kappaB-mediated signals.Smad-dependent recruitment of a histone deacetylase/Sin3A complex modulates the bone morphogenetic protein-dependent transcriptional repressor activity of Nkx3.2.To (TGF)beta or not to (TGF)beta: fine-tuning of Smad signaling via post-translational modifications Trichostatin A, a histone deacetylase inhibitor suppresses NADPH Oxidase 4-Derived Redox Signalling and Angiogenesis The ERK-ZEB1 pathway mediates epithelial-mesenchymal transition in pemetrexed resistant lung cancer cells with suppression by vinca alkaloids.Transforming growth factor-beta signaling in epithelial-mesenchymal transition and progression of cancer.Epithelial-mesenchymal Transition and Cell Invasion.Autoregulation of Xvent-2B; direct interaction and functional cooperation of Xvent-2 and Smad1.An essential role for Mad homology domain 1 in the association of Smad3 with histone deacetylase activity*.Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.The transcriptional co-activator P/CAF potentiates TGF-beta/Smad signaling.Cyclic AMP enhances Smad-mediated BMP signaling through PKA-CREB pathway.The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation.Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta.Roles for lysine residues of the MH2 domain of Smad3 in transforming growth factor-beta signaling.Notch1 oncoprotein antagonizes TGF-beta/Smad-mediated cell growth suppression via sequestration of coactivator p300.c-myc is a downstream target of the Smad pathway.Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis.Targets of transcriptional regulation by transforming growth factor-beta: expression profile analysis using oligonucleotide arrays.Region between alpha-helices 3 and 4 of the mad homology 2 domain of Smad4: functional roles in oligomer formation and transcriptional activation.

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Role of p300, a transcriptional coactivator, in signalling of TGF-beta.

http://www.wikidata.org/entity/Q40835770

description

1998 nî lūn-bûn

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1998年の論文

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1998年学术文章

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1998年学术文章

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1998年学术文章

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1998年学术文章

@zh-my

1998年学术文章

@zh-sg

1998年學術文章

@yue

1998年學術文章

@zh

1998年學術文章

@zh-hant

name

Role of p300, a transcriptional coactivator, in signalling of TGF-beta.

@en

type

label

Role of p300, a transcriptional coactivator, in signalling of TGF-beta.

@en

prefLabel

Role of p300, a transcriptional coactivator, in signalling of TGF-beta.

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J.1365-2443.1998.00217.X

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Role of p300, a transcriptional coactivator, in signalling of TGF-beta.

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Hanai JI

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Kato S

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Kawabata M

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Miyazono K

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Nishihara A

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Okamoto N

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Yanagisawa J

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P2860

Synergistic activation of transcription by CBP and p53

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

Smad4 and FAST-1 in the assembly of activin-responsive factor

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

Phosphorylated CREB binds specifically to the nuclear protein CBP

Interaction of the transforming growth factor-beta type I receptor with farnesyl-protein transferase-alpha

Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene.

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10.1046/J.1365-2443.1998.00217.X

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9813111

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