Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB - Wikidata - awgldk - TriplyDB

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

http://www.wikidata.org/entity/Q56567036

about

vCLAP, a caspase-recruitment domain-containing protein of equine Herpesvirus-2, persistently activates the Ikappa B kinases through oligomerization of IKKgamma HTLV-1 Tax-associated hTid-1, a human DnaJ protein, is a repressor of Ikappa B kinase beta subunit Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK Interaction of retroviral Tax oncoproteins with tristetraprolin and regulation of tumor necrosis factor-alpha expression Activation of IKKalpha and IKKbeta through their fusion with HTLV-I tax protein Role of IKKgamma/nemo in assembly of the Ikappa B kinase complex Identification of a novel A20-binding inhibitor of nuclear factor-kappa B activation termed ABIN-2 Nuclear localization of the cell cycle regulator CDH1 and its regulation by phosphorylation Protein profile of tax-associated complexes Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity CREB--a real culprit in oncogenesis Segregation of NF-kappaB activation through NEMO/IKKgamma by Tax and TNFalpha: implications for stimulus-specific interruption of oncogenic signaling Molecular biology and pathogenesis of the human T-cell leukaemia/lymphotropic virus Type-1 (HTLV-1).NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein.HTLV-1 Tax deregulates autophagy by recruiting autophagic molecules into lipid raft microdomains.Persistent activation of NF-kappaB by the tax transforming protein of HTLV-1: hijacking cellular IkappaB kinases.NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ.KSHV vCyclin counters the senescence/G1 arrest response triggered by NF-κB hyperactivation.Stimulation of IKK-gamma oligomerization by the human T-cell leukemia virus oncoprotein Tax.Human T-cell leukemia virus type I and adult T-cell leukemia.Mutual regulation between deubiquitinase CYLD and retroviral oncoprotein Tax Human T-cell leukemia virus type 1 (HTLV-1) and leukemic transformation: viral infectivity, Tax, HBZ and therapy.HTLV-2 Tax immortalizes human CD4+ memory T lymphocytes by oncogenic activation and dysregulation of autophagy.LKB1 tumor suppressor and salt-inducible kinases negatively regulate human T-cell leukemia virus type 1 transcription.NF-kappaB in pathogenesis and treatment of adult T-cell leukemia/lymphoma.Does the HBZ gene represent a new potential target for the treatment of adult T-cell leukemia?Oral administration of an HSP90 inhibitor, 17-DMAG, intervenes tumor-cell infiltration into multiple organs and improves survival period for ATL model mice Modulation of autophagy-like processes by tumor viruses.Regulation of HTLV-1 tax stability, cellular trafficking and NF-κB activation by the ubiquitin-proteasome pathway.Human T cell lymphotropic virus 1 manipulates interferon regulatory signals by controlling the TAK1-IRF3 and IRF4 pathways.In vitro activation of the IkappaB kinase complex by human T-cell leukemia virus type-1 Tax Secretion of the human T cell leukemia virus type I transactivator protein tax.Characterization of a nuclear export signal within the human T cell leukemia virus type I transactivator protein Tax.Human T cell leukemia virus type-I Tax activates human macrophage inflammatory protein-3 alpha/CCL20 gene transcription via the NF-kappa B pathway.Heptad repeats regulate protein phosphatase 2a recruitment to I-kappaB kinase gamma/NF-kappaB essential modulator and are targeted by human T-lymphotropic virus type 1 tax.Latent membrane protein 1 suppresses RASSF1A expression, disrupts microtubule structures and induces chromosomal aberrations in human epithelial cells.Deregulated activation of oncoprotein kinase Tpl2/Cot in HTLV-I-transformed T cells.A novel NF-kappaB pathway involving IKKbeta and p65/RelA Ser-536 phosphorylation results in p53 Inhibition in the absence of NF-kappaB transcriptional activity.Regulation of NF-kappa B2 p100 processing by its cis-acting domain.Tax deregulation of NF-kappaB2 p100 processing involves both beta-TrCP-dependent and -independent mechanisms.

P2860

Q24290608-D8A79541-7519-4A3D-902D-0CF991B31C49 Q24293015-B88A4814-ADC7-46F1-802C-F2920844858E Q24300455-CC0EA45F-9BF2-4ACC-9DFC-18ECE996577A Q28117697-432084F8-7FB3-4761-AB07-52092DCD3748 Q28143127-55D1DE6E-AF6D-4051-99FB-40E42AC9E17D Q28143953-36913D2C-585A-48AD-9775-2472ED4931DF Q28199348-E4EBBD26-1AAD-4319-B3B4-D59BD63AD7A8 Q28206426-98C260D1-2223-462A-BA59-662E3FE53A67 Q28207756-96265C17-3699-4B49-95D2-AE3D622C7D2D Q28213409-C03220BE-9B64-4012-A8D2-0FCD9F678011 Q28306040-1CC41B86-F363-4368-9E5E-86B8DEC23E11 Q28586249-33A044AD-C788-4291-BBCD-8C3EB84B6AF8 Q30698124-4A60C26B-5D0F-40E4-ACCD-19805D7578A5 Q33483337-0720A503-750B-4B0C-B857-83467D279285 Q33794114-CE219DE8-CEA3-4743-A8A5-3C2B0E020417 Q33797174-BE8416B6-0BBB-47C7-AB6D-D99D883CD2C4 Q33892363-38286F6C-66A1-4631-ACA6-5E4FDED32EA6 Q33955300-0CDDD487-3FFE-4162-8572-88DEF12E05B4 Q34159321-2680317D-655A-4770-8533-D8D62E698106 Q35196605-EA169089-9B9E-4FA9-9740-CF0376563991 Q35207092-9790EEEF-893F-4E82-8E4A-32378CCB1971 Q36147455-B04A0225-35CD-4C11-909C-93FF41EF7E8C Q36298491-BF50617F-A2C8-4284-872B-370F8A1E4C9D Q36808614-DE053615-57CC-4FFE-89FB-A7A4843FC9D8 Q37008647-D38EA654-DEE8-46D5-9C78-5E1E13AD14A5 Q37008651-83E725A6-0270-4347-A343-8114957D36E2 Q37148106-B68BC0D4-AD2D-4993-BE2C-05A766B3DEE8 Q37512255-DA9C4689-7B8D-46D7-8888-8AEE07AC46E1 Q38262353-735923D5-6893-4D74-9414-C2160B0CB65D Q38348415-74CC8ACD-3155-470D-B62E-A83A0C19DFB9 Q38631474-61FB4C8E-335E-4644-8DB8-F3376DD95AAA Q38867996-4884CB7A-1E7B-4257-9C82-6A7260A4CC3D Q38867998-DA8C15E2-C1C7-43AF-B69C-FC649A4CFB6A Q39093706-56835B9A-5D19-4804-B87C-30CB2622CAB7 Q40168522-4B6E1CB5-570B-44FD-8BE0-1AFE929AD932 Q40209246-B4795C9F-1547-4066-9404-63012AF40246 Q40299856-228DB747-0036-474F-91C8-4D3BD471B531 Q40478659-A11EA203-2407-49AF-B015-B10971AF690E Q40504235-392C751C-46C7-48D6-BC28-9FD4DBE2BBC3 Q40525571-94EC9E71-6357-4E2C-B978-9A686303D83E

P2860

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

http://www.wikidata.org/entity/Q56567036

description

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

im Juni 1999 veröffentlichter wissenschaftlicher Artikel

@de

scientific article published in Journal of Biological Chemistry

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в червні 1999

@uk

name

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

@en

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

@nl

type

label

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

@en

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

@nl

prefLabel

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

@en

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

@nl

P1433

Q56567036-D284B15F-FC95-426A-9BAA-C70D2504AD35

P1476

Q56567036-6A6D08CD-9AAA-4D6D-8419-AF15F93B8139

P2093

Q56567036-2B8B5F33-4B91-4869-A1EF-CA561401E0D8

Q56567036-DB11FD58-DDF1-4F51-BC03-7D210699BEDB

Q56567036-EF57418D-389B-41DA-AEDA-013C0A71D972

Q56567036-FA301560-EA37-45D6-B576-02BFC883E0A9

P2860

Q56567036-0105D155-5428-4DC7-B536-C78D5D6DD167

Q56567036-0B92D432-9E01-4A72-B464-40D3B78A9639

Q56567036-1B65E336-CDF6-4842-9C79-17D77E82C3F8

Q56567036-2A2EB085-148A-4521-AB54-BDE02E2228AB

Q56567036-39EDB7C6-9EE3-49D6-BB0E-F44E5AB6509D

Q56567036-4527ACA0-961B-4781-98DF-4A8C78400467

Q56567036-45A5BC0A-DF43-449D-A3F5-5F935BAB74FA

Q56567036-479D88A6-4E13-4F79-8FDE-DF5120113F28

Q56567036-513453AB-3A7E-4FBB-BFE8-341333398034

Q56567036-534B1F98-42A4-4D01-9C33-42D25E6CF0B4

P304

Q56567036-43886068-19A9-4366-B874-305186D4CF1E

P31

Q56567036-C8A64CD7-3354-422B-8B1E-083EC443F0FF

P356

Q56567036-C1F8D35D-BA62-4B13-A555-D5E31CD4FEAC

P407

Q56567036-6545D600-36CD-4AEE-A382-EFF2ADEDE105

P433

Q56567036-C71659DD-373E-4CC0-9B9A-79BAFA207E29

P478

Q56567036-4A426B6C-4B80-41FC-9AD0-16A5A5C8D810

P50

Q56567036-A34F5251-1CD9-443C-BCC5-8B9EE28B4A68

P577

Q56567036-16136CAF-C26E-49AB-A0DB-6CD68B774706

P5875

Q56567036-837D8592-9C30-4208-81D8-46491526DEAF

P356

JBC.274.25.17402

P1433

Journal of Biological Chemistry

P1476

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

@en

P2093

Dong-Yan Jin

http://www.w3.org/2001/XMLSchema#string

Karen V. Kibler

http://www.w3.org/2001/XMLSchema#string

Kuan-Teh Jeang

http://www.w3.org/2001/XMLSchema#string

Vincenzo Giordano

http://www.w3.org/2001/XMLSchema#string

P2860

Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation

Functional interaction of the HTLV-1 transactivator Tax with activating transcription factor-4 (ATF4)

IKAP is a scaffold protein of the IkappaB kinase complex

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

Human T cell leukemia virus type 1 oncoprotein Tax targets the human mitotic checkpoint protein MAD1

Molecular determinants of NF-kappaB-inducing kinase action

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

P304

17402-17405

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.274.25.17402

http://www.w3.org/2001/XMLSchema#string

P407

P433

25

http://www.w3.org/2001/XMLSchema#string

P478

274

http://www.w3.org/2001/XMLSchema#string

P50

Hiroyasu Nakano

P577

1999-06-18T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

12935178

http://www.w3.org/2001/XMLSchema#string