Telomere protection by mammalian Pot1 requires interaction with Tpp1
about
Diminished telomeric 3' overhangs are associated with telomere dysfunction in Hoyeraal-Hreidarsson syndromeTelomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongationIn vivo stoichiometry of shelterin componentsPOT1 association with TRF2 regulates telomere lengthCharacterization of the DNA binding specificity of Shelterin complexesFinding the end: recruitment of telomerase to telomeresTIN2-tethered TPP1 recruits human telomerase to telomeres in vivoTelomere dysfunction and chromosome instabilityTelomere protection by TPP1 is mediated by POT1a and POT1bMultiple facets of TPP1 in telomere maintenanceGenetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulationModern genome editing meets telomeres: the many functions of TPP1Functional interaction between telomere protein TPP1 and telomeraseThe TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivityOligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardiansThe Saccharomyces cerevisiae telomerase subunit Est3 binds telomeres in a cell cycle- and Est1-dependent manner and interacts directly with Est1 in vitroMultiple POT1-TPP1 proteins coat and compact long telomeric single-stranded DNA.How telomeres solve the end-protection problem.Telomere protection by TPP1/POT1 requires tethering to TIN2Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.Distinct functions of POT1 at telomeres.No overt nucleosome eviction at deprotected telomeres.Functional dissection of human and mouse POT1 proteins.Multiple roles for MRE11 at uncapped telomeres.Structural insights into POT1-TPP1 interaction and POT1 C-terminal mutations in human cancerPot1 and telomere maintenance.Roles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC in Schizosaccharomyces pombe telomere maintenanceReview paper: origin and molecular pathology of adrenocortical neoplasmsLIM-domain proteins TRIP6 and LPP associate with shelterin to mediate telomere protectionHuman RECQL1 participates in telomere maintenanceInvestigating the role of the Est3 protein in yeast telomere replication.Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Zebrafish as a model system to study the physiological function of telomeric protein TPP1PRL-3 promotes telomere deprotection and chromosomal instability.Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis.The E3 ubiquitin ligase Rnf8 stabilizes Tpp1 to promote telomere end protection.RPA and POT1: friends or foes at telomeres?Mitochondrial localization of telomeric protein TIN2 links telomere regulation to metabolic controlCoordination of transposon expression with DNA replication in the targeting of telomeric retrotransposons in Drosophila.Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1.
P2860
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P248
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P2860
Telomere protection by mammalian Pot1 requires interaction with Tpp1
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@ast
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@en
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@en-gb
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@nl
type
label
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@ast
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@en
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@en-gb
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@nl
prefLabel
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@ast
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@en
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@en-gb
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@nl
P2093
P2860
P921
P3181
P356
P1476
Telomere protection by mammalian Pot1 requires interaction with Tpp1
@en
P2093
Catherine E Keegan
Gary D Hammer
Jan-Peter Daniels
Jeffrey Z-S Ye
Kaori K Takai
Tobias Else
Wilhelm Palm
P2860
P2888
P304
P3181
P356
10.1038/NSMB1270
P407
P577
2007-08-01T00:00:00Z
P5875
P6179
1043541204