The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras.
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CD80 and CD86 are not equivalent in their ability to induce the tyrosine phosphorylation of CD28p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulationGrowth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signalingRegulatory and signaling properties of the Vav familyCell Type-Specific Regulation of Immunological Synapse Dynamics by B7 Ligand RecognitionSignal transduction by CD28 costimulatory receptor on T cells. B7-1 and B7-2 regulation of tyrosine kinase adaptor moleculesTwo distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase associationGrb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interactionThe role of Tec protein-tyrosine kinase in T cell signalingCD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axisEvidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cellsDeficiency of small GTPase Rac2 affects T cell activationTyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcriptionPhysical and functional interaction of Nef with Lck. HIV-1 Nef-induced T-cell signaling defects.Single-cell analysis of signal transduction in CD4 T cells stimulated by antigen in vivoSimian immunodeficiency virus Nef protein delays the progression of CD4+ T cells through G1/S phase of the cell cycle.T-cell tolerance and autoimmune diabetes.The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathwaysCD28 signals through acidic sphingomyelinase.RelA is a potent transcriptional activator of the CD28 response element within the interleukin 2 promoter.Human neonatal naive CD4+ T cells have enhanced activation-dependent signaling regulated by the microRNA miR-181a.Artificial antigen-presenting cells for use in adoptive immunotherapy.CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.Pleiotropic defects in TCR signaling in a Vav-1-null Jurkat T-cell line.Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen.IL-2 gene expression and NF-kappa B activation through CD28 requires reactive oxygen production by 5-lipoxygenaseCD28: a signalling perspective.Functional LCK Is required for optimal CD28-mediated activation of the TEC family tyrosine kinase EMT/ITK.The role of B7-1/B7-2:CD28/CLTA-4 pathways in the prevention of anergy, induction of productive immunity and down-regulation of the immune response.Cytotoxic T lymphocyte antigen 4 (CTLA-4) interferes with extracellular signal-regulated kinase (ERK) and Jun NH2-terminal kinase (JNK) activation, but does not affect phosphorylation of T cell receptor zeta and ZAP70.Evidence that a kinase distinct from protein kinase C and phosphatidylinositol 3-kinase mediates ligation-dependent serine/threonine phosphorylation of the T-lymphocyte co-stimulatory molecule CD28.Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cells. Evidence for the importance of Ras in a pathway that is controlled byAntiviral effect and ex vivo CD4+ T cell proliferation in HIV-positive patients as a result of CD28 costimulation.CD28 affects the earliest signaling events generated by TCR engagement.
P2860
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P2860
The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
The role of p21ras in CD28 sig ...... ligand B7-1, activates p21ras.
@en
The role of p21ras in CD28 sig ...... ligand B7-1, activates p21ras.
@nl
type
label
The role of p21ras in CD28 sig ...... ligand B7-1, activates p21ras.
@en
The role of p21ras in CD28 sig ...... ligand B7-1, activates p21ras.
@nl
prefLabel
The role of p21ras in CD28 sig ...... ligand B7-1, activates p21ras.
@en
The role of p21ras in CD28 sig ...... ligand B7-1, activates p21ras.
@nl
P2093
P2860
P356
P1476
The role of p21ras in CD28 sig ...... ligand B7-1, activates p21ras.
@en
P2093
P2860
P304
P356
10.1084/JEM.180.3.1067
P407
P577
1994-09-01T00:00:00Z