E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer - Test2 - elhamkhani - TriplyDB

E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer

E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer

http://www.wikidata.org/entity/Q28270616

about

The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex E2-RING expansion of the NEDD8 cascade confers specificity to cullin modification SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways RosettaDesign server for protein design E2 enzymes: more than just middle men RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination RINGs of good and evil: RING finger ubiquitin ligases at the crossroads of tumour suppression and oncogenesis Basis for a ubiquitin-like protein thioester switch toggling E1–E2 affinity Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78 Structure-based Protocol for Identifying Mutations that Enhance Protein–Protein Binding Affinities Crystal structure of SopA, a Salmonella effector protein mimicking a eukaryotic ubiquitin ligase Mechanistic insights into active site-associated polyubiquitination by the ubiquitin-conjugating enzyme Ube2g2 E2 interaction and dimerization in the crystal structure of TRAF6 A Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination Activities Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex A Dual E3 Mechanism for Rub1 Ligation to Cdc53 Structure and function of a HECT domain ubiquitin-binding site A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms Selective Recruitment of an E2 Ubiquitin Complex by an E3 Ubiquitin Ligase Synthesis of free and proliferating cell nuclear antigen-bound polyubiquitin chains by the RING E3 ubiquitin ligase Rad5.Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 Autoregulation of the 26S proteasome by in situ ubiquitination E2s: structurally economical and functionally replete Dimeric Ube2g2 simultaneously engages donor and acceptor ubiquitins to form Lys48-linked ubiquitin chains Building ubiquitin chains: E2 enzymes at work The N terminus of Cbl-c regulates ubiquitin ligase activity by modulating affinity for the ubiquitin-conjugating enzyme.Engineering a ubiquitin ligase reveals conformational flexibility required for ubiquitin transfer HPV E6, E6AP and cervical cancer.Engineering a protein-protein interface using a computationally designed library Exploring the RING-catalyzed ubiquitin transfer mechanism by MD and QM/MM calculations.Orthogonal ubiquitin transfer through engineered E1-E2 cascades for protein ubiquitination Computational design of a PAK1 binding protein.Computational design of second-site suppressor mutations at protein-protein interfaces Protein neddylation: beyond cullin-RING ligases.Redesign of the PAK1 autoinhibitory domain for enhanced stability and affinity in biosensor applications.Twists and turns in ubiquitin-like protein conjugation cascades.The ubiquitination machinery of the ubiquitin system.

P2860

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P2860

E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer

http://www.wikidata.org/entity/Q28270616

description

2005 nî lūn-bûn

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2005 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

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2005年論文

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2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

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2005年論文

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2005年论文

@wuu

name

E2 conjugating enzymes must di ...... in and ubiquitin-like transfer

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E2 conjugating enzymes must di ...... in and ubiquitin-like transfer

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E2 conjugating enzymes must di ...... in and ubiquitin-like transfer

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type

label

E2 conjugating enzymes must di ...... in and ubiquitin-like transfer

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E2 conjugating enzymes must di ...... in and ubiquitin-like transfer

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E2 conjugating enzymes must di ...... in and ubiquitin-like transfer

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prefLabel

E2 conjugating enzymes must di ...... in and ubiquitin-like transfer

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E2 conjugating enzymes must di ...... in and ubiquitin-like transfer

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E2 conjugating enzymes must di ...... in and ubiquitin-like transfer

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P1433

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P1476

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P2860

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P3181

P356

P1433

Nature Structural & Molecular Biology

P1476

E2 conjugating enzymes must di ...... in and ubiquitin-like transfer

@en

P2093

Brenda A Schulman

http://www.w3.org/2001/XMLSchema#string

Brian Kuhlman

http://www.w3.org/2001/XMLSchema#string

Danny T Huang

http://www.w3.org/2001/XMLSchema#string

David M Duda

http://www.w3.org/2001/XMLSchema#string

Ziad M Eletr

http://www.w3.org/2001/XMLSchema#string

P2860

Design of a Novel Globular Protein Fold with Atomic-Level Accuracy

Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1

Structure of an E6AP-UbcH7 complex: insights into ubiquitination by the E2-E3 enzyme cascade

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail

The Doc1 subunit is a processivity factor for the anaphase-promoting complex.

Ubiquitin: structures, functions, mechanisms

NEDD8 recruits E2-ubiquitin to SCF E3 ligase.

Protein interactions within the N-end rule ubiquitin ligation pathway.

Release of ubiquitin-charged Cdc34-S - Ub from the RING domain is essential for ubiquitination of the SCF(Cdc4)-bound substrate Sic1.

P2888

P304

933-4

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P31

scholarly article

P3181

3215086

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P356

10.1038/NSMB984

http://www.w3.org/2001/XMLSchema#string

P407

P433

10

http://www.w3.org/2001/XMLSchema#string

P478

12

http://www.w3.org/2001/XMLSchema#string

P577

2005-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7619569

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P6179

1042490936

http://www.w3.org/2001/XMLSchema#string

P698

16142244

http://www.w3.org/2001/XMLSchema#string