The Bloom's syndrome helicase suppresses crossing over during homologous recombination
about
Controlling meiotic recombinational repair - specifying the roles of ZMMs, Sgs1 and Mus81/Mms4 in crossover formationDifferent quaternary structures of human RECQ1 are associated with its dual enzymatic activityMechanisms of change in gene copy numberBLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repairStructural and functional analyses of disease-causing missense mutations in Bloom syndrome proteinCrystal structures of the structure-selective nuclease Mus81-Eme1 bound to flap DNA substratesRif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replicationBLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrityRECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombinationStimulation of flap endonuclease-1 by the Bloom's syndrome proteinA novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrityHuman topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1Human SLX4 is a Holliday junction resolvase subunit that binds multiple DNA repair/recombination endonucleasesSws1 is a conserved regulator of homologous recombination in eukaryotic cellsHuman GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctionsPolyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stressRecql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers.Identification of RecQL1 as a Holliday junction processing enzyme in human cell linesBLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediatesThe RecQ DNA helicases in DNA repairHuman RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptidePhysical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1Meiotic versus mitotic recombination: two different routes for double-strand break repair: the different functions of meiotic versus mitotic DSB repair are reflected in different pathway usage and different outcomesHomologous recombination in DNA repair and DNA damage toleranceHuman RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biologyHuman pyruvate kinase M2: a multifunctional proteinModel of human aging: recent findings on Werner's and Hutchinson-Gilford progeria syndromesRoles of RECQ helicases in recombination based DNA repair, genomic stability and agingMore complexity to the Bloom's syndrome complexRMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stabilityBLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasomeDNA end resection: many nucleases make light workReconstitution of initial steps of dsDNA break repair by the RecF pathway of E. coliHuman RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication forkRECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filamentsFunctional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrestHuman premature aging, DNA repair and RecQ helicasesStructural and functional characterizations reveal the importance of a zinc binding domain in Bloom's syndrome helicaseThe Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNAArchaeal Hel308 helicase targets replication forks in vivo and in vitro and unwinds lagging strands
P2860
Q21144863-6473D3AC-C2EC-47AB-BB66-5A36BDD2A66DQ21145897-A9A44996-3458-4597-9A2D-8A878FE33F87Q22122003-CB0A91C0-0456-4308-AF33-47A3A754C9FCQ24293244-B4F31B1C-823D-4862-8C9C-CE12BA0C5BB3Q24294274-BC29B7F1-2F2E-4FE8-80F4-F89426ED8BDFQ24294687-5672386E-6ADC-46DF-94DC-D3B8F9807CDFQ24295460-F1BD09B3-3242-47C7-B8B2-79E7CD0C5D4CQ24298321-9776F706-557C-489F-A9BC-D7970B3D84BDQ24301788-33781AF2-A33F-4182-8279-E32B12D3C24BQ24302463-A297FFCA-50C2-4B1D-874B-D16031627510Q24304112-837C0047-8B77-47C5-9016-8D9A5FEB4B9AQ24310243-52ECDB19-6EED-4F38-B11C-322933A770B4Q24314357-C2CB4FEF-C678-4C8A-81DD-489A5076FD8EQ24337352-58A6F49E-21F4-40E8-9E74-20D1C68DE556Q24337537-72C58646-92EF-4B9D-A3EA-FC80A0BAFB27Q24338351-CAAD4780-7F89-4204-A385-A52362500AECQ24522689-5D40DEAA-D954-4AD1-84C3-8188608042C4Q24536291-F2DD7931-49ED-4C3B-B71F-89472F002A56Q24544999-B79F0B0D-6B18-4F6A-8FED-3189FE1704D9Q24561510-49A7386F-3FC4-403E-AEB2-330B85A76E5FQ24563101-E224257E-0731-4C92-B031-08B685C624D9Q24563359-C5572AFB-AD6F-4F3F-BA7C-42E5DA8B9304Q24597411-BCBBF5E9-33A9-443F-93BD-5DFF84F88CA4Q24601150-7023A382-D2D6-403D-860B-68894B682DF1Q24620195-D1E26DFE-76D7-4F53-8680-BAEA18A3DB7AQ24625882-738C0D24-4B20-4E69-B099-21AEB45425CFQ24644033-F9BED21F-A6FE-4F18-BBFE-278F520ACDCAQ24646853-E3662258-5FB7-4875-AB2F-4FDBD7AA25BEQ24647810-216D7EE5-D19A-4393-B6D8-4D8BB731091CQ24650860-33461E53-D7F4-41B8-9D3B-C2C64C180ED8Q24650899-A3DAEFB5-C688-4A1C-85B4-1FB70A5C2C96Q24654725-F0D1ACCA-77CE-41AB-B4B6-5CF8A727B66BQ24657500-C347767B-2DBF-4043-9C12-F7B59511237FQ24674376-72CFC554-0CA5-4BAE-BE9C-0E732AB67585Q24676019-1E2924A0-87D7-412A-974D-6969A86BDD11Q24677047-958B7E4B-6BF3-4C45-A115-AD6DD051B616Q24680996-5EE2DEB5-EBB3-45A1-80AD-B82C218E89E3Q24810234-65C56EF4-F982-48B3-B46F-633D15A56B15Q24812850-2D44BDC4-4C44-48A4-BA87-3F420BC1F287Q24815281-7FAF081A-D7C7-4B4A-AF8C-DCD422E3D729
P2860
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
description
2003 nî lūn-bûn
@nan
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
@ast
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
@en
type
label
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
@ast
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
@en
prefLabel
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
@ast
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
@en
P2860
P3181
P356
P1433
P1476
The Bloom's syndrome helicase suppresses crossing over during homologous recombination
@en
P2860
P2888
P3181
P356
10.1038/NATURE02253
P407
P577
2003-12-18T00:00:00Z
P6179
1028183793