Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
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Dissecting Virus Infectious Cycles by Cryo-Electron MicroscopyHIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchDynamic Viral Glycoprotein Machines: Approaches for Probing Transient States That Drive Membrane FusionStructural and Computational Biology in the Design of Immunogenic Vaccine AntigensConformational Masking and Receptor-Dependent Unmasking of Highly Conserved Env Epitopes Recognized by Non-Neutralizing Antibodies That Mediate Potent ADCC against HIV-1The HIV glycan shield as a target for broadly neutralizing antibodiesStructural insights on the role of antibodies in HIV-1 vaccine and therapyStructures of viral membrane proteins by high-resolution cryoEMAntibody responses to envelope glycoproteins in HIV-1 infectionVaccines for the 21st centuryVirological features associated with the development of broadly neutralizing antibodies to HIV-1HIV broadly neutralizing antibody targetsStructure and Dynamics of the Native HIV-1 Env TrimerComputational Refinement and Validation Protocol for Proteins with Large Variable Regions Applied to Model HIV Env Spike in CD4 and 17b Bound State.Cryo-electron Microscopy Structure of the Native Prototype Foamy Virus Glycoprotein and Virus ArchitectureVaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding SiteAntigenic properties of the human immunodeficiency virus envelope glycoprotein gp120 on virions bound to target cellsStructural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 InfectionStructural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 DonorsCrystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 EnvDevelopmental pathway for potent V1V2-directed HIV-neutralizing antibodiesDeconstructing the Antiviral Neutralizing-Antibody Response: Implications for Vaccine Development and ImmunityCrystal Structure of a Soluble Cleaved HIV-1 Envelope TrimerStructural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12Functional Implications of the Binding Mode of a Human Conformation-Dependent V2 Monoclonal Antibody against HIVDissociation of the trimeric gp41 ectodomain at the lipid–water interface suggests an active role in HIV-1 Env-mediated membrane fusionAntibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope SpikeStructural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domainsProgress in HIV-1 vaccine development.Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and GViral membrane fusion.Targeting host-derived glycans on enveloped viruses for antibody-based vaccine designHIV-1 gp120 as a therapeutic target: navigating a moving labyrinthProtein Crystallography in Vaccine Research and DevelopmentAntibody potency relates to the ability to recognize the closed, pre-fusion form of HIV EnvStructural Constraints Determine the Glycosylation of HIV-1 Envelope TrimersImmunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing EpitopesGeneration and Characterization of a Bivalent HIV-1 Subtype C gp120 Protein Boost for Proof-of-Concept HIV Vaccine Efficacy Trials in Southern AfricaThermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies
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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
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2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
@en
Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
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type
label
Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
@ast
Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
@en
Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
@nl
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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
@ast
Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
@nl
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Cryo-EM Structure of a Fully Glycosylated Soluble Cleaved HIV-1 Envelope Trimer
@en
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Albert Cupo
Andrew B Ward
Clinton S Potter
Dennis R Burton
Dmitry Lyumkis
John P Moore
Natalia de Val
Per-Johan Klasse
Rogier W Sanders
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10.1126/SCIENCE.1245627
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2013-12-20T00:00:00Z