Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage - Test2 - elhamkhani - TriplyDB

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

http://www.wikidata.org/entity/Q24672492

about

Dissociation of cohesin from chromosome arms and loss of arm cohesion during early mitosis depends on phosphorylation of SA2.Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint MDC1 is a mediator of the mammalian DNA damage checkpoint The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation ATM-dependent phosphorylation of ATF2 is required for the DNA damage response Coordination of DNA damage responses via the Smc5/Smc6 complex The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells RPGR-ORF15, which is mutated in retinitis pigmentosa, associates with SMC1, SMC3, and microtubule transport proteins Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint The combined status of ATM and p53 link tumor development with therapeutic response Cdc7-Dbf4 and the human S checkpoint response to UVC BRCA Mutations, DNA Repair Deficiency, and Ovarian Aging Mechanisms of cohesin-mediated gene regulation and lessons learned from cohesinopathies The ancient and evolving roles of cohesin in gene expression and DNA repair A new thermosensitive smc-3 allele reveals involvement of cohesin in homologous recombination in C. elegans Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development Structure of a Second BRCT Domain Identified in the Nijmegen Breakage Syndrome Protein Nbs1 and its Function in an MDC1-Dependent Localization of Nbs1 to DNA Damage Sites Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks.Ataxia-telangiectasia-mutated dependent phosphorylation of Artemis in response to DNA damage.SMC1 coordinates DNA double-strand break repair pathways.Esc4p, a new target of Mec1p (ATR), promotes resumption of DNA synthesis after DNA damage.Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylation DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation MDC1 is required for the intra-S-phase DNA damage checkpoint Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks Nuclear ataxia-telangiectasia mutated (ATM) mediates the cellular response to DNA double strand breaks in human neuron-like cells A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation Cell-cycle checkpoints and cancer Cohesin: functions beyond sister chromatid cohesion Cohesin Is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes Involvement of Hus1 in the chain elongation step of DNA replication after exposure to camptothecin or ionizing radiation Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy Separase loss of function cooperates with the loss of p53 in the initiation and progression of T- and B-cell lymphoma, leukemia and aneuploidy in mice A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM

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Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

http://www.wikidata.org/entity/Q24672492

description

2002 nî lūn-bûn

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2002 թուականի Մարտին հրատարակուած գիտական յօդուած

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2002 թվականի մարտին հրատարակված գիտական հոդված

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2002年の論文

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2002年論文

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2002年論文

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2002年論文

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2002年論文

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Involvement of the cohesin pro ...... endent responses to DNA damage

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Involvement of the cohesin pro ...... endent responses to DNA damage

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Involvement of the cohesin pro ...... endent responses to DNA damage

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Involvement of the cohesin pro ...... endent responses to DNA damage

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Involvement of the cohesin pro ...... endent responses to DNA damage

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Involvement of the cohesin pro ...... endent responses to DNA damage

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Involvement of the cohesin pro ...... endent responses to DNA damage

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Involvement of the cohesin pro ...... endent responses to DNA damage

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Involvement of the cohesin pro ...... endent responses to DNA damage

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Genes & Development

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Involvement of the cohesin pro ...... endent responses to DNA damage

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Bo Xu

http://www.w3.org/2001/XMLSchema#string

Michael B Kastan

http://www.w3.org/2001/XMLSchema#string

Seong-Tae Kim

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

A role for ATR in the DNA damage-induced phosphorylation of p53

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

Chk2 activation dependence on Nbs1 after DNA damage

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

Yeast cohesin complex requires a conserved protein, Eco1p(Ctf7), to establish cohesion between sister chromatids during DNA replication

SMC-mediated chromosome mechanics: a conserved scheme from bacteria to vertebrates?

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560-70

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3701572

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10.1101/GAD.970602

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5

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16

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11486102

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11877376

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155347

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