NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling
about
Human Zwint-1 specifies localization of Zeste White 10 to kinetochores and is essential for mitotic checkpoint signalingHuman NUF2 interacts with centromere-associated protein E and is essential for a stable spindle microtubule-kinetochore attachmentHec1 sequentially recruits Zwint-1 and ZW10 to kinetochores for faithful chromosome segregation and spindle checkpoint controlMitotic regulation by NIMA-related kinasesLinking kinetochore-microtubule binding to the spindle checkpointStructure and regulation of the human Nek2 centrosomal kinaseDesign of Potent and Selective Hybrid Inhibitors of the Mitotic Kinase Nek2: Structure–Activity Relationship, Structural Biology, and Cellular ActivityCentrosome - a promising anti-cancer targetPALS1 specifies the localization of ezrin to the apical membrane of gastric parietal cells.Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells.Phosphorylation of SKAP by GSK3β ensures chromosome segregation by a temporal inhibition of Kif2b activity.Utilizing evolutionary information and gene expression data for estimating gene networks with bayesian network models.RED, a spindle pole-associated protein, is required for kinetochore localization of MAD1, mitotic progression, and activation of the spindle assembly checkpoint.PPSP: prediction of PK-specific phosphorylation site with Bayesian decision theoryA functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling.Gene expression signature of cigarette smoking and its role in lung adenocarcinoma development and survival.The 68-kDa telomeric repeat binding factor 1 (TRF1)-associated protein (TAP68) interacts with and recruits TRF1 to the spindle pole during mitosisPhospho-regulated ACAP4-Ezrin interaction is essential for histamine-stimulated parietal cell secretion.Nek2 targets the mitotic checkpoint proteins Mad2 and Cdc20: a mechanism for aneuploidy in cancer.Human germline and pan-cancer variomes and their distinct functional profilesTTK kinase is essential for the centrosomal localization of TACC2.CENP-U cooperates with Hec1 to orchestrate kinetochore-microtubule attachment.Adenovirus E1A proteins direct subcellular redistribution of Nek9, a NimA-related kinase.Phospho-regulation of HsCdc14A By Polo-like kinase 1 is essential for mitotic progression.Role of NEK2A in human cancer and its therapeutic potentials.Aurora B kinase activation requires survivin priming phosphorylation by PLK1.Phosphorylation of the Ndc80 complex protein, HEC1, by Nek2 kinase modulates chromosome alignment and signaling of the spindle assembly checkpoint.CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosisGiardia lamblia Nek1 and Nek2 kinases affect mitosis and excystation.Signaling Scaffold Protein IQGAP1 Interacts with Microtubule Plus-end Tracking Protein SKAP and Links Dynamic Microtubule Plus-end to Steer Cell Migration.Kinase Identification with Supervised Laplacian Regularized Least Squares.Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules.Nek2-targeted ASO or siRNA pretreatment enhances anticancer drug sensitivity in triple‑negative breast cancer cells.Septin 7 interacts with centromere-associated protein E and is required for its kinetochore localization.Regulation of a dynamic interaction between two microtubule-binding proteins, EB1 and TIP150, by the mitotic p300/CBP-associated factor (PCAF) orchestrates kinetochore microtubule plasticity and chromosome stability during mitosisCentromere cohesion: regulating the guardian.Targeting NEK2 as a promising therapeutic approach for cancer treatment.The spindle assembly checkpoint in Caenorhabditis elegans: one who lacks Mad1 becomes mad onePinX1 is a novel microtubule-binding protein essential for accurate chromosome segregation.Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression.
P2860
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P2860
NEK2A interacts with MAD1 and possibly functions as a novel integrator of the spindle checkpoint signaling
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@ast
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@en
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@en-gb
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@nl
type
label
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@ast
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@en
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@en-gb
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@nl
prefLabel
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@ast
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@en
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@en-gb
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@nl
P2093
P2860
P921
P356
P1476
NEK2A interacts with MAD1 and ...... e spindle checkpoint signaling
@en
P2093
Arzhang Zereshki
Hongmei Wang
Jianhui Yao
Kashif Ahmed
Xuebiao Yao
Yuzhen Wang
P2860
P304
P356
10.1074/JBC.M314205200
P407
P577
2004-05-07T00:00:00Z