C-terminal splice variants of the mouse mu-opioid receptor differ in morphine-induced internalization and receptor resensitization.
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Non-Coding RNAs Regulating Morphine Function: With Emphasis on the In vivo and In vitro Functions of miR-190Morphine induces endocytosis of neuronal mu-opioid receptors through the sustained transfer of Galpha subunits to RGSZ2 proteinsUnidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioidsSelective interactions between helix VIII of the human mu-opioid receptors and the C terminus of periplakin disrupt G protein activationMembrane glycoprotein M6a interacts with the micro-opioid receptor and facilitates receptor endocytosis and recyclingADP-ribosylation factor-dependent phospholipase D2 activation is required for agonist-induced mu-opioid receptor endocytosisPhosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalizationA Role for the Distal Carboxyl Tails in Generating the Novel Pharmacology and G Protein Activation Profile of and Opioid Receptor Hetero-oligomersBiomarkers of morphine tolerance and dependence are prevented by morphine-induced endocytosis of a mutant mu-opioid receptor.Research Resource: Real-Time Analysis of Somatostatin and Dopamine Receptor Signaling in Pituitary Cells Using a Fluorescence-Based Membrane Potential Assay.Essential role of Hrs in a recycling mechanism mediating functional resensitization of cell signaling.Mu-opioid receptor splice variants: sex-dependent regulation by chronic morphine.micro-Opioid receptor endocytosis prevents adaptations in ventral tegmental area GABA transmission induced during naloxone-precipitated morphine withdrawal.Ultrastructural relationship between the mu opioid receptor and its interacting protein, GPR177, in striatal neurons.Morphine-induced receptor endocytosis in a novel knockin mouse reduces tolerance and dependence.An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization.Opioid receptor desensitization: mechanisms and its link to toleranceOpioid pharmaceuticals and addiction: the issues, and research directions seeking solutions.Functional selectivity and time-dependence of μ-opioid receptor desensitization at nerve terminals in the mouse ventral tegmental areaThe N-terminally truncated µ3 and µ3-like opioid receptors are transcribed from a novel promoter upstream of exon 2 in the human OPRM1 gene.Quantitative Detection of µ Opioid Receptor: Western Blot Analyses Using µ Opioid Receptor Knockout MiceFunctional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.Ubiquitination in the first cytoplasmic loop of μ-opioid receptors reveals a hierarchical mechanism of lysosomal down-regulation.Mu-opioid receptor desensitization: is morphine different?Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.Receptor Reserve Moderates Mesolimbic Responses to Opioids in a Humanized Mouse Model of the OPRM1 A118G PolymorphismMu opioid receptor activation of ERK1/2 is GRK3 and arrestin dependent in striatal neuronsProlonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerancePharmacogenetics and anesthesiologists.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Differentiation of opioid drug effects by hierarchical multi-site phosphorylationChronic morphine treatment reduces recovery from opioid desensitization.Identification of five mouse mu-opioid receptor (MOR) gene (Oprm1) splice variants containing a newly identified alternatively spliced exon.Differential expression and HIV-1 regulation of μ-opioid receptor splice variants across human central nervous system cell types.Mu opioids and their receptors: evolution of a concept.Morphine regulates expression of μ-opioid receptor MOR-1A, an intron-retention carboxyl terminal splice variant of the μ-opioid receptor (OPRM1) gene via miR-103/miR-107.Isolating and characterizing three alternatively spliced mu opioid receptor variants: mMOR-1A, mMOR-1O, and mMOR-1P.Heterologous regulation of agonist-independent μ-opioid receptor phosphorylation by protein kinase CRegulation of opioid receptor signalling: implications for the development of analgesic tolerance.Epigenetics of µ-opioid receptors: intersection with HIV-1 infection of the central nervous system.
P2860
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P2860
C-terminal splice variants of the mouse mu-opioid receptor differ in morphine-induced internalization and receptor resensitization.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
C-terminal splice variants of ...... and receptor resensitization.
@en
C-terminal splice variants of ...... and receptor resensitization.
@nl
type
label
C-terminal splice variants of ...... and receptor resensitization.
@en
C-terminal splice variants of ...... and receptor resensitization.
@nl
prefLabel
C-terminal splice variants of ...... and receptor resensitization.
@en
C-terminal splice variants of ...... and receptor resensitization.
@nl
P2093
P2860
P356
P1476
C-terminal splice variants of ...... and receptor resensitization.
@en
P2093
P2860
P304
31408-31414
P356
10.1074/JBC.M100305200
P407
P577
2001-05-18T00:00:00Z