Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
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Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysisUbiquitin modificationsRegulation of Met1-linked polyubiquitin signalling by the deubiquitinase OTULINRBR E3 ubiquitin ligases: new structures, new insights, new questionsParkin structure and functionLinear ubiquitination signals in adaptive immune responsesMolecular Basis and Regulation of OTULIN-LUBAC InteractionMolecular basis for specificity of the Met1-linked polyubiquitin signalLinear ubiquitination in immunityTwo Distinct Types of E3 Ligases Work in Unison to Regulate Substrate UbiquitylationFunctional role of TRIM E3 ligase oligomerization and regulation of catalytic activity.Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1.The ubiquitin-associated domain of cellular inhibitor of apoptosis proteins facilitates ubiquitylationMechanisms of generating polyubiquitin chains of different topology.Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis.Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.Atypical ubiquitin ligase RNF31: the nuclear factor modulator in breast cancer progression.Posttranslational Modification of HOIP Blocks Toll-Like Receptor 4-Mediated Linear-Ubiquitin-Chain FormationUbSRD: The Ubiquitin Structural Relational Database.Structure of a HOIP/E2~ubiquitin complex reveals RBR E3 ligase mechanism and regulation.Linear ubiquitination by LUBEL has a role in Drosophila heat stress response.RBR E3-ligases at workUbiquitin in inflammation: the right linkage makes all the difference.Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways.Met1-linked ubiquitination in immune signalling.Roles of linear ubiquitinylation, a crucial regulator of NF-κB and cell death, in the immune system.The multifaceted role of the E3 ubiquitin ligase HOIL-1: beyond linear ubiquitination.Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity.Structural studies of parkin and sacsin: Mitochondrial dynamics in neurodegenerative diseases.Specificity and disease in the ubiquitin systemParkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity.Post-translational control of NF-κB signaling by ubiquitination.Structural insights into the catalysis and regulation of E3 ubiquitin ligases.Linear ubiquitin chains: enzymes, mechanisms and biologyDiverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signaling.Ubiquitin enzymes in the regulation of immune responses.The AAA+ ATPase p97, a cellular multitool.Determination of the pKa of the N-terminal amino group of ubiquitin by NMR.Mechanism of catalysis, E2 recognition, and autoinhibition for the IpaH family of bacterial E3 ubiquitin ligases.Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms.
P2860
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P2860
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
@ast
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
@en
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
@nl
type
label
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
@ast
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
@en
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
@nl
prefLabel
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
@ast
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
@en
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP
@en
P2093
Aylin C Morris-Davies
Marios G Koliopoulos
Nicholas R Brown
Rohini R Rana
Steven Howell
Veronique Schaeffer
P2860
P2888
P3181
P356
10.1038/NATURE12638
P407
P577
2013-11-21T00:00:00Z
P5875
P6179
1010223778