Novel role of Janus kinase 1 in the regulation of oncostatin M receptor surface expression.
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Principles of interleukin (IL)-6-type cytokine signalling and its regulationBasal ubiquitin-independent internalization of interferon alpha receptor is prevented by Tyk2-mediated masking of a linear endocytic motifJAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indicationsTYK2 kinase activity is required for functional type I interferon responses in vivoIntracellular signaling prevents effective blockade of oncogenic gp130 mutants by neutralizing antibodies.JAK2 V617F constitutive activation requires JH2 residue F595: a pseudokinase domain target for specific inhibitorsJak3-independent trafficking of the common gamma chain receptor subunit: chaperone function of Jaks revisited.Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs.The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression.The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction.Modulation of growth hormone receptor abundance and function: roles for the ubiquitin-proteasome system.Eliminative signaling by Janus kinases: role in the downregulation of associated receptors.Perspectives for the use of structural information and chemical genetics to develop inhibitors of Janus kinasesActivating Janus kinase pseudokinase domain mutations in myeloproliferative and other blood cancers.Multifarious determinants of cytokine receptor signaling specificity.The common γ-chain cytokine receptor: tricks-and-treats for T cells.RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding.Box 2 region of the oncostatin M receptor determines specificity for recruitment of Janus kinases and STAT5 activation.Interleukin-31 and oncostatin-M mediate distinct signaling reactions and response patterns in lung epithelial cells.The membrane-proximal region of the thrombopoietin receptor confers its high surface expression by JAK2-dependent and -independent mechanisms.Loss of oncostatin M receptor beta in metastatic melanoma cells.Mechanisms of SOCS3 phosphorylation upon interleukin-6 stimulation. Contributions of Src- and receptor-tyrosine kinases.Janus kinases affect thrombopoietin receptor cell surface localization and stability.Jamip1 (marlin-1) defines a family of proteins interacting with janus kinases and microtubules.Janus kinase (Jak) subcellular localization revisited: the exclusive membrane localization of endogenous Janus kinase 1 by cytokine receptor interaction uncovers the Jak.receptor complex to be equivalent to a receptor tyrosine kinase.Fos-Zippered GH Receptor Cytosolic Tails Act as Jak2 Substrates and Signal Transducers.Prerequisites for Functional Interleukin 31 Signaling and Its Feedback Regulation by Suppressor of Cytokine Signaling 3 (SOCS3).Diffusion of Single-Pass Transmembrane Receptors: From the Plasma Membrane into Giant Liposomes.TYK2 activity promotes ligand-induced IFNAR1 proteolysisLong term association of the cytokine receptor gp130 and the Janus kinase Jak1 revealed by FRAP analysis.TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity.The Growth Hormone Receptor: Mechanism of Receptor Activation, Cell Signaling, and Physiological Aspects.
P2860
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P2860
Novel role of Janus kinase 1 in the regulation of oncostatin M receptor surface expression.
description
2002 nî lūn-bûn
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2002年の論文
@ja
2002年学术文章
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2002年学术文章
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2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
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2002年學術文章
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name
Novel role of Janus kinase 1 i ...... M receptor surface expression.
@en
Novel role of Janus kinase 1 i ...... M receptor surface expression.
@nl
type
label
Novel role of Janus kinase 1 i ...... M receptor surface expression.
@en
Novel role of Janus kinase 1 i ...... M receptor surface expression.
@nl
prefLabel
Novel role of Janus kinase 1 i ...... M receptor surface expression.
@en
Novel role of Janus kinase 1 i ...... M receptor surface expression.
@nl
P2093
P2860
P356
P1476
Novel role of Janus kinase 1 i ...... M receptor surface expression.
@en
P2093
Claude Haan
Heike M Hermanns
Hildegard Schmitz-Van De Leur
Hugues Gascan
Iris Behrmann
Peter C Heinrich
Simone Radtke
P2860
P304
11297-11305
P356
10.1074/JBC.M100822200
P407
P577
2002-01-10T00:00:00Z