Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
about
Quadruplex DNA: sequence, topology and structureHuman POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.Highly prevalent putative quadruplex sequence motifs in human DNAi-motif solution structure and dynamics of the d(AACCCC) and d(CCCCAA) tetrahymena telomeric repeatsOverexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescenceEfficient isothermal expansion of human telomeric and minisatellite repeats by Thermococcus litoralis DNA polymerase.Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeatsStructure, internal motions and association-dissociation kinetics of the i-motif dimer of d(5mCCTCACTCC).The effect of osmolytes and small molecule on Quadruplex-WC duplex equilibrium: a fluorescence resonance energy transfer study.Preferential binding of a G-quadruplex ligand to human chromosome ends.Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb)Resolution of a structural competition involving dimeric G-quadruplex and its C-rich complementary strand.Replication of Structured DNA and its implication in epigenetic stabilityStructure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structuresG-Quadruplexes Involving Both Strands of Genomic DNA Are Highly Abundant and Colocalize with Functional Sites in the Human GenomeTwo-repeat human telomeric d(TAGGGTTAGGGT) sequence forms interconverting parallel and antiparallel G-quadruplexes in solution: distinct topologies, thermodynamic properties, and folding/unfolding kineticsDNA duplex-quadruplex exchange as the basis for a nanomolecular machine.Design of ultrasensitive DNA-based fluorescent pH sensitive nanodevices.Mitoxantrone and Analogues Bind and Stabilize i-Motif Forming DNA Sequences.Human replication protein A melts a DNA triple helix structure in a potent and specific mannerTargeting human telomerase for cancer therapeutics.Pressure-dependent formation of i-motif and G-quadruplex DNA structures.Molecular crowding creates an essential environment for the formation of stable G-quadruplexes in long double-stranded DNACytotoxicity of Pyrazine-Based Cyclometalated (C^Npz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties.Single-molecule TPM studies on the conversion of human telomeric DNAChemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Identification of G-quadruplex structures that possess transcriptional regulating functions in the Dele and Cdc6 CpG islands.Molecular dynamics simulations of Guanine quadruplex loops: advances and force field limitations.Design, synthesis and biological evaluation of a novel class of anticancer agents: anthracenylisoxazole lexitropsin conjugatesG-quadruplex and i-motif are mutually exclusive in ILPR double-stranded DNA.Folding and hydrodynamics of a DNA i-motif from the c-MYC promoter determined by fluorescent cytidine analogs.Simple and convenient G-quadruplex-based turn-on fluorescence assay for 3' → 5' exonuclease activity.Possible regulatory roles of promoter g-quadruplexes in cardiac function-related genes - human TnIc as a model.The role of G-quadruplex/i-motif secondary structures as cis-acting regulatory elements.The PNA-DNA hybrid I-motif: implications for sugar-sugar contacts in i-motif tetramerization.Highly fluorescent guanosine mimics for folding and energy transfer studiesCarboxyl-modified single-walled carbon nanotubes selectively induce human telomeric i-motif formation.A fluorescence-based helicase assay: application to the screening of G-quadruplex ligands.Unfolding Kinetics of the Human Telomere i-Motif Under a 10 pN Force Imposed by the α-Hemolysin Nanopore Identify Transient Folded-State Lifetimes at Physiological pH.A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti-hepatitis C target.
P2860
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P2860
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
description
2002 nî lūn-bûn
@nan
2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
@ast
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
@en
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
@nl
type
label
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
@ast
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
@en
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
@nl
prefLabel
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
@ast
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
@en
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
@nl
P2860
P356
P1476
Human telomeric DNA: G-quadruplex, i-motif and Watson-Crick double helix.
@en
P2093
Anh Tuân Phan
P2860
P304
P356
10.1093/NAR/GKF597
P407
P577
2002-11-01T00:00:00Z