The HRDC domain of BLM is required for the dissolution of double Holliday junctions - Test2 - elhamkhani - TriplyDB

The HRDC domain of BLM is required for the dissolution of double Holliday junctions

The HRDC domain of BLM is required for the dissolution of double Holliday junctions

http://www.wikidata.org/entity/Q33899656

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Different quaternary structures of human RECQ1 are associated with its dual enzymatic activity BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates The RecQ DNA helicases in DNA repair Human premature aging, DNA repair and RecQ helicases The Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNA Replication of Structured DNA and its implication in epigenetic stability Crystal structure of the HRDC domain of human Werner syndrome protein, WRN Structure and function of the regulatory C-terminal HRDC domain from Deinococcus radiodurans RecQ Structure and function of the regulatory HRDC domain from human Bloom syndrome protein Structure of the RecQ C-terminal domain of human Bloom syndrome protein Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA An essential DNA strand-exchange activity is conserved in the divergent N-termini of BLM orthologs.Evidence that a RecQ helicase slows senescence by resolving recombining telomeres The broken genome: genetic and pharmacologic approaches to breaking DNA RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes Human RECQ1 is a DNA damage responsive protein required for genotoxic stress resistance and suppression of sister chromatid exchanges.The RTR Complex Partner RMI2 and the DNA Helicase RTEL1 Are Both Independently Involved in Preserving the Stability of 45S rDNA Repeats in Arabidopsis thaliana.WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3 Distinct roles of RECQ1 in the maintenance of genomic stability.The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous DNA helicase that preferentially unwinds holliday junctions.Meiotic recombination intermediates are resolved with minimal crossover formation during return-to-growth, an analogue of the mitotic cell cycle Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases.When transcription meets recombination: a lesson from the human RECQ protein complexes Sgs1 and Exo1 suppress targeted chromosome duplication during ends-in and ends-out gene targeting.Recruitment and retention dynamics of RECQL5 at DNA double strand break sites.Recruitment of HRDC domain of WRN and BLM to the sites of DNA damage induced by mitomycin C and methyl methanesulfonate.The dissolution of double Holliday junctions.A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures Characterization of biochemical properties of Bacillus subtilis RecQ helicase Holliday junction processing activity of the BLM-Topo IIIalpha-BLAP75 complex.Sgs1 truncations induce genome rearrangements but suppress detrimental effects of BLM overexpression in Saccharomyces cerevisiae.RMI1 attenuates tumor development and is essential for early embryonic survival The absence of Top3 reveals an interaction between the Sgs1 and Pif1 DNA helicases in Saccharomyces cerevisiae.Sit down, relax and unwind: structural insights into RecQ helicase mechanisms.Template disruptions and failure of double Holliday junction dissolution during double-strand break repair in Drosophila BLM mutants.Roles of type 1A topoisomerases in genome maintenance in Escherichia coli.Prelude to a division RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability.

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The HRDC domain of BLM is required for the dissolution of double Holliday junctions

http://www.wikidata.org/entity/Q33899656

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2005 nî lūn-bûn

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2005 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

The HRDC domain of BLM is required for the dissolution of double Holliday junctions

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The HRDC domain of BLM is required for the dissolution of double Holliday junctions

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type

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The HRDC domain of BLM is required for the dissolution of double Holliday junctions

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The HRDC domain of BLM is required for the dissolution of double Holliday junctions

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prefLabel

The HRDC domain of BLM is required for the dissolution of double Holliday junctions

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The HRDC domain of BLM is required for the dissolution of double Holliday junctions

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SJ.EMBOJ.7600740

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The EMBO Journal

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The HRDC domain of BLM is required for the dissolution of double Holliday junctions

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P2093

Alessandro Vindigni

http://www.w3.org/2001/XMLSchema#string

Christine Ralf

http://www.w3.org/2001/XMLSchema#string

Douglas A Bernstein

http://www.w3.org/2001/XMLSchema#string

Ian D Hickson

http://www.w3.org/2001/XMLSchema#string

James L Keck

http://www.w3.org/2001/XMLSchema#string

Kok Lung Chan

http://www.w3.org/2001/XMLSchema#string

Leonard Wu

http://www.w3.org/2001/XMLSchema#string

Patrick L Garcia

http://www.w3.org/2001/XMLSchema#string

Pavel Janscak

http://www.w3.org/2001/XMLSchema#string

Vilhelm A Bohr

http://www.w3.org/2001/XMLSchema#string

P2860

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

Functional and physical interaction between WRN helicase and human replication protein A

Association of the Bloom syndrome protein with topoisomerase IIIalpha in somatic and meiotic cells

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins

RAD51C is required for Holliday junction processing in mammalian cells

The Bloom's syndrome gene product is a 3'-5' DNA helicase

The Bloom's syndrome gene product is homologous to RecQ helicases

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2679-2687

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scholarly article

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10.1038/SJ.EMBOJ.7600740

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14

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24

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2005-06-30T00:00:00Z

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7752956

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15990871

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1176466

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