Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition. - Wikidata - wikimedia - TriplyDB

Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition.

Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition.

http://www.wikidata.org/entity/Q37298015

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New insights into sodium transport regulation in the distal nephron: Role of G-protein coupled receptors A peptide-based approach to evaluate the adaptability of influenza A virus to humans based on its hemagglutinin proteolytic cleavage site.Matriptase, HAT, and TMPRSS2 activate the hemagglutinin of H9N2 influenza A viruses.Matriptase proteolytically activates influenza virus and promotes multicycle replication in the human airway epithelium.Local protease signaling contributes to neural tube closure in the mouse embryo Matriptase activation, an early cellular response to acidosis.Matriptase zymogen supports epithelial development, homeostasis and regeneration HIV-1 enhancing effect of prostatic acid phosphatase peptides is reduced in human seminal plasma.Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin.Regulation of the matriptase-prostasin cell surface proteolytic cascade by hepatocyte growth factor activator inhibitor-1 during epidermal differentiation Preferential entry of botulinum neurotoxin A Hc domain through intestinal crypt cells and targeting to cholinergic neurons of the mouse intestine Transport via the transcytotic pathway makes prostasin available as a substrate for matriptase Increased matriptase zymogen activation in inflammatory skin disorders.Antithrombin regulates matriptase activity involved in plasmin generation, syndecan shedding, and HGF activation in keratinocytes.Detection of active matriptase using a biotinylated chloromethyl ketone peptide Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cells Matriptase is inhibited by extravascular antithrombin in epithelial cells but not in most carcinoma cells Matriptase protects against experimental colitis and promotes intestinal barrier recovery Mechanisms for the control of matriptase activity in the absence of sufficient HAI-1 Matriptase Complexes and Prostasin Complexes with HAI-1 and HAI-2 in Human Milk: Significant Proteolysis in Lactation Natural Endogenous Human Matriptase and Prostasin Undergo Zymogen Activation via Independent Mechanisms in an Uncoupled Manner.Cleavage activation of the human-adapted influenza virus subtypes by matriptase reveals both subtype and strain specificities.Hepatocyte growth factor activator inhibitor-2 prevents shedding of matriptase Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway.The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Imbalanced matriptase pericellular proteolysis contributes to the pathogenesis of malignant B-cell lymphomas.Matriptase and prostasin are expressed in human skin in an inverse trend over the course of differentiation and are targeted to different regions of the plasma membrane.Matriptase expression and zymogen activation in human pilosebaceous unit.Matriptase regulates proliferation and early, but not terminal, differentiation of human keratinocytes The matriptase-prostasin proteolytic cascade in epithelial development and pathology.The structural requirements of matriptase in its ectodomain release in polarized epithelial cells.Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity.Roles of CUB and LDL receptor class A domain repeats of a transmembrane serine protease matriptase in its zymogen activation.Identification of the matriptase second CUB domain as the secondary site for interaction with hepatocyte growth factor activator inhibitor type-1.Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin.Intestinal regulation of suppression of tumorigenicity 14 (ST14) and serine peptidase inhibitor, Kunitz type -1 (SPINT1) by transcription factor CDX2

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Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition.

http://www.wikidata.org/entity/Q37298015

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 17 June 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Polarized epithelial cells sec ...... and HAI-1-mediated inhibition.

@en

Polarized epithelial cells sec ...... and HAI-1-mediated inhibition.

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type

label

Polarized epithelial cells sec ...... and HAI-1-mediated inhibition.

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Polarized epithelial cells sec ...... and HAI-1-mediated inhibition.

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prefLabel

Polarized epithelial cells sec ...... and HAI-1-mediated inhibition.

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Polarized epithelial cells sec ...... and HAI-1-mediated inhibition.

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AJPCELL.00201.2009

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American Journal of Physiology - Cell Physiology

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Polarized epithelial cells sec ...... and HAI-1-mediated inhibition.

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Amy Fulton

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Chen-Yong Lin

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Cheng-Jueng Chen

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Feng-Pai Chou

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Herng-Sheng Lee

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I-Chu Tseng

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Jehng-Kang Wang

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Michael D Johnson

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Ming-Shyue Lee

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Ya-Wen Chen

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P2860

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitor

Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo

Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milk

Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease

The activation of matriptase requires its noncatalytic domains, serine protease domain, and its cognate inhibitor

Sphingosine 1-phosphate, present in serum-derived lipoproteins, activates matriptase

Deregulated activation of matriptase in breast cancer cells

Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts

A role for membrane-type serine protease (MT-SP1) in intestinal epithelial turnover

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C459-70

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scholarly article

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10.1152/AJPCELL.00201.2009

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2

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297

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19535514

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