Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway
about
A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons.The N-end rule pathwayDiscovery of cellular regulation by protein degradationFemale lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathwaySynthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathwayStructural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligasesRPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuit.Demographically-Based Evaluation of Genomic Regions under Selection in Domestic DogsConstruction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathwayGlutamine-specific N-terminal amidase, a component of the N-end rule pathwayBiochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systemsAn improved workflow for quantitative N-terminal charge-based fractional diagonal chromatography (ChaFRADIC) to study proteolytic events in Arabidopsis thaliana.The substrate recognition domains of the N-end rule pathway.Molecular characterization of mouse gastric epithelial progenitor cells.Felix Hoppe-Seyler Lecture 2000. The ubiquitin system and the N-end rule pathway.RGS4 and RGS5 are in vivo substrates of the N-end rule pathwayThe N-end rule pathway and regulation by proteolysisPairs of dipeptides synergistically activate the binding of substrate by ubiquitin ligase through dissociation of its autoinhibitory domain.Crystal structure of human protein N-terminal glutamine amidohydrolase, an initial component of the N-end rule pathway.Aminoacyl-transferases and the N-end rule pathway of prokaryotic/eukaryotic specificity in a human pathogenImpact of the N-terminal amino acid on targeted protein degradation.Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway.Male-biased autosomal effect of 16p13.11 copy number variation in neurodevelopmental disorders.Phenotypic manifestations of copy number variation in chromosome 16p13.11.Expression and biochemical characterization of the human enzyme N-terminal asparagine amidohydrolase.Varying intertrial interval reveals temporally defined memory deficits and enhancements in NTAN1-deficient mice.Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type miceCopy number variations of chromosome 16p13.1 region associated with schizophrenia.Augmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis.UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagyRecurrent reciprocal deletions and duplications of 16p13.11: the deletion is a risk factor for MR/MCA while the duplication may be a rare benign variant.Multivalency-assisted control of intracellular signaling pathways: application for ubiquitin- dependent N-end rule pathway.Genotype to phenotype-discovery and characterization of novel genomic disorders in a "genotype-first" era.Protein Quality Control by Molecular Chaperones in Neurodegeneration.New discoveries in schizophrenia genetics reveal neurobiological pathways: A review of recent findings.Clinical utility gene card for: 16p13.11 microdeletion syndromePhysiological functions and clinical implications of the N-end rule pathway.NDE1 and NDEL1 from genes to (mal)functions: parallel but distinct roles impacting on neurodevelopmental disorders and psychiatric illness.Substrate-binding sites of UBR1, the ubiquitin ligase of the N-end rule pathway.Behavioral characterization of mice lacking the ubiquitin ligase UBR1 of the N-end rule pathway.
P2860
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P2860
Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway
description
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Juni 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/06/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/06/01)
@nl
наукова стаття, опублікована в червні 2000
@uk
مقالة علمية (نشرت في يونيو 2000)
@ar
name
Altered activity, social behav ...... anch of the N-end rule pathway
@ast
Altered activity, social behav ...... anch of the N-end rule pathway
@en
Altered activity, social behav ...... anch of the N-end rule pathway
@nl
type
label
Altered activity, social behav ...... anch of the N-end rule pathway
@ast
Altered activity, social behav ...... anch of the N-end rule pathway
@en
Altered activity, social behav ...... anch of the N-end rule pathway
@nl
prefLabel
Altered activity, social behav ...... anch of the N-end rule pathway
@ast
Altered activity, social behav ...... anch of the N-end rule pathway
@en
Altered activity, social behav ...... anch of the N-end rule pathway
@nl
P2093
P2860
P1476
Altered activity, social behav ...... anch of the N-end rule pathway
@en
P2093
A. S. Kashina
A. Varshavsky
I. V. Davydov
J. K. Yoon
S. A. Balogh
V. H. Denenberg
Y. T. Kwon
P2860
P304
P356
10.1128/MCB.20.11.4135-4148.2000
P407
P577
2000-06-01T00:00:00Z