Cleavage of model replication forks by fission yeast Mus81-Eme1 and budding yeast Mus81-Mms4.
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Crystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substratesIdentification and characterization of human MUS81-MMS4 structure-specific endonucleaseWRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication forkMus81 endonuclease localizes to nucleoli and to regions of DNA damage in human S-phase cellsRNA interference inhibition of Mus81 reduces mitotic recombination in human cellsEme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cellsMus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiaeEvidence that the S.cerevisiae Sgs1 protein facilitates recombinational repair of telomeres during senescence.Nucleases in homologous recombination as targets for cancer therapyCrystal structure of the Mus81-Eme1 complexMus81 cleavage of Holliday junctions: a failsafe for processing meiotic recombination intermediates?Cooperativity of Mus81.Mms4 with Rad54 in the resolution of recombination and replication intermediates.Srs2 promotes Mus81-Mms4-mediated resolution of recombination intermediates.Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates.Replication checkpoint kinase Cds1 regulates Mus81 to preserve genome integrity during replication stress.The multifunctional SNM1 gene family: not just nucleasesProcessing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotes.Effect of single-strand break on branch migration and folding dynamics of Holliday junctionsIdentification and characterization of the human mus81-eme1 endonuclease.Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cellsGenetic and functional interactions between Mus81-Mms4 and Rad27.Rad22Rad52-dependent repair of ribosomal DNA repeats cleaved by Slx1-Slx4 endonucleaseHuman Mus81 and FANCB independently contribute to repair of DNA damage during replication.Cooperation of RAD51 and RAD54 in regression of a model replication fork.Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein.Survival of the replication checkpoint deficient cells requires MUS81-RAD52 function.A physiological significance of the functional interaction between Mus81 and Rad27 in homologous recombination repairThe Mus81 solution to resolution: generating meiotic crossovers without Holliday junctions.Mms22 preserves genomic integrity during DNA replication in Schizosaccharomyces pombe.The role of DNA-PKcs and artemis in opening viral DNA hairpin termini in various tissues in mice.Cleavage of stalled forks by fission yeast Mus81/Eme1 in absence of DNA replication checkpointAcute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response.Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway.A junction branch point adjacent to a DNA backbone nick directs substrate cleavage by Saccharomyces cerevisiae Mus81-Mms4.Requirement of Rrm3 helicase for repair of spontaneous DNA lesions in cells lacking Srs2 or Sgs1 helicaseBrh2 promotes a template-switching reaction enabling recombinational bypass of lesions during DNA synthesisEsc2 promotes Mus81 complex-activity via its SUMO-like and DNA binding domains.The Intra-S Checkpoint Responses to DNA Damage.Rad54, the motor of homologous recombination.Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion.
P2860
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P2860
Cleavage of model replication forks by fission yeast Mus81-Eme1 and budding yeast Mus81-Mms4.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Cleavage of model replication ...... and budding yeast Mus81-Mms4.
@en
Cleavage of model replication ...... and budding yeast Mus81-Mms4.
@nl
type
label
Cleavage of model replication ...... and budding yeast Mus81-Mms4.
@en
Cleavage of model replication ...... and budding yeast Mus81-Mms4.
@nl
prefLabel
Cleavage of model replication ...... and budding yeast Mus81-Mms4.
@en
Cleavage of model replication ...... and budding yeast Mus81-Mms4.
@nl
P2860
P356
P1476
Cleavage of model replication ...... and budding yeast Mus81-Mms4.
@en
P2093
Fekret Osman
Julie Dixon
P2860
P304
P356
10.1074/JBC.M210006200
P407
P577
2002-12-08T00:00:00Z