Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin - Wikidata - awgldk - TriplyDB

Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin

Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin

http://www.wikidata.org/entity/Q28289403

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Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family Ecto-phosphodiesterase/pyrophosphatase of lymphocytes and non-lymphoid cells: structure and function of the PC-1 family Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production L-histidine inhibits production of lysophosphatidic acid by the tumor-associated cytokine, autotaxin The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate Autotaxin is an exoenzyme possessing 5'-nucleotide phosphodiesterase/ATP pyrophosphatase and ATPase activities Rat liver nucleotide pyrophosphatase/phosphodiesterase is an efficient adenylyl transferase IL-1 beta- and IL-4-induced down-regulation of autotaxin mRNA and PC-1 in fibroblast-like synoviocytes of patients with rheumatoid arthritis (RA)Expression and regulation of Enpp2 in rat uterus during the estrous cycle Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects.LPA receptor signaling: pharmacology, physiology, and pathophysiology.Autotaxin expression and its connection with the TNF-alpha-NF-kappaB axis in human hepatocellular carcinoma.Kinetic analysis of autotaxin reveals substrate-specific catalytic pathways and a mechanism for lysophosphatidic acid distribution Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity Physiological mechanisms of tumor-cell invasion and migration.Autotaxin, a lysophospholipase D with pleomorphic effects in oncogenesis and cancer progression Galectin-3 contributes to melanoma growth and metastasis via regulation of NFAT1 and autotaxin.Phosphodiesterase-Ialpha/autotaxin's MORFO domain regulates oligodendroglial process network formation and focal adhesion organization.Autotaxin (ATX): a multi-functional and multi-modular protein possessing enzymatic lysoPLD activity and matricellular properties Therapeutic potential of autotaxin/lysophospholipase d inhibitors.Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs.Cholera toxin inhibits human hepatocarcinoma cell proliferation in vitro via suppressing ATX/LPA axis.Fowlpox virus encodes nonessential homologs of cellular alpha-SNAP, PC-1, and an orphan human homolog of a secreted nematode protein Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid.Autotaxin promotes motility via G protein-coupled phosphoinositide 3-kinase gamma in human melanoma cells.Retinoic acid-induced expression of autotaxin in N-myc-amplified neuroblastoma cells.Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells.Autotaxin expression in non-small-cell lung cancer.Ecto-nucleotide pyrophosphatase modulates the purinoceptor-mediated signal transduction and is inhibited by purinoceptor antagonists.Autotaxin inhibitors: a perspective on initial medicinal chemistry efforts.Immunohistochemical detection of autotaxin (ATX)/lysophospholipase D (lysoPLD) in submucosal invasive colorectal cancer.Production of extracellular lysophosphatidic acid in the regulation of adipocyte functions and liver fibrosis

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P2860

Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin

http://www.wikidata.org/entity/Q28289403

description

1996 nî lūn-bûn

@nan

1996 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1996 թվականի հոտեմբերին հրատարակված գիտական հոդված

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1996年の論文

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1996年論文

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1996年論文

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1996年論文

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1996年论文

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Stimulation of tumor cell moti ...... se catalytic site of autotaxin

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Stimulation of tumor cell moti ...... se catalytic site of autotaxin

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Stimulation of tumor cell moti ...... se catalytic site of autotaxin

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Stimulation of tumor cell moti ...... se catalytic site of autotaxin

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Stimulation of tumor cell moti ...... se catalytic site of autotaxin

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Stimulation of tumor cell moti ...... se catalytic site of autotaxin

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prefLabel

Stimulation of tumor cell moti ...... se catalytic site of autotaxin

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Stimulation of tumor cell moti ...... se catalytic site of autotaxin

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Stimulation of tumor cell moti ...... se catalytic site of autotaxin

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Journal of Biological Chemistry

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Stimulation of tumor cell moti ...... se catalytic site of autotaxin

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E C Woodhouse

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H Y Lee

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L A Liotta

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M L Stracke

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P T Mulvaney

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T Clair

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P2860

Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus

Cloning, chromosomal localization, and tissue expression of autotaxin from human teratocarcinoma cells

Identification of nucleotide pyrophosphatase/alkaline phosphodiesterase I activity associated with the mouse plasma cell differentiation antigen PC-1

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Molecular cloning of cDNAs for human fibroblast nucleotide pyrophosphatase

Autophosphorylation of PC-1 (alkaline phosphodiesterase I/nucleotide pyrophosphatase) and analysis of the active site

Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension

Tumor cell autocrine motility factor

Interactions of a photo-affinity ATP analog with cation-stimulated adenosine triphosphatases of human red cell membranes

Surface alloantigens of plasma cells

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271

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