Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer. - Wikidata - awgldk - TriplyDB

Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer.

Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer.

http://www.wikidata.org/entity/Q42554561

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Crystal Structures of the FAK Kinase in Complex with TAE226 and Related Bis-Anilino Pyrimidine Inhibitors Reveal a Helical DFG Conformation Plasma membrane-associated pY397FAK is a marker of cytotrophoblast invasion in vivo and in vitro Analysis of differentially expressed genes in human hepatocellular carcinoma using suppression subtractive hybridization Ethanol enhances the interaction of breast cancer cells over-expressing ErbB2 with fibronectin RhoC Promotes Metastasis via Activation of the Pyk2 Pathway in Prostate Cancer Inhibition of focal adhesion kinase by PF-562,271 inhibits the growth and metastasis of pancreatic cancer concomitant with altering the tumor microenvironment.Role of FRNK tyrosine phosphorylation in vascular smooth muscle spreading and migration.N-MYC regulates focal adhesion kinase expression in human neuroblastoma.Non-thermal atmospheric pressure plasma inhibits thyroid papillary cancer cell invasion via cytoskeletal modulation, altered MMP-2/-9/uPA activity.The direct effect of focal adhesion kinase (FAK), dominant-negative FAK, FAK-CD and FAK siRNA on gene expression and human MCF-7 breast cancer cell tumorigenesis.Increased expression of focal adhesion kinase in thyroid cancer: immunohistochemical study.Inhibition of focal adhesion kinase and src increases detachment and apoptosis in human neuroblastoma cell lines Growth activation alone is not sufficient to cause metastatic thyroid cancer in a mouse model of follicular thyroid carcinoma Inhibition of focal adhesion kinase decreases tumor growth in human neuroblastoma Effects of thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapies Prognostic biomarkers in ovarian cancer.Combined BRAF(V600E)- and SRC-inhibition induces apoptosis, evokes an immune response and reduces tumor growth in an immunocompetent orthotopic mouse model of anaplastic thyroid cancer.Targeting Pyk2 for therapeutic intervention FAK inhibition with small molecule inhibitor Y15 decreases viability, clonogenicity, and cell attachment in thyroid cancer cell lines and synergizes with targeted therapeutics MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression High focal adhesion kinase expression in breast carcinoma is associated with lymphovascular invasion and triple-negative phenotype.Downregulation of Focal Adhesion Kinase (FAK) by cord blood stem cells inhibits angiogenesis in glioblastoma Characterization of the novel focal adhesion kinase RAFTK in hematopoietic cells.Focal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism.Focal adhesion kinase as a potential target in oncology.Down-regulation of Gli transcription factor leads to the inhibition of migration and invasion of ovarian cancer cells via integrin β4-mediated FAK signaling Biological significance of focal adhesion kinase in ovarian cancer: role in migration and invasion FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells SKI-606, an Src inhibitor, reduces tumor growth, invasion, and distant metastasis in a mouse model of thyroid cancer A novel analysis strategy for integrating methylation and expression data reveals core pathways for thyroid cancer aetiology.Thyroid hormone receptors and cancer.Focal adhesion kinase overexpression and its impact on human osteosarcoma.MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells.Mammary epithelial-specific disruption of focal adhesion kinase retards tumor formation and metastasis in a transgenic mouse model of human breast cancer.Targeting Focal Adhesion Kinase Suppresses the Malignant Phenotype in Rhabdomyosarcoma Cells Moving beyond VEGF for anti-angiogenesis strategies in gynecologic cancer Focal adhesion kinase as an immunotherapeutic target.Focal adhesion kinase versus p53: apoptosis or survival?Proteomic profiling of endothelial invasion revealed receptor for activated C kinase 1 (RACK1) complexed with vimentin to regulate focal adhesion kinase (FAK)Targeting the p53 pathway.

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Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer.

http://www.wikidata.org/entity/Q42554561

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Annals of Surgical Oncology

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G A Dent

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G C Sturge

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L V Owens

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R J Craven

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P2860

Overexpressed Csk tyrosine kinase is localized in focal adhesions, causes reorganization of alpha v beta 5 integrin, and interferes with HeLa cell spreading

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

Structure and expression of c-myc and c-fos proto-oncogenes in thyroid carcinomas.

Thyroid cancer: a lethal endocrine neoplasm.

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100-105

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10.1007/BF02409059

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