A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells. - Wikidata - wikimedia - TriplyDB

A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells.

A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells.

http://www.wikidata.org/entity/Q43239185

about

Regulation of glucose homeostasis by GLP-1 Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons Mechanisms of action of glucagon-like peptide 1 in the pancreas GLP-1 receptor activated insulin secretion from pancreatic β-cells: mechanism and glucose dependence Cyclic AMP dynamics in the pancreatic β-cell cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells.Cell physiology of cAMP sensor Epac.Role of the cAMP sensor Epac as a determinant of KATP channel ATP sensitivity in human pancreatic beta-cells and rat INS-1 cells Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels The Concise Guide to PHARMACOLOGY 2013/14: enzymes.cAMP potentiates InsP3-induced Ca2+ release from the endoplasmic reticulum in blowfly salivary glands.PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.GLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activation Small G proteins in islet beta-cell function.Pancreatic beta cells synthesize neuropeptide Y and can rapidly release peptide co-transmitters Cyclic AMP-dependent protein kinase and Epac mediate cyclic AMP responses in pancreatic acini.Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1.High-throughput identification of IMCD proteins using LC-MS/MS Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors.Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.Phospholipase C-ε links Epac2 activation to the potentiation of glucose-stimulated insulin secretion from mouse islets of Langerhans Simvastatin Impairs Insulin Secretion by Multiple Mechanisms in MIN6 Cells.Role of phospholipase Cε in physiological phosphoinositide signaling networks.Bursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.Monitoring of cAMP synthesis and degradation in living cells.Sequential and compartmentalized action of Rabs, SNAREs, and MAL in the apical delivery of fusiform vesicles in urothelial umbrella cells Modeling analysis of inositol 1,4,5-trisphosphate receptor-mediated Ca2+ mobilization under the control of glucagon-like peptide-1 in mouse pancreatic β-cells.Pancreatic β-cell response to increased metabolic demand and to pharmacologic secretagogues requires EPAC2A Small G proteins as key regulators of pancreatic digestive enzyme secretion.Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells.Epac activates the small G proteins Rap1 and Rab3A to achieve exocytosis EPAC proteins transduce diverse cellular actions of cAMP.Cav1.2 and Cav1.3 are differentially coupled to glucagon-like peptide-1 potentiation of glucose-stimulated insulin secretion in the pancreatic beta-cell line INS-1.Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes.Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells.Glucagon-like peptide-1: modulator of β-cell dysfunction and death.New insights concerning the molecular basis for defective glucoregulation in soluble adenylyl cyclase knockout mice The proteins of exocytosis: lessons from the sperm model.The action of prostaglandins on ion channels.cAMP signalling in insulin and glucagon secretion.

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A cAMP and Ca2+ coincidence detector in support of Ca2+-induced Ca2+ release in mouse pancreatic beta cells.

http://www.wikidata.org/entity/Q43239185

description

2005 nî lūn-bûn

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2005年の論文

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年学术文章

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2005年學術文章

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2005年學術文章

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name

A cAMP and Ca2+ coincidence de ...... n mouse pancreatic beta cells.

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A cAMP and Ca2+ coincidence de ...... n mouse pancreatic beta cells.

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type

label

A cAMP and Ca2+ coincidence de ...... n mouse pancreatic beta cells.

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A cAMP and Ca2+ coincidence de ...... n mouse pancreatic beta cells.

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A cAMP and Ca2+ coincidence de ...... n mouse pancreatic beta cells.

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JPHYSIOL.2005.087510

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The Journal of Physiology

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A cAMP and Ca2+ coincidence de ...... n mouse pancreatic beta cells.

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P2093

George G Holz

http://www.w3.org/2001/XMLSchema#string

Guoxin Kang

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Leon Collis

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Mark Harbeck

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Michael J Rindler

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Michael W Roe

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Oleg G Chepurny

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Wen-Hong Li

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Zina Chepurny

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P2860

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts

RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets

Nuclear KATP channels trigger nuclear Ca(2+) transients that modulate nuclear function.

Glucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cells

Nicotinic acid-adenine dinucleotide phosphate-sensitive calcium stores initiate insulin signaling in human beta cells.

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

Epac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cell

Reducing the environmental sensitivity of yellow fluorescent protein. Mechanism and applications

A new generation of Ca2+ indicators with greatly improved fluorescence properties

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Pt 1

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