Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1-1.5 Mb and preparation of a PAC-based physical map.
about
The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5qGene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.Fusion of TEL/ETV6 to a novel ACS2 in myelodysplastic syndrome and acute myelogenous leukemia with t(5;12)(q31;p13)An erythroid differentiation signature predicts response to lenalidomide in myelodysplastic syndromeCommon deleted genes in the 5q- syndrome: thrombocytopenia and reduced erythroid colony formation in SPARC null mice.The role of lenalidomide in the management of myelodysplasia with del 5q.Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis.Accommodating haploinsufficient tumor suppressor genes in Knudson's model.Evolutionary conservation of zebrafish linkage group 14 with frequently deleted regions of human chromosome 5 in myeloid malignancies.A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31.A novel insertion ins(18;5)(q21.1;q31.2q35.1) in acute myeloid leukemia associated with microdeletions at 5q31.2, 5q35.1q35.2 and 18q12.3q21.1 detected by oligobased array comparative genomic hybridizationExpression profiling of CD34+ hematopoietic stem/ progenitor cells reveals distinct subtypes of therapy-related acute myeloid leukemia.Genetic deletions in AML and MDS.Genetic pathways leading to therapy-related myeloid neoplasms.Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells.Loss of Tifab, a del(5q) MDS gene, alters hematopoiesis through derepression of Toll-like receptor-TRAF6 signalingRadiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1).Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells.Cytogenetic and genetic pathways in therapy-related acute myeloid leukemia.The genetics of the myelodysplastic syndromes: classical cytogenetics and recent molecular insights.Important genes in the pathogenesis of 5q- syndrome and their connection with ribosomal stress and the innate immune system pathway.Therapy-related myeloid leukemia.Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer.Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice.Biology and treatment of the 5q- syndrome.Molecular dissection of the 5q deletion in myelodysplastic syndrome.Myelodysplastic syndromes with 5q deletion: pathophysiology and role of lenalidomide.p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas.Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis.Chromosome 5q deletion and epigenetic suppression of the gene encoding alpha-catenin (CTNNA1) in myeloid cell transformation.Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates.Progressive chromatin repression and promoter methylation of CTNNA1 associated with advanced myeloid malignancies.Proliferative activity of leukaemic blasts and cytosine arabinoside pharmacodynamics are associated with cytogenetically defined prognostic subgroups in acute myeloid leukaemia.Somatic mutations of the lysyl oxidase gene on chromosome 5q23.1 in colorectal tumors.The 5q- syndrome.Molecular cytogenetic delineation of the critical deleted region in the 5q- syndrome.The unexplored 5q13 locus: a role in hematopoietic malignancies.Chromosome translocations: dangerous liaisons revisited.The 5q- syndrome: biology and treatment.
P2860
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P2860
Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1-1.5 Mb and preparation of a PAC-based physical map.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Molecular delineation of the s ...... n of a PAC-based physical map.
@ast
Molecular delineation of the s ...... n of a PAC-based physical map.
@en
type
label
Molecular delineation of the s ...... n of a PAC-based physical map.
@ast
Molecular delineation of the s ...... n of a PAC-based physical map.
@en
prefLabel
Molecular delineation of the s ...... n of a PAC-based physical map.
@ast
Molecular delineation of the s ...... n of a PAC-based physical map.
@en
P2093
P2860
P356
P1476
Molecular delineation of the s ...... n of a PAC-based physical map.
@en
P2093
J D Eisenbart
M M Le Beau
R A Larson
R Espinosa
P2860
P304
P356
10.1073/PNAS.94.13.6948
P407
P577
1997-06-01T00:00:00Z