Insulin mediates glucose-stimulated phosphorylation of PHAS-I by pancreatic beta cells. An insulin-receptor mechanism for autoregulation of protein synthesis by translation.
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Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells.Insulin receptor substrate 1 regulation of sarco-endoplasmic reticulum calcium ATPase 3 in insulin-secreting beta-cellsIdentifying the links between obesity, insulin resistance and beta-cell function: potential role of adipocyte-derived cytokines in the pathogenesis of type 2 diabetesGlucose exerts a permissive effect on the regulation of the initiation factor 4E binding protein 4E-BP1Polypyrimidine tract-binding protein promotes insulin secretory granule biogenesisAmino-acid-dependent signal transduction.Insulin receptor (IR) and insulin-like growth factor receptor 1 (IGF-1R) signaling systems: novel treatment strategies for cancer.Regulation of cellular growth by the Drosophila target of rapamycin dTORPancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation.A small molecule differentiation inducer increases insulin production by pancreatic β cellsExpression profiling of pancreatic beta cells: glucose regulation of secretory and metabolic pathway genesPlasticity of the beta cell insulin secretory competence: preparing the pancreatic beta cell for the next meal.Differential Regulation of ERK1/2 and mTORC1 Through T1R1/T1R3 in MIN6 CellsmTORC1 signaling and regulation of pancreatic β-cell mass.Molecular mechanism and regulation of autophagy.Metabotropic glutamate receptor-initiated translocation of protein kinase p90rsk to polyribosomes: a possible factor regulating synaptic protein synthesis.The unfolded protein response: a pathway that links insulin demand with beta-cell failure and diabetesPhosphorylation and degradation of S6K1 (p70S6K1) in response to persistent JNK1 Activation.Therapeutic Strategies to Increase Human β-Cell Growth and Proliferation by Regulating mTOR and GSK-3/β-Catenin Pathways.The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic β-cell mass: implications in the development of type-2 diabetes.Beta Cell Function and the Nutritional State: Dietary Factors that Influence Insulin Secretion.Hypothalamic Insulin Resistance in Obesity: Effects on Glucose Homeostasis.4E-BP2/SH2B1/IRS2 Are Part of a Novel Feedback Loop That Controls β-Cell Mass.The selective recruitment of mRNA to the ER and an increase in initiation are important for glucose-stimulated proinsulin synthesis in pancreatic beta-cells.The role of AMPK and mTOR in nutrient sensing in pancreatic beta-cells.Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha.Glucose regulates EF-2 phosphorylation and protein translation by a protein phosphatase-2A-dependent mechanism in INS-1-derived 832/13 cells.Structural requirement of leucine for activation of p70 S6 kinase.Glucose and amino acids modulate translation factor activation by growth factors in PC12 cells.Amino acid availability regulates p70 S6 kinase and multiple translation factors.Insulin receptor activation inhibits insulin secretion from human islets of Langerhans.Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.Nutrients differentially regulate multiple translation factors and their control by insulin.Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation.Leucine is a direct-acting nutrient signal that regulates protein synthesis in adipose tissue.Autocrine regulation of glucose metabolism in pancreatic islets.
P2860
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P2860
Insulin mediates glucose-stimulated phosphorylation of PHAS-I by pancreatic beta cells. An insulin-receptor mechanism for autoregulation of protein synthesis by translation.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Insulin mediates glucose-stimu ...... tein synthesis by translation.
@en
type
label
Insulin mediates glucose-stimu ...... tein synthesis by translation.
@en
prefLabel
Insulin mediates glucose-stimu ...... tein synthesis by translation.
@en
P2093
P2860
P921
P356
P1476
Insulin mediates glucose-stimu ...... tein synthesis by translation.
@en
P2093
Lawrence JC Jr
Marshall CA
McDaniel ML
Munivenkatappa RB
P2860
P304
P356
10.1074/JBC.273.8.4485
P407
P577
1998-02-01T00:00:00Z