A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development.
about
Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1A critical role for the transcription factor Scl in platelet production during stress thrombopoiesisEssential and instructive roles of GATA factors in eosinophil developmentThe TR2 and TR4 orphan nuclear receptors repress Gata1 transcriptionX-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interactionCCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 functionErythroid Krüppel-like factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the beta-globin locus control regionGATA-1 mediates auto-regulation of Gfi-1B transcription in K562 cellsMegakaryocyte biology and related disordersSpi-1/PU.1 is a positive regulator of the Fli-1 gene involved in inhibition of erythroid differentiation in friend erythroleukemic cell linesGATA-1 and NF-Y cooperate to mediate erythroid-specific transcription of Gfi-1B geneExtracellular signal-regulated kinase induces the megakaryocyte GPIIb/CD41 gene through MafB/KreislerThe aryl hydrocarbon receptor (AHR) transcription factor regulates megakaryocytic polyploidizationOsteoimmunology: interactions of the bone and immune systemCyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidizationAn EF hand mutation in Stim1 causes premature platelet activation and bleeding in miceThe contribution of mouse models to the understanding of constitutional thrombocytopeniaMaster regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignanciesStem cell autotomy and niche interaction in different systemsTranscription factors in late megakaryopoiesis and related platelet disordersThe evolving role of the aryl hydrocarbon receptor (AHR) in the normophysiology of hematopoiesisPluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical applicationMyeloid leukemia in Down syndromeThe emerging role of GATA transcription factors in development and diseaseThe secret life of a megakaryocyte: emerging roles in bone marrow homeostasis controlAbsence of mutations in the HoxA10, HoxA11 and HoxD11 nucleotide coding sequences in thrombocytopenia with absent radius syndromePLZF induces megakaryocytic development, activates Tpo receptor expression and interacts with GATA1 proteinCloning and analysis of the thrombopoietin-induced megakaryocyte-specific glycoprotein VI promoter and its regulation by GATA-1, Fli-1, and Sp1Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factorsBromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genesTranscription factor GATA-1 and Down syndrome leukemogenesisDiscovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancyAnalysis of disease-causing GATA1 mutations in murine gene complementation systemsInduction of megakaryocytic differentiation in primary human erythroblasts: a physiological basis for leukemic lineage plasticity.GATA-1 associates with and inhibits p53.Zinc finger protein, Hzf, is required for megakaryocyte development and hemostasisFailure of megakaryopoiesis and arrested erythropoiesis in mice lacking the GATA-1 transcriptional cofactor FOGTranslational isoforms of FOG1 regulate GATA1-interacting complexesMutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopeniaThe critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12
P2860
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P2860
A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development.
description
1997 nî lūn-bûn
@nan
1997 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
A lineage-selective knockout e ...... rowth and platelet development
@nl
A lineage-selective knockout e ...... owth and platelet development.
@ast
A lineage-selective knockout e ...... owth and platelet development.
@en
type
label
A lineage-selective knockout e ...... rowth and platelet development
@nl
A lineage-selective knockout e ...... owth and platelet development.
@ast
A lineage-selective knockout e ...... owth and platelet development.
@en
prefLabel
A lineage-selective knockout e ...... rowth and platelet development
@nl
A lineage-selective knockout e ...... owth and platelet development.
@ast
A lineage-selective knockout e ...... owth and platelet development.
@en
P2093
P2860
P3181
P356
P1433
P1476
A lineage-selective knockout e ...... owth and platelet development.
@en
P2093
Fujiwara Y
McDevitt MA
Shivdasani RA
P2860
P304
P3181
P356
10.1093/EMBOJ/16.13.3965
P407
P577
1997-07-01T00:00:00Z