The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.
about
Linking functional decline of telomeres, mitochondria and stem cells during ageingZIP4H (TEX11) deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing overChk2 suppresses the oncogenic potential of DNA replication-associated DNA damageGenetic variation in the NBS1, MRE11, RAD50 and BLM genes and susceptibility to non-Hodgkin lymphoma.Molecular cartography: mapping the landscape of meiotic recombination.No overt nucleosome eviction at deprotected telomeres.Exonuclease 1 is a critical mediator of survival during DNA double strand break repair in nonquiescent hematopoietic stem and progenitor cells.Cdc42 and aging of hematopoietic stem cells.DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesionsStem cell ageing and non-random chromosome segregation.Targeted JAM-C deletion in germ cells by Spo11-controlled Cre recombinase.Tying the loose ends together in DNA double strand break repair with 53BP1.Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis.Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymesFunctional interactions between Sae2 and the Mre11 complex.The cellular response to chromosome breakage.DNA-damage repair; the good, the bad, and the ugly.Defining ATM-Independent Functions of the Mre11 Complex with a Novel Mouse ModelHow does suppression of IGF-1 signaling by DNA damage affect aging and longevity?Antisense inhibition of ATM gene enhances the radiosensitivity of head and neck squamous cell carcinoma in mice.The role of DNA damage repair in aging of adult stem cellsDNA damage response at functional and dysfunctional telomeresMre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.The mre11 complex and the response to dysfunctional telomeres.The MRE11 complex: starting from the ends.The p53 tumor suppressor protein is a critical regulator of hematopoietic stem cell behavior.The Rad50 hook domain regulates DNA damage signaling and tumorigenesis.Making the best of the loose ends: Mre11/Rad50 complexes and Sae2 promote DNA double-strand break resection.The p53 tumor suppressor protein regulates hematopoietic stem cell fate.ATP puts the brake on DNA double-strand break repair: a new study shows that ATP switches the Mre11-Rad50-Nbs1 repair factor between signaling and processing of DNA ends.Generation of a novel, multi-stage, progressive, and transplantable model of plasma cell neoplasms.Loss of homologous recombination or non-homologous end-joining leads to radial formation following DNA interstrand crosslink damage.The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.Mre11 regulates CtIP-dependent double-strand break repair by interaction with CDK2.The mef/elf4 transcription factor fine tunes the DNA damage response.Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2Role of inflammatory cytokines and DNA damage repair proteins in sulfur mustard exposed mice liver.The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways.Ataxia-telangiectasia: A new remitting form with a peculiar transcriptome signature.Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells.
P2860
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P2860
The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.
description
2005 nî lūn-bûn
@nan
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The Rad50S allele promotes ATM ...... omplex as a DNA damage sensor.
@ast
The Rad50S allele promotes ATM ...... omplex as a DNA damage sensor.
@en
The Rad50S allele promotes ATM ...... omplex as a DNA damage sensor.
@nl
type
label
The Rad50S allele promotes ATM ...... omplex as a DNA damage sensor.
@ast
The Rad50S allele promotes ATM ...... omplex as a DNA damage sensor.
@en
The Rad50S allele promotes ATM ...... omplex as a DNA damage sensor.
@nl
prefLabel
The Rad50S allele promotes ATM ...... omplex as a DNA damage sensor.
@ast
The Rad50S allele promotes ATM ...... omplex as a DNA damage sensor.
@en
The Rad50S allele promotes ATM ...... omplex as a DNA damage sensor.
@nl
P2093
P2860
P356
P1433
P1476
The Rad50S allele promotes ATM ...... complex as a DNA damage sensor
@en
P2093
Carla F Bender Kim
Jan-Willem F Theunissen
Michael B Kastan
Monica Morales
Risa Kitagawa
P2860
P304
P356
10.1101/GAD.1373705
P50
P577
2005-12-01T00:00:00Z