A majority of mice show long-term expression of a human beta-globin gene after retrovirus transfer into hematopoietic stem cells.
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Intron requirement for expression of the human purine nucleoside phosphorylase geneCurrent and future alternative therapies for beta-thalassemia majorHematopoietic stem cell gene therapy:assessing the relevance of preclinical modelsThe potential of gene therapy approaches for the treatment of hemoglobinopathies: achievements and challengesTransplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus.High-level beta-globin expression after retroviral transfer of locus activation region-containing human beta-globin gene derivatives into murine erythroleukemia cells.Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.Expression of human alpha-globin and mouse/human hybrid beta-globin genes in murine hemopoietic stem cells transduced by recombinant retroviruses.Gene therapy for the hemoglobin disorders: past, present, and future.Long-term expression of a T-cell receptor beta-chain gene in mice reconstituted with retrovirus-infected hematopoietic stem cells.Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene.The future of gene therapy for stroke.Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cellsTranscriptional Silencing of Retroviral Vectors.Globin gene transfer for the treatment of severe hemoglobinopathies: a paradigm for stem cell-based gene therapy.Retroviral-mediated transfer of the human glucocerebrosidase gene into cultured Gaucher bone marrow.Globin gene transfer as a potential treatment for the beta-thalassaemias and sickle cell disease.Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells.Adeno-associated virus type 2-mediated transduction of murine hematopoietic cells with long-term repopulating ability and sustained expression of a human globin gene in vivo.Hepatic gene therapy: adenovirus enhancement of receptor-mediated gene delivery and expression in primary hepatocytes.Leukemia inhibitory factor improves survival of retroviral vector-infected hematopoietic stem cells in vitro, allowing efficient long-term expression of vector-encoded human adenosine deaminase in vivoProgress toward the genetic treatment of the beta-thalassemias.An internal deletion enhances the transcriptional activity of a recombinant retrovirus in hematopoietic cells in vivo.Expression of the gibbon ape leukemia virus receptor-1 in rhesus macaque tissues.A 36-base-pair core sequence of locus control region enhances retrovirally transferred human beta-globin gene expression.Gene therapy for hemoglobinopathies: progress and challenges.Current status of globin gene therapy for the treatment of beta-thalassaemia.Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vectorLong-term expression of gamma-globin mRNA in mouse erythrocytes from retrovirus vectors containing the human gamma-globin gene fused to the ankyrin-1 promoter.Expression of a swine class II gene in murine bone marrow hematopoietic cells by retroviral-mediated gene transfer.Mutagenesis of retroviral vectors transducing human beta-globin gene and beta-globin locus control region derivatives results in stable transmission of an active transcriptional structureDrug delivery by genetically engineered cell implants.Long-term transplantation of canine keratinocytes made resistant to G418 through retrovirus-mediated gene transfer.Physiological and tissue-specific vectors for treatment of inherited diseases.Gene therapy in thalassemia and hemoglobinopathies.Gene therapy: current status and future directions.Gene transfer into murine hematopoietic stem cells and bone marrow stromal cells.Slow and Steady Wins The Race? Progress in the Development of Vectors for Gene Therapy of β-Thalassemia and Sickle Cell Disease.Comparative analysis of FV vectors with human α- or β-globin gene regulatory elements for the correction of β-thalassemia.The Ongoing Challenge of Hematopoietic Stem Cell-Based Gene Therapy for β-Thalassemia.
P2860
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P2860
A majority of mice show long-term expression of a human beta-globin gene after retrovirus transfer into hematopoietic stem cells.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
A majority of mice show long-t ...... into hematopoietic stem cells.
@ast
A majority of mice show long-t ...... into hematopoietic stem cells.
@en
type
label
A majority of mice show long-t ...... into hematopoietic stem cells.
@ast
A majority of mice show long-t ...... into hematopoietic stem cells.
@en
prefLabel
A majority of mice show long-t ...... into hematopoietic stem cells.
@ast
A majority of mice show long-t ...... into hematopoietic stem cells.
@en
P2093
P2860
P356
P1476
A majority of mice show long-t ...... into hematopoietic stem cells.
@en
P2093
A D Miller
M A Bender
R E Gelinas
P2860
P304
P356
10.1128/MCB.9.4.1426
P407
P577
1989-04-01T00:00:00Z