Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening.

Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening.

Item
http://www.wikidata.org/entity/Q33267859
Comparative structural, kinetic and inhibitor studies of Trypanosoma brucei trypanothione reductase with T. cruziDihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of their Binding Mode by Protein CrystallographyAdvancing drug innovation for neglected diseases-criteria for lead progressionInvestigation of trypanothione reductase as a drug target in Trypanosoma brucei.Lessons learnt from assembling screening libraries for drug discovery for neglected diseases.Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis.Inhibitors of Leishmania GDP-mannose pyrophosphorylase identified by high-throughput screening of small-molecule chemical librarySynthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductase.Trypanocidal drugs: mechanisms, resistance and new targets.Drug discovery and human African trypanosomiasis: a disease less neglected?Synthetic Medicinal Chemistry in Chagas' Disease: Compounds at The Final Stage of "Hit-To-Lead" Phase.Trypanothione reductase high-throughput screening campaign identifies novel classes of inhibitors with antiparasitic activity.
P2860

Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening.

Item
http://www.wikidata.org/entity/Q33267859
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Discovery of 2-iminobenzimidaz ...... by high-throughput screening.
@ast
Discovery of 2-iminobenzimidaz ...... by high-throughput screening.
@en
type
label
Discovery of 2-iminobenzimidaz ...... by high-throughput screening.
@ast
Discovery of 2-iminobenzimidaz ...... by high-throughput screening.
@en
prefLabel
Discovery of 2-iminobenzimidaz ...... by high-throughput screening.
@ast
Discovery of 2-iminobenzimidaz ...... by high-throughput screening.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P921
P932
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P1433
P1476
Discovery of 2-iminobenzimidaz ...... by high-throughput screening.
@en
P2093
P2860
P304
P31
P356
10.1016/J.BMCL.2006.11.090
P407
P433
P478
P50
P577
P5875
P698
P921
P932