MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time
about
The low density lipoprotein receptor-related protein 6 interacts with glycogen synthase kinase 3 and attenuates activityNicotinic ACh receptors as therapeutic targets in CNS disordersLipid microdomain modification sustains neuronal viability in models of Alzheimer's diseaseFRAT-2 preferentially increases glycogen synthase kinase 3 beta-mediated phosphorylation of primed sites, which results in enhanced tau phosphorylationPI-103 and Quercetin Attenuate PI3K-AKT Signaling Pathway in T- Cell Lymphoma Exposed to Hydrogen PeroxideThe peptidylprolyl cis/trans-isomerase Pin1 modulates stress-induced dephosphorylation of Tau in neurons. Implication in a pathological mechanism related to Alzheimer diseaseLoss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease.The Role of Unfolded Protein Response and Mitogen-Activated Protein Kinase Signaling in Neurodegenerative Diseases with Special Focus on Prion DiseasesReversal of fragile X phenotypes by manipulation of AβPP/Aβ levels in Fmr1KO miceNicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.Tau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding.Oligomeric amyloid-{beta} inhibits the proteolytic conversion of brain-derived neurotrophic factor (BDNF), AMPA receptor trafficking, and classical conditioningRegulation of presynaptic Ca2+, synaptic plasticity and contextual fear conditioning by a N-terminal β-amyloid fragment.Insulin resistance in Alzheimer's disease.Combinatorial Tau pseudophosphorylation: markedly different regulatory effects on microtubule assembly and dynamic instability than the sum of the individual partsα7 Nicotinic receptor-mediated astrocytic gliotransmitter release: Aβ effects in a preclinical Alzheimer's mouse model.Glycogen synthase kinase 3β orchestrates microtubule remodeling in compensatory glomerular adaptation to podocyte depletion.Role of key aromatic residues in the ligand-binding domain of alpha7 nicotinic receptors in the agonist action of beta-amyloid.Nicotinic Acetylcholine Receptors Sensitize a MAPK-linked Toxicity Pathway on Prolonged Exposure to β-Amyloid.Activation of GSK-3 and phosphorylation of CRMP2 in transgenic mice expressing APP intracellular domain.Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways.Advances on the understanding of the origins of synaptic pathology in AD.MAPK, beta-amyloid and synaptic dysfunction: the role of RAGE.What's hAPPening at synapses? The role of amyloid β-protein precursor and β-amyloid in neurological disorders.Functional analyses of major cancer-related signaling pathways in Alzheimer's disease etiology.Defining pre-synaptic nicotinic receptors regulated by beta amyloid in mouse cortex and hippocampus with receptor null mutants.Lithium can relieve translational repression of TOP mRNAs elicited by various blocks along the cell cycle in a glycogen synthase kinase-3- and S6-kinase-independent manner.Hepatocyte growth factor suppresses proinflammatory NFkappaB activation through GSK3beta inactivation in renal tubular epithelial cells.Evidence of Abeta- and transgene-dependent defects in ERK-CREB signaling in Alzheimer's models.Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation.Mutant (R406W) human tau is hyperphosphorylated and does not efficiently bind microtubules in a neuronal cortical cell model.NADPH oxidase mediates beta-amyloid peptide-induced activation of ERK in hippocampal organotypic culturesDopamine release in prefrontal cortex in response to beta-amyloid activation of alpha7 * nicotinic receptors.ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures.Research tool: Validation of floxed α7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches.Microtubule binding and clustering of human Tau-4R and Tau-P301L proteins isolated from yeast deficient in orthologues of glycogen synthase kinase-3beta or cdk5.The Cholinergic Antagonist Gymnodimine Improves Aβ and Tau Neuropathology in an in Vitro Model of Alzheimer Disease
P2860
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P2860
MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time
description
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 2004/10/01)
@nl
наукова стаття, опублікована в жовтні 2004
@uk
مقالة علمية (نشرت في أكتوبر 2004)
@ar
name
MAPK recruitment by beta-amylo ...... ysical state and exposure time
@ast
MAPK recruitment by beta-amylo ...... ysical state and exposure time
@en
type
label
MAPK recruitment by beta-amylo ...... ysical state and exposure time
@ast
MAPK recruitment by beta-amylo ...... ysical state and exposure time
@en
prefLabel
MAPK recruitment by beta-amylo ...... ysical state and exposure time
@ast
MAPK recruitment by beta-amylo ...... ysical state and exposure time
@en
P3181
P1476
MAPK recruitment by beta-amylo ...... ysical state and exposure time
@en
P2093
Karen A. Bell
Kelly T. Dineley
P304
P3181
P356
10.1111/J.1471-4159.2004.02722.X
P407
P577
2004-10-01T00:00:00Z