POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityAtTRB1–3 Mediates Structural Changes in AtPOT1b to Hold ssDNAHOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitmentThe F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenanceHigher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assemblyProtein requirements for sister telomere association in human cellsTelosome, a mammalian telomere-associated complex formed by multiple telomeric proteinsGenome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cellsTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationConserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotesIn vivo stoichiometry of shelterin componentsOB fold-containing protein 1 (OBFC1), a human homolog of yeast Stn1, associates with TPP1 and is implicated in telomere length regulationTelomere protection by mammalian Pot1 requires interaction with Tpp1POT1 association with TRF2 regulates telomere lengthHuman UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replicationCharacterization of the DNA binding specificity of Shelterin complexesHow the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structuresTelomere dysfunction and cell survival: roles for distinct TIN2-containing complexesHuman protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitroPOT1 and TRF2 cooperate to maintain telomeric integrityFinding the end: recruitment of telomerase to telomeresTIN2-tethered TPP1 recruits human telomerase to telomeres in vivoTelomere protection by TPP1 is mediated by POT1a and POT1bTelomere biology: Rationale for diagnostics and therapeutics in cancerThe short and long telomere syndromes: paired paradigms for molecular medicineMultiple facets of TPP1 in telomere maintenanceHow telomeric protein POT1 avoids RNA to achieve specificity for single-stranded DNAInhibition of yeast telomerase action by the telomeric ssDNA-binding protein, Cdc13pATM and ATR Signaling Regulate the Recruitment of Human Telomerase to TelomeresThe shelterin component TPP1 is a binding partner and substrate for the deubiquitinating enzyme USP7Switching human telomerase on and off with hPOT1 protein in vitroGenetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulationFunctional interaction between telomere protein TPP1 and telomeraseThe TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivityOligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardiansStructure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protectionPOT1b protects telomeres from end-to-end chromosomal fusions and aberrant homologous recombinationPOT1-TPP1 enhances telomerase processivity by slowing primer dissociation and aiding translocation.Multiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA.
P2860
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P2860
POT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complex
description
2004 nî lūn-bûn
@nan
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@ast
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@en
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@en-gb
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@nl
type
label
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@ast
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@en
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@en-gb
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@nl
prefLabel
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@ast
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@en
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@en-gb
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@nl
P2093
P2860
P3181
P356
P1433
P1476
POT1-interacting protein PIP1: ...... POT1 to the TIN2/TRF1 complex
@en
P2093
Andrew N Krutchinsky
Brian T Chait
Diego Loayza
Jeffrey Zheng-Sheng Ye
Sarah M Hooper
P2860
P304
P3181
P356
10.1101/GAD.1215404
P407
P577
2004-07-15T00:00:00Z