Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120 - Test2 - elhamkhani - TriplyDB

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

http://www.wikidata.org/entity/Q27658449

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Few and far between: how HIV may be evading antibody avidity A Blueprint for HIV Vaccine Discovery HIV-1 neutralizing antibodies: understanding nature's pathways HIV-1 envelope glycoprotein structure Modeling neutralization kinetics of HIV by broadly neutralizing monoclonal antibodies in genital secretions coating the cervicovaginal mucosa HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization Structural plasticity and conformational transitions of HIV envelope glycoprotein gp120 Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility Structure of a clade C HIV-1 gp120 bound to CD4 and CD4-induced antibody reveals anti-CD4 polyreactivity Crystal Structure of the Neutralizing Llama VHH D7 and Its Mode of HIV-1 gp120 Interaction Crystal Structure of PG16 and Chimeric Dissection with Somatically Related PG9: Structure-Function Analysis of Two Quaternary-Specific Antibodies That Effectively Neutralize HIV-1 Structural Basis for Broad and Potent Neutralization of HIV-1 by Antibody VRC01 Crystal Structure of Human Antibody 2909 Reveals Conserved Features of Quaternary Structure-Specific Antibodies That Potently Neutralize HIV-1 Structural Bases of Coronavirus Attachment to Host Aminopeptidase N and Its Inhibition by Neutralizing Antibodies Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing Computation-guided backbone grafting of a discontinuous motif onto a protein scaffold Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody Unliganded HIV-1 gp120 core structures assume the CD4-bound conformation with regulation by quaternary interactions and variable loops Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 Å Cocrystal Structure of gp120 and M48U1 Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120 Structure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry Inhibitors Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites Crystal Structure of a Soluble Cleaved HIV-1 Envelope Trimer Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth 3D visualization of HIV virions by cryoelectron tomography Stabilizing exposure of conserved epitopes by structure guided insertion of disulfide bond in HIV-1 envelope glycoprotein Human antibodies that neutralize HIV-1: identification, structures, and B cell ontogenies A novel small-molecule inhibitor of HIV-1 entry Elicitation of neutralizing antibodies directed against CD4-induced epitope(s) using a CD4 mimetic cross-linked to a HIV-1 envelope glycoprotein Max Bergmann lecture protein epitope mimetics in the age of structural vaccinology Induction of a Tier-1-like Phenotype in Diverse Tier-2 Isolates by Agents that Guide HIV-1 Env to Perturbation-sensitive, Non-native States.Closing the door to human immunodeficiency virus.Stabilized HIV-1 envelope glycoprotein trimers for vaccine use.

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

http://www.wikidata.org/entity/Q27658449

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2009 nî lūn-bûn

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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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SCIENCE.1175868

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

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Ann J Hessell

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Dennis R Burton

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Dimiter S Dimitrov

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James Arthos

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Lei Chen

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Ling Xu

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Lisa Cavacini

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Marie Pancera

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Marshall R Posner

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Mei-Yun Zhang

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P2860

Energetics of the HIV gp120-CD4 binding reaction

Structural definition of a conserved neutralization epitope on HIV-1 gp120

Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates

Molecular architecture of native HIV-1 gp120 trimers

Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120.

The antigenic structure of the HIV gp120 envelope glycoprotein

Antibody neutralization and escape by HIV-1

Efficient neutralization of primary isolates of HIV-1 by a recombinant human monoclonal antibody

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

Identification and characterization of conserved and variable regions in the envelope gene of HTLV-III/LAV, the retrovirus of AIDS.

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1123-7

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10.1126/SCIENCE.1175868

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5956

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326

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Joseph Sodroski

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2009-11-20T00:00:00Z

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40452408

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19965434

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2862588

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