ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses - Test2 - elhamkhani - TriplyDB

ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses

ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses

http://www.wikidata.org/entity/Q28202998

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BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity Proteolysis of Rad17 by Cdh1/APC regulates checkpoint termination and recovery from genotoxic stress Interaction between human MCM7 and Rad17 proteins is required for replication checkpoint signaling Regulation of TIP60 by ATF2 modulates ATM activation Rad17 recruits the MRE11-RAD50-NBS1 complex to regulate the cellular response to DNA double-strand breaks Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage Purification and characterization of human DNA damage checkpoint Rad complexes Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress Involvement of nucleotide excision and mismatch repair mechanisms in double strand break repair Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin Cdc7-Dbf4 and the human S checkpoint response to UVC The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon Rapid transcriptome responses of maize (Zea mays) to UV-B in irradiated and shielded tissues Insights into APC/C: from cellular function to diseases and therapeutics NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation A role of the C-terminal region of human Rad9 (hRad9) in nuclear transport of the hRad9 checkpoint complex NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage response NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways Human claspin is a ring-shaped DNA-binding protein with high affinity to branched DNA structures LRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distribution DNA damage response genes and the development of cancer metastasis The Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repair Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345 A reduction of licensed origins reveals strain-specific replication dynamics in mice Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway ATR: an essential regulator of genome integrity ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM Viral transport of DNA damage that mimics a stalled replication fork.Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9-1-1 and Rad17-RFC.HIV-1 Vpr-induced apoptosis is cell cycle dependent and requires Bax but not ANT Transient inhibition of ATM kinase is sufficient to enhance cellular sensitivity to ionizing radiation Network architecture of signaling from uncoupled helicase-polymerase to cell cycle checkpoints and trans-lesion DNA synthesis.A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants.Flavored little cigar smoke induces cytotoxicity and apoptosis in airway epithelia.

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ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses

http://www.wikidata.org/entity/Q28202998

description

2001 nî lūn-bûn

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2001 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2001 թվականի հունիսին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年论文

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name

ATR/ATM-mediated phosphorylati ...... for genotoxic stress responses

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ATR/ATM-mediated phosphorylati ...... for genotoxic stress responses

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ATR/ATM-mediated phosphorylati ...... for genotoxic stress responses

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ATR/ATM-mediated phosphorylati ...... for genotoxic stress responses

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ATR/ATM-mediated phosphorylati ...... for genotoxic stress responses

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ATR/ATM-mediated phosphorylati ...... for genotoxic stress responses

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ATR/ATM-mediated phosphorylati ...... for genotoxic stress responses

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ATR/ATM-mediated phosphorylati ...... for genotoxic stress responses

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ATR/ATM-mediated phosphorylati ...... for genotoxic stress responses

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A Ali

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D A Richardson

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K M Brumbaugh

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R S Tibbetts

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R T Abraham

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S M Chen

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X F Wang

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Y Fang

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P2860

A role for ATR in the DNA damage-induced phosphorylation of p53

The human checkpoint protein hRad17 interacts with the PCNA-like proteins hRad1, hHus1, and hRad9

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

A simplified system for generating recombinant adenoviruses

The DNA damage response: putting checkpoints in perspective

Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage

The G2-phase DNA-damage checkpoint

Substrate specificities and identification of putative substrates of ATM kinase family members

ATM and ATR: networking cellular responses to DNA damage

Enhanced phosphorylation of p53 by ATM in response to DNA damage

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100947

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10.1038/35082110

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6840

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411

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2001-06-21T00:00:00Z

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11418864

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phosphorylation