Ras-dependent, Ca2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells.
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Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domainSerine phosphorylation of Cbl induced by phorbol ester enhances its association with 14-3-3 proteins in T cells via a novel serine-rich 14-3-3-binding motifAPS facilitates c-Cbl tyrosine phosphorylation and GLUT4 translocation in response to insulin in 3T3-L1 adipocytescbl-b inhibits epidermal growth factor receptor signalingProtein kinase C mu is negatively regulated by 14-3-3 signal transduction proteinsRegulation of Cbl molecular interactions by the co-receptor molecule CD43 in human T cellsc-Cbl facilitates fibronectin matrix production by v-Abl-transformed NIH3T3 cells via activation of small GTPasesInterleukin-2 stimulation induces tyrosine phosphorylation of p120-Cbl and CrkL and formation of multimolecular signaling complexes in T lymphocytes and natural killer cellsCoordinated regulation of the tyrosine phosphorylation of Cbl by Fyn and Syk tyrosine kinasesThe CBL-related protein CBLB participates in FLT3 and interleukin-7 receptor signal transduction in pro-B cellsFyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cellsT cell activation induces direct binding of the Crk adapter protein to the regulatory subunit of phosphatidylinositol 3-kinase (p85) via a complex mechanism involving the Cbl protein.Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient miceThe oncogenic 70Z Cbl mutation blocks the phosphotyrosine binding domain-dependent negative regulation of ZAP-70 by c-Cbl in Jurkat T cells.Vav-Rac1-mediated activation of the c-Jun N-terminal kinase/c-Jun/AP-1 pathway plays a major role in stimulation of the distal NFAT site in the interleukin-2 gene promoterCbl: many adaptations to regulate protein tyrosine kinases.Beyond the RING: CBL proteins as multivalent adapters.The Tpl-2 protooncoprotein activates the nuclear factor of activated T cells and induces interleukin 2 expression in T cell lines.Cbl-family proteins as regulators of cytoskeleton-dependent phenomena.CBL linker region and RING finger mutations lead to enhanced granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling via elevated levels of JAK2 and LYN.Protein kinase C-associated kinase (PKK) mediates Bcl10-independent NF-kappa B activation induced by phorbol ester.Role of phosphoinositide 3-kinase and the Cbl adaptor protein in coupling the alpha4beta1 integrin to mitogen-activated protein kinase signalling.Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts.Cbl-mediated regulation of T cell receptor-induced AP1 activation. Implications for activation via the Ras signaling pathway.Regulation of protein kinase Ctheta function during T cell activation by Lck-mediated tyrosine phosphorylation.The roles of Cbl-b and c-Cbl in insulin-stimulated glucose transport.Involvement of phosphatidylinositol 3-kinase in NFAT activation in T cells.Dual regulation of T cell receptor-mediated signaling by oncogenic Cbl mutant 70Z.Activation of nuclear factor of activated T cells-(NFAT) and activating protein 1 (AP-1) by oncogenic 70Z Cbl requires an intact phosphotyrosine binding domain but not Crk(L) or p85 phosphatidylinositol 3-kinase association.Differential effects of Cbl and 70Z/3 Cbl on T cell receptor-induced phospholipase Cgamma-1 activity.Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain.The RING Finger Domain of Cbl Is Essential for Negative Regulation of the Syk Tyrosine Kinase
P2860
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P2860
Ras-dependent, Ca2+-stimulated activation of nuclear factor of activated T cells by a constitutively active Cbl mutant in T cells.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Ras-dependent, Ca2+-stimulated ...... active Cbl mutant in T cells.
@en
Ras-dependent, Ca2+-stimulated ...... active Cbl mutant in T cells.
@nl
type
label
Ras-dependent, Ca2+-stimulated ...... active Cbl mutant in T cells.
@en
Ras-dependent, Ca2+-stimulated ...... active Cbl mutant in T cells.
@nl
prefLabel
Ras-dependent, Ca2+-stimulated ...... active Cbl mutant in T cells.
@en
Ras-dependent, Ca2+-stimulated ...... active Cbl mutant in T cells.
@nl
P2093
P2860
P356
P1476
Ras-dependent, Ca2+-stimulated ...... y active Cbl mutant in T cells
@en
P2093
P2860
P304
P356
10.1074/JBC.272.1.168
P407
P50
P577
1997-01-01T00:00:00Z