RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks
about
FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51Interplay between Fanconi anemia and homologous recombination pathways in genome integrityManaging Single-Stranded DNA during Replication Stress in Fission YeastMechanisms for initiating cellular DNA replicationRescuing stalled or damaged replication forksSources of DNA double-strand breaks and models of recombinational DNA repairComplex chromosomal rearrangements mediated by break-induced replication involve structure-selective endonucleases.Cdc45 protein-single-stranded DNA interaction is important for stalling the helicase during replication stress.Replication stress: getting back on trackReplication fork instability and the consequences of fork collisions from rereplicationPreventing replication fork collapse to maintain genome integrityReplication stress in Mammalian cells and its consequences for mitosisATM and ATR activities maintain replication fork integrity during SV40 chromatin replication.Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication.Is homologous recombination really an error-free process?DNA double-strand break repair genes and oxidative damage in brain metastasis of breast cancer.Recombination and replication.Recovery of arrested replication forks by homologous recombination is error-prone.RAD51B plays an essential role during somatic and meiotic recombination in PhyscomitrellaBRCA1 haploinsufficiency for replication stress suppression in primary cellsThe Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forksThe SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability.Cdc45 (cell division cycle protein 45) guards the gate of the Eukaryote Replisome helicase stabilizing leading strand engagement.DNA2 drives processing and restart of reversed replication forks in human cells.A PCNA-derived cell permeable peptide selectively inhibits neuroblastoma cell growth.Replication fork integrity and intra-S phase checkpoint suppress gene amplification.SV40 utilizes ATM kinase activity to prevent non-homologous end joining of broken viral DNA replication productsCentromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppressionThe Replication Checkpoint Prevents Two Types of Fork Collapse without Regulating Replisome Stability.Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex.Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA ReplicationSafeguarding genome stability: RASSF1A tumor suppressor regulates BRCA2 at stalled forks.Ku Binding on Telomeres Occurs at Sites Distal from the Physical Chromosome EndsRad51 recombinase prevents Mre11 nuclease-dependent degradation and excessive PrimPol-mediated elongation of nascent DNA after UV irradiation.DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network.Reduced cohesin destabilizes high-level gene amplification by disrupting pre-replication complex bindings in human cancers with chromosomal instability.Chromatin-associated degradation is defined by UBXN-3/FAF1 to safeguard DNA replication fork progression.Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling.High levels of RAD51 perturb DNA replication elongation and cause unscheduled origin firing due to impaired CHK1 activation.Structure of human Cdc45 and implications for CMG helicase function
P2860
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P2860
RAD51- and MRE11-dependent reassembly of uncoupled CMG helicase complex at collapsed replication forks
description
2011 nî lūn-bûn
@nan
2011 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
RAD51- and MRE11-dependent rea ...... at collapsed replication forks
@ast
RAD51- and MRE11-dependent rea ...... at collapsed replication forks
@en
type
label
RAD51- and MRE11-dependent rea ...... at collapsed replication forks
@ast
RAD51- and MRE11-dependent rea ...... at collapsed replication forks
@en
prefLabel
RAD51- and MRE11-dependent rea ...... at collapsed replication forks
@ast
RAD51- and MRE11-dependent rea ...... at collapsed replication forks
@en
P2860
P356
P1476
RAD51- and MRE11-dependent rea ...... at collapsed replication forks
@en
P2093
Yoshitami Hashimoto
P2860
P2888
P356
10.1038/NSMB.2177
P577
2011-12-04T00:00:00Z