Fanconi anaemia and the repair of Watson and Crick DNA crosslinks - Test2 - elhamkhani - TriplyDB

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

http://www.wikidata.org/entity/Q28283549

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FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctions Functions of Ubiquitin and SUMO in DNA Replication and Replication Stress Interplay between Fanconi anemia and homologous recombination pathways in genome integrity Functions and regulation of the multitasking FANCM family of DNA motor proteins Photosensitive human syndromes Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer Therapy Mechanism and regulation of incisions during DNA interstrand cross-link repair DNA double-strand break repair pathway choice and cancer The inherited bone marrow failure syndromes Fanconi anemia and the cell cycle: new perspectives on aneuploidy Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes The role of ADP-ribosylation in regulating DNA interstrand crosslink repair Slx4 and Rtt107 control checkpoint signalling and DNA resection at double-strand breaks.DNA polymerase θ (POLQ), double-strand break repair, and cancer Modeling Human Bone Marrow Failure Syndromes Using Pluripotent Stem Cells and Genome Engineering Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer A Dominant Mutation in Human RAD51 Reveals Its Function in DNA Interstrand Crosslink Repair Independent of Homologous Recombination Biophysical characterization of the interaction between FAAP20-UBZ4 domain and Rev1-BRCT domain A novel Fanconi anaemia subtype associated with a dominant-negative mutation in RAD51 XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4 PALB2: the hub of a network of tumor suppressors involved in DNA damage responses Mechanism of suppression of chromosomal instability by DNA polymerase POLQ Exome-wide somatic microsatellite variation is altered in cells with DNA repair deficiencies Functional Significance of Nuclear α Spectrin.AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia.Multiple interactions of the intrinsically disordered region between the helicase and nuclease domains of the archaeal Hef protein Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data Central nervous system abnormalities in Fanconi anaemia: patterns and frequency on magnetic resonance imaging.ERCC6L2 mutations link a distinct bone-marrow-failure syndrome to DNA repair and mitochondrial function.Genetic predisposition syndromes: when should they be considered in the work-up of MDS?The histone-fold complex MHF is remodeled by FANCM to recognize branched DNA and protect genome stability.A concomitant loss of dormant origins and FANCC exacerbates genome instability by impairing DNA replication fork progression.Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA.A novel splice site mutation in the noncoding region of BRCA2: implications for Fanconi anemia and familial breast cancer diagnostics.Insight into the roles of helicase motif Ia by characterizing Fanconi anemia group J protein (FANCJ) patient mutations Molecular analysis of Fanconi anemia: the experience of the Bone Marrow Failure Study Group of the Italian Association of Pediatric Onco-Hematology.Fanca deficiency reduces A/T transitions in somatic hypermutation and alters class switch recombination junctions in mouse B cells.The genetic and biochemical basis of FANCD2 monoubiquitination

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Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

http://www.wikidata.org/entity/Q28283549

description

2013 nî lūn-bûn

@nan

2013 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հունվարին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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type

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Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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prefLabel

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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P1476

Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

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Molly C Kottemann

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The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

UBE2T is the E2 in the Fanconi anemia pathway and undergoes negative autoregulation

Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI

The FANCJ/MutLalpha interaction is required for correction of the cross-link response in FA-J cells

Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair

Drosophila MUS312 and the vertebrate ortholog BTBD12 interact with DNA structure-specific endonucleases in DNA repair and recombination

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleases

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

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356-63

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scholarly article

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1012778

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10.1038/NATURE11863

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7432

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493

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Agata Smogorzewska

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2013-01-17T00:00:00Z

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1019090063

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23325218

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3700363

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