High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.
about
P1343
The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulationOptimal functional levels of activation-induced deaminase specifically require the Hsp40 DnaJa1Genome instability and transcription elongation impairment in human cells depleted of THO/TREXSelective inhibition of class switching to IgG and IgE by recruitment of the HoxC4 and Oct-1 homeodomain proteins and Ku70/Ku86 to newly identified ATTT cis-elementsThe splicing regulator PTBP2 interacts with the cytidine deaminase AID and promotes binding of AID to switch-region DNAThe histone methyltransferase MMSET regulates class switch recombinationThe RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombinationThe AID antibody diversification enzyme is regulated by protein kinase A phosphorylation.Further Characterization of Activin A-induced IgA Response in Murine B Lymphocytes.Could the airway epithelium play an important role in mucosal immunoglobulin A production?Binding of AID to DNA does not correlate with mutator activity.A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs.Variable deletion and duplication at recombination junction ends: implication for staggered double-strand cleavage in class-switch recombinationWidespread genomic breaks generated by activation-induced cytidine deaminase are prevented by homologous recombination.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.Negative supercoiling creates single-stranded patches of DNA that are substrates for AID-mediated mutagenesis.PKA-mediated phosphorylation regulates the function of activation-induced deaminase (AID) in B cellsThe DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombinationLinking class-switch recombination with somatic hypermutation.Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90.Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination.Innate signaling networks in mucosal IgA class switchingIsolation of differentially expressed genes upon immunoglobulin class switching by a subtractive hybridization method using uracil DNA glycosylase.The regulation of IgA class switching.SUMO Proteins are not Involved in TGF-β1-induced, Smad3/4-mediated Germline α Transcription, but PIASy Suppresses it in CH12F3-2A B CellsIL-21 ensures TGF-beta 1-induced IgA isotype expression in mouse Peyer's patches.Clustered DNA lesion repair in eukaryotes: relevance to mutagenesis and cell survivalAID to overcome the limitations of genomic information by introducing somatic DNA alterations.Overlapping activation-induced cytidine deaminase hotspot motifs in Ig class-switch recombination.Generation and characterization of induced pluripotent stem cells from Aid-deficient mice.Genomic uracil homeostasis during normal B cell maturation and loss of this balance during B cell cancer development.Splice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells.TGF-β suppression of HBV RNA through AID-dependent recruitment of an RNA exosome complex.Complexities due to single-stranded RNA during antibody detection of genomic rna:dna hybrids.Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.Imbalanced PTEN and PI3K Signaling Impairs Class Switch Recombination.CSReport: A New Computational Tool Designed for Automatic Analysis of Class Switch Recombination Junctions Sequenced by High-Throughput Sequencing.Evidence for class-specific factors in immunoglobulin isotype switchingQuantitative regulation of class switch recombination by switch region transcription.
P2860
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P2860
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.
@en
type
label
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.
@en
prefLabel
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells.
@en
P2093
P356
P1476
High frequency class switching of an IgM+ B lymphoma clone CH12F3 to IgA+ cells
@en
P2093
P304
P356
10.1093/INTIMM/8.2.193
P4510
P577
1996-02-01T00:00:00Z