4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesulfonate) (NSC 88915) and related novel steroid derivatives as tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors.
about
Toxicology and drug delivery by cucurbit[n]uril type molecular containersInhibitors of human tyrosyl-DNA phospodiesterase (hTdp1) developed by virtual screening using ligand-based pharmacophores.Design, synthesis, and biological evaluation of O-2-modified indenoisoquinolines as dual topoisomerase I-tyrosyl-DNA phosphodiesterase I inhibitors.Tyrosyl-DNA-phosphodiesterases (TDP1 and TDP2).Biochemical assays for the discovery of TDP1 inhibitorsTyrosyl-DNA Phosphodiesterase 1 (Tdp1) inhibitorsSynthesis and biological evaluation of the first dual tyrosyl-DNA phosphodiesterase I (Tdp1)-topoisomerase I (Top1) inhibitors.Identification of several high-risk HPV inhibitors and drug targets with a novel high-throughput screening assayTyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target.Structure Modeling of Human Tyrosyl-DNA Phosphodiesterase 1 and Screening for Its Inhibitors.Identification of a putative Tdp1 inhibitor (CD00509) by in vitro and cell-based assays.Survey of the 2009 commercial optical biosensor literature.Tyrosyl-DNA phosphodiesterases: rescuing the genome from the risks of relaxation.Structural basis for DNA 3'-end processing by human tyrosyl-DNA phosphodiesterase 1.Identification of Natural Products That Inhibit the Catalytic Function of Human Tyrosyl-DNA Phosphodiesterase (TDP1)
P2860
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P2860
4-Pregnen-21-ol-3,20-dione-21-(4-bromobenzenesulfonate) (NSC 88915) and related novel steroid derivatives as tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors.
description
2009 nî lūn-bûn
@nan
2009年の論文
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2009年学术文章
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2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
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2009年學術文章
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name
4-Pregnen-21-ol-3,20-dione-21- ...... odiesterase (Tdp1) inhibitors.
@en
4-Pregnen-21-ol-3,20-dione-21- ...... odiesterase (Tdp1) inhibitors.
@nl
type
label
4-Pregnen-21-ol-3,20-dione-21- ...... odiesterase (Tdp1) inhibitors.
@en
4-Pregnen-21-ol-3,20-dione-21- ...... odiesterase (Tdp1) inhibitors.
@nl
prefLabel
4-Pregnen-21-ol-3,20-dione-21- ...... odiesterase (Tdp1) inhibitors.
@en
4-Pregnen-21-ol-3,20-dione-21- ...... odiesterase (Tdp1) inhibitors.
@nl
P2093
P2860
P356
P1476
4-Pregnen-21-ol-3,20-dione-21- ...... odiesterase (Tdp1) inhibitors.
@en
P2093
Andrew G Stephen
Christophe Marchand
Heidrun Interthal
Iwona Weidlich
Lalji K Gediya
Marc Nicklaus
Robert J Fisher
Smitha Antony
Thomas S Dexheimer
Vincent C Njar
P2860
P304
P356
10.1021/JM901061S
P407
P50
P577
2009-11-01T00:00:00Z