about
Deubiquitylating enzymes and diseaseOTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitinSHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosisVHS domains of ESCRT-0 cooperate in high-avidity binding to polyubiquitinated cargoCrystal structure of a Josephin-ubiquitin complex: evolutionary restraints on ataxin-3 deubiquitinating activityK63-specific deubiquitination by two JAMM/MPN+ complexes: BRISC-associated Brcc36 and proteasomal Poh1The ubiquitin ligase Triad1 inhibits myelopoiesis through UbcH7 and Ubc13 interacting domainsRegulation of the stability and transcriptional activity of NFATc4 by ubiquitinationLys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase CezanneThe Structure and Conformation of Lys63-Linked TetraubiquitinCrystal structures of Lys-63-linked tri- and di-ubiquitin reveal a highly extended chain architectureStructure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2Structure of Rpn10 and Its Interactions with Polyubiquitin Chains and the Proteasome Subunit Rpn12Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinaseA conserved asparagine has a structural role in ubiquitin-conjugating enzymesAssembly, analysis and architecture of atypical ubiquitin chainsUnique Structural, Dynamical, and Functional Properties of K11-Linked Polyubiquitin ChainsStructure of parkin reveals mechanisms for ubiquitin ligase activationStructure of the Rpn11-Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradationMode of substrate recognition by the Josephin domain of ataxin-3, which has an endo-type deubiquitinase activitySynthesis of free and proliferating cell nuclear antigen-bound polyubiquitin chains by the RING E3 ubiquitin ligase Rad5.Disassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.Evidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progressionThe Vps27/Hrs/STAM (VHS) Domain of the Signal-transducing Adaptor Molecule (STAM) Directs Associated Molecule with the SH3 Domain of STAM (AMSH) Specificity to Longer Ubiquitin Chains and Dictates the Position of Cleavage.Competitive binding of UBPY and ubiquitin to the STAM2 SH3 domain revealed by NMR.Human DNA-Damage-Inducible 2 Protein Is Structurally and Functionally Distinct from Its Yeast Ortholog.Understanding the role of the Josephin domain in the PolyUb binding and cleavage properties of ataxin-3.Specificity of the BRISC deubiquitinating enzyme is not due to selective binding to Lys63-linked polyubiquitin.Nonenzymatic polymerization of ubiquitin: single-step synthesis and isolation of discrete ubiquitin oligomersThe challenge of producing ubiquitinated proteins for structural studiesNF-κB essential modulator (NEMO) interaction with linear and lys-63 ubiquitin chains contributes to NF-κB activationRNF4-dependent hybrid SUMO-ubiquitin chains are signals for RAP80 and thereby mediate the recruitment of BRCA1 to sites of DNA damage.p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria.Biochemical and structural characterization of the ubiquitin-conjugating enzyme UBE2W reveals the formation of a noncovalent homodimerIntrinsic disorder drives N-terminal ubiquitination by Ube2wProteomic identification and analysis of K63-linked ubiquitin conjugatesgp78 elongates of polyubiquitin chains from the distal end through the cooperation of its G2BR and CUE domainsMolecular determinants of polyubiquitin linkage selection by an HECT ubiquitin ligase.Deubiquitinating enzyme specificity for ubiquitin chain topology profiled by di-ubiquitin activity probes
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Controlled synthesis of polyubiquitin chains.
@en
Controlled synthesis of polyubiquitin chains.
@nl
type
label
Controlled synthesis of polyubiquitin chains.
@en
Controlled synthesis of polyubiquitin chains.
@nl
prefLabel
Controlled synthesis of polyubiquitin chains.
@en
Controlled synthesis of polyubiquitin chains.
@nl
P1476
Controlled synthesis of polyubiquitin chains.
@en
P2093
Cecile M Pickart
Shahri Raasi
P356
10.1016/S0076-6879(05)99002-2
P407
P577
2005-01-01T00:00:00Z