Characterization of two distinct monoclonal antibodies to paired helical filaments: further evidence for fetal-type phosphorylation of the tau in paired helical filaments.
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Molecular Mechanisms in the Pathogenesis of Alzheimer's disease and Tauopathies-Prion-Like Seeded Aggregation and PhosphorylationMemantine Attenuates Alzheimer's Disease-Like Pathology and Cognitive ImpairmentI1PP2A affects tau phosphorylation via association with the catalytic subunit of protein phosphatase 2ABiochemical characterization of the core structure of alpha-synuclein filaments.Up-regulation of inhibitors of protein phosphatase-2A in Alzheimer's disease.Regulation of phosphorylation of tau by cyclin-dependent kinase 5 and glycogen synthase kinase-3 at substrate level.Changes in the ageing brain in health and disease.The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment.Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease.Stable expression in Chinese hamster ovary cells of mutated tau genes causing frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17)Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tauThe physiological phosphorylation of tau is critically changed in fetal brains of individuals with Down syndrome.Dorothy Russell Memorial Lecture. The molecular pathology of Alzheimer's disease: are we any closer to understanding the neurodegenerative process?Somatodendritic localization and hyperphosphorylation of tau protein in transgenic mice expressing the longest human brain tau isoform.Shift from fetal-type to Alzheimer-type phosphorylated Tau proteins in SKNSH-SY 5Y cells treated with okadaic acid.Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau.An experimental rat model of sporadic Alzheimer's disease and rescue of cognitive impairment with a neurotrophic peptide.Molecular analysis of mutant and wild-type tau deposited in the brain affected by the FTDP-17 R406W mutation.3R and 4R tau isoforms in paired helical filaments in Alzheimer's disease.Inhibitors of protein phosphatase-2A from human brain structures, immunocytological localization and activities towards dephosphorylation of the Alzheimer type hyperphosphorylated tau.Epitope mapping of monoclonal antibodies to the paired helical filaments of Alzheimer's disease: identification of phosphorylation sites in tau protein.Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS.Biochemical and ultrastructural study of neurofibrillary tangles in amyotrophic lateral sclerosis/parkinsonism-dementia complex in the Kii peninsula of Japan.Deamidation and isoaspartate formation in smeared tau in paired helical filaments. Unusual properties of the microtubule-binding domain of tau.The regulation of phosphorylation of tau in SY5Y neuroblastoma cells: the role of protein phosphatases.Collapsin response mediator protein-2 is associated with neurofibrillary tangles in Alzheimer's disease.Selective deposition of mutant tau in the FTDP-17 brain affected by the P301L mutation.Characterization of mAb AP422, a novel phosphorylation-dependent monoclonal antibody against tau protein.Abnormally phosphorylated tau in SY5Y human neuroblastoma cells.Rapid Alzheimer-like phosphorylation of tau by the synergistic actions of non-proline-dependent protein kinases and GSK-3.Proline-directed and non-proline-directed phosphorylation of PHF-tau.
P2860
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P2860
Characterization of two distinct monoclonal antibodies to paired helical filaments: further evidence for fetal-type phosphorylation of the tau in paired helical filaments.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
Characterization of two distin ...... u in paired helical filaments.
@en
Characterization of two distin ...... u in paired helical filaments.
@nl
type
label
Characterization of two distin ...... u in paired helical filaments.
@en
Characterization of two distin ...... u in paired helical filaments.
@nl
prefLabel
Characterization of two distin ...... u in paired helical filaments.
@en
Characterization of two distin ...... u in paired helical filaments.
@nl
P2093
P2860
P1476
Characterization of two distin ...... u in paired helical filaments.
@en
P2093
A Watanabe
M Hasegawa
P2860
P304
P356
10.1111/J.1471-4159.1993.TB03491.X
P407
P577
1993-06-01T00:00:00Z