Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors.
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CDC42 and FGD1 cause distinct signaling and transforming activities.Brain lipid binding protein in axon-Schwann cell interactions and peripheral nerve tumorigenesiscPLA2 regulates the expression of type I interferons and intracellular immunity to Chlamydia trachomatisBasis for signaling specificity difference between Sos and Ras-GRF guanine nucleotide exchange factorsGuanine nucleotide exchange factors: activators of the Ras superfamily of proteinsRole of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5The function of the p190 Rho GTPase-activating protein is controlled by its N-terminal GTP binding domainCloning and characterization of GETS-1, a goldfish Ets family member that functions as a transcriptional repressor in muscle.Epstein-Barr virus immediate-early protein BRLF1 induces the lytic form of viral replication through a mechanism involving phosphatidylinositol-3 kinase activation.Signaling pathways that mediate nerve growth factor-induced increase in expression and release of calcitonin gene-related peptide from sensory neurons.Akt mediates Ras downregulation of RhoB, a suppressor of transformation, invasion, and metastasisAn evolutionarily conserved domain in a subfamily of Rabs is crucial for the interaction with the guanyl nucleotide exchange factor Mss4.Biological and structural characterization of a Ras transforming mutation at the phenylalanine-156 residue, which is conserved in all members of the Ras superfamily.Membrane-targeting potentiates guanine nucleotide exchange factor CDC25 and SOS1 activation of Ras transforming activity.Induction of the early growth response (Egr) family of transcription factors during thymic selection.Epac activation sensitizes rat sensory neurons through activation of Ras.TC21 causes transformation by Raf-independent signaling pathways.Aberrant function of the Ras-related protein TC21/R-Ras2 triggers malignant transformation.Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic RasBinding specificity and mutational analysis of the phosphotyrosine binding domain of the brain-specific adaptor protein ShcC.GRFbeta, a novel regulator of calcium signaling, is expressed in pancreatic beta cells and brain.A dominant-negative strategy for studying roles of G proteins in vivo.The differential effects of the Gly-60 to Ala mutation on the interaction of H-Ras p21 with different downstream targets.The nucleotide binding motif of hepatitis C virus NS4B can mediate cellular transformation and tumor formation without Ha-ras co-transfection.Induction of exocytosis from permeabilized mast cells by the guanosine triphosphatases Rac and Cdc42.Distinct subclasses of small GTPases interact with guanine nucleotide exchange factors in a similar manner.G alpha COOH-terminal minigene vectors dissect heterotrimeric G protein signaling.Guanine nucleotide exchange factors: activators of Ras superfamily proteins.Ras-GRF activates Ha-Ras, but not N-Ras or K-Ras 4B, protein in vivo.Mutant and wild-type Ras: co-conspirators in cancer.Activation of R-Ras by Ras-guanine nucleotide-releasing factor.Aurora kinase A interacts with H-Ras and potentiates Ras-MAPK signaling.Distinct and common pathways in the regulation of insulin-like growth factor-1 receptor gene expression by angiotensin II and basic fibroblast growth factor.Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors.Transformation potential of Ras isoforms correlates with activation of phosphatidylinositol 3-kinase but not ERK.Sensitivity of wild type and mutant ras alleles to Ras specific exchange factors: Identification of factor specific requirements.Structure-based mutagenesis reveals distinct functions for Ras switch 1 and switch 2 in Sos-catalyzed guanine nucleotide exchange.Dual role of Ras and Rho proteins: at the cutting edge of life and death.A novel HRAS substitution (c.266C>G; p.S89C) resulting in decreased downstream signaling suggests a new dimension of RAS pathway dysregulation in human development.Residues of the Rho family GTPases Rho and Cdc42 that specify sensitivity to Dbl-like guanine nucleotide exchange factors.
P2860
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P2860
Identification of residues critical for Ras(17N) growth-inhibitory phenotype and for Ras interaction with guanine nucleotide exchange factors.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Identification of residues cri ...... e nucleotide exchange factors.
@ast
Identification of residues cri ...... e nucleotide exchange factors.
@en
type
label
Identification of residues cri ...... e nucleotide exchange factors.
@ast
Identification of residues cri ...... e nucleotide exchange factors.
@en
prefLabel
Identification of residues cri ...... e nucleotide exchange factors.
@ast
Identification of residues cri ...... e nucleotide exchange factors.
@en
P2093
P2860
P356
P1476
Identification of residues cri ...... e nucleotide exchange factors.
@en
P2093
L A Quilliam
M M Hisaka
S Campbell-Burk
P2860
P304
P356
10.1128/MCB.14.2.1113
P407
P577
1994-02-01T00:00:00Z