GPCR agonist binding revealed by modeling and crystallography.
about
Diversity and modularity of G protein-coupled receptor structuresNullspace Sampling with Holonomic Constraints Reveals Molecular Mechanisms of Protein GαsModeling, molecular dynamics simulation, and mutation validation for structure of cannabinoid receptor 2 based on known crystal structures of GPCRs.Computational studies to predict or explain G protein coupled receptor polypharmacologyCurrent progress in Structure-Based Rational Drug Design marks a new mindset in drug discoveryEvaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor.Rescue of misrouted GnRHR mutants reveals its constitutive activityOptimization of adenosine 5'-carboxamide derivatives as adenosine receptor agonists using structure-based ligand design and fragment screening.Probing GPCR structure: adenosine and P2Y nucleotide receptors.Chemotype-selective modes of action of κ-opioid receptor agonists.Computational methods for the discovery of mood disorder therapies.Molecular alliance-from orthosteric and allosteric ligands to dualsteric/bitopic agonists at G protein coupled receptors.The receptor concept in 3D: from hypothesis and metaphor to GPCR-ligand structures.Magnetotactic bacteria for cancer therapy.Magnetotactic bacteria: nanodrivers of the future.Expanding the horizons of G protein-coupled receptor structure-based ligand discovery and optimization using homology models.Detailed analysis of biased histamine H₄ receptor signalling by JNJ 7777120 analogues.G Protein-Coupled Estrogen Receptor (GPER) Agonist Dual Binding Mode Analyses toward Understanding of its Activation Mechanism: A Comparative Homology Modeling ApproachA structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design.Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges.Integrating Pharmacophore into Membrane Molecular Dynamics Simulations to Improve Homology Modeling of G Protein-coupled Receptors with Ligand Selectivity: A2A Adenosine Receptor as an Example.
P2860
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P2860
GPCR agonist binding revealed by modeling and crystallography.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
GPCR agonist binding revealed by modeling and crystallography.
@en
type
label
GPCR agonist binding revealed by modeling and crystallography.
@en
prefLabel
GPCR agonist binding revealed by modeling and crystallography.
@en
P2860
P1476
GPCR agonist binding revealed by modeling and crystallography.
@en
P2860
P304
P356
10.1016/J.TIPS.2011.08.001
P577
2011-09-06T00:00:00Z