CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
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Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleusCircadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligaseGlobal-genome Nucleotide Excision Repair Controlled by Ubiquitin/Sumo ModifiersXeroderma pigmentosum group C sensor: unprecedented recognition strategy and tight spatiotemporal regulationThe Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and RepairThe role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implicationsInhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapyModification by ubiquitin-like proteins: significance in apoptosis and autophagy pathwaysGenetically engineered mouse models for functional studies of SKP1-CUL1-F-box-protein (SCF) E3 ubiquitin ligasesXPC: Going where no DNA damage sensor has gone beforeDistinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4BUbiquitylation, neddylation and the DNA damage responseCullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complexEssential role of the CUL4B ubiquitin ligase in extra-embryonic tissue development during mouse embryogenesisA novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phaseGenetic abolishment of hepatocyte proliferation activates hepatic stem cellsX-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expressionUbiquitin E3 ligase CRL4(CDT2/DCAF2) as a potential chemotherapeutic target for ovarian surface epithelial cancerCRL4Cdt2: master coordinator of cell cycle progression and genome stabilityCul4B regulates neural progenitor cell growth.CC3/TIP30 affects DNA damage repair.Chromatin retention of DNA damage sensors DDB2 and XPC through loss of p97 segregase causes genotoxicity.A novel lncRNA uc.134 represses hepatocellular carcinoma progression by inhibiting CUL4A-mediated ubiquitination of LATS1.Integrated analysis of genome-wide copy number alterations and gene expression in microsatellite stable, CpG island methylator phenotype-negative colon cancer.Integrative analysis of multi-omics data reveals distinct impacts of DDB1-CUL4 associated factors in human lung adenocarcinomas.CRL4BDCAF11 E3 ligase targets p21 for degradation to control cell cycle progression in human osteosarcoma cellsCUL4A contributes to the biology of basal-like breast tumors through modulation of cell growth and antitumor immune response.Targetome profiling and functional genetics implicate miR-618 in lymphomagenesisThe role of cullin4B in human cancers.Lung tumourigenesis in a conditional Cul4A transgenic mouse model.Crossover localisation is regulated by the neddylation posttranslational regulatory pathway.Regulation of nucleotide excision repair by UV-DDB: prioritization of damage recognition to internucleosomal DNACul4A is essential for spermatogenesis and male fertility.Transgenic mice for cre-inducible overexpression of the Cul4A gene.The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis.Ubiquitin-specific protease 7 regulates nucleotide excision repair through deubiquitinating XPC protein and preventing XPC protein from undergoing ultraviolet light-induced and VCP/p97 protein-regulated proteolysis.Cell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase.Lack of Cul4b, an E3 ubiquitin ligase component, leads to embryonic lethality and abnormal placental development.Improved ex vivo expansion of adult hematopoietic stem cells by overcoming CUL4-mediated degradation of HOXB4.Cullins and cancer.
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P2860
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
description
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
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im Mai 2009 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2009/05/14)
@sk
vědecký článek publikovaný v roce 2009
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wetenschappelijk artikel (gepubliceerd op 2009/05/14)
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наукова стаття, опублікована в травні 2009
@uk
مقالة علمية (نشرت في 14-5-2009)
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name
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
@ast
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
@en
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
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type
label
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
@ast
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
@en
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
@nl
prefLabel
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
@ast
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
@en
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
@nl
P2093
P2860
P3181
P1433
P1476
CUL4A abrogation augments DNA damage response and protection against skin carcinogenesis
@en
P2093
Jeffrey Hannah
Jianxuan Zhang
Pengbo Zhou
Sara B Peters
Sharrell Lee
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2009.04.020
P577
2009-05-01T00:00:00Z