Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination. - Wikidata - wikimedia - TriplyDB

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

http://www.wikidata.org/entity/Q36229482

about

Alternative end-joining mechanisms: a historical perspective Ku regulates the non-homologous end joining pathway choice of DNA double-strand break repair in human somatic cells The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway Related Mechanisms of Antibody Somatic Hypermutation and Class Switch Recombination Flexibility in the order of action and in the enzymology of the nuclease, polymerases, and ligase of vertebrate non-homologous DNA end joining: relevance to cancer, aging, and the immune system Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunity Double strand break repair functions of histone H2AX Role of mammalian Mre11 in classical and alternative nonhomologous end joining MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings Molecular characterization of hybridoma subclones spontaneously switching at high frequencies in vitro.RAG2's acidic hinge restricts repair-pathway choice and promotes genomic stability.The Mre11/Rad50/Nbs1 complex functions in resection-based DNA end joining in Xenopus laevis Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination.Origin of chromosomal translocations in lymphoid cancer.Mechanisms promoting translocations in editing and switching peripheral B cells.Radiosensitive severe combined immunodeficiency disease.Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair.The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies.Mechanisms of double-strand break repair in somatic mammalian cells.Chromatin remodeling, DNA damage repair and aging.Impaired induction of DNA lesions during immunoglobulin class-switch recombination in humans influences end-joining repair.ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining Mechanism and regulation of class switch recombination Mismatch repair proteins MSH2, MLH1, and EXO1 are important for class-switch recombination events occurring in B cells that lack nonhomologous end joining.Choosing the right path: does DNA-PK help make the decision?Human Mre11/human Rad50/Nbs1 and DNA ligase IIIalpha/XRCC1 protein complexes act together in an alternative nonhomologous end joining pathway XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining in Igh genes.Identification of novel radiosensitizers in a high-throughput, cell-based screen for DSB repair inhibitors.X-ray repair cross-complementing protein 1 (XRCC1) deficiency enhances class switch recombination and is permissive for alternative end joining.53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.Initiation of DNA double strand break repair: signaling and single-stranded resection dictate the choice between homologous recombination, non-homologous end-joining and alternative end-joining Terminal deoxynucleotidyl transferase requires KU80 and XRCC4 to promote N-addition at non-V(D)J chromosomal breaks in non-lymphoid cells CtIP promotes microhomology-mediated alternative end joining during class-switch recombination CSReport: A New Computational Tool Designed for Automatic Analysis of Class Switch Recombination Junctions Sequenced by High-Throughput Sequencing.Alternative endings.DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination Immunoglobulin class-switch DNA recombination: induction, targeting and beyond.Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination.Cernunnos deficiency reduces thymocyte life span and alters the T cell repertoire in mice and humans.

P2860

Q21131241-61C4C6F1-1C96-4484-801F-C4D862120C0D Q21563320-04B69A37-41F2-4FF3-8EEB-DC8E6319C68F Q22065419-B00140FB-0357-4106-A43B-828883CD5F50 Q27000758-23B44EC9-BA55-4A56-AECB-9D115D2146FD Q28261381-C076BCB0-58BD-42D5-B189-D83228152647 Q28594927-0EE02F98-9F4F-41AB-9EB9-2ECFB710D58E Q28661754-D6A58A6E-7F93-4202-A99F-1524D3CF9DD1 Q28751872-04ADE783-CCF1-4436-ADF1-0FC3E358E41D Q29614424-A1219437-4D41-4884-95D3-DE6D9072D623 Q33484497-2989A66B-4DB5-4181-B959-941290CE7034 Q33558920-783AC846-4FD4-461E-A53B-0412BDA51957 Q33608866-0D1EB5D7-AB67-4138-A593-60BCBDC5C714 Q33656097-58C83C4B-D1B9-4958-B81A-7D97BBF6867A Q33794964-2A22E15B-E563-4ACB-962E-F791E8FEA496 Q33870612-14080D12-2925-4CEA-9268-6244B393B370 Q34008189-C3A1698B-5DB0-4B30-966D-AF5BCE3747F8 Q34095701-419825F3-A4AC-43BA-A8E2-2A06389F3331 Q34115234-62D626CE-0B27-46F8-AA9C-A9772758B213 Q34189234-58E50CCC-5901-4AB4-BF58-CAF2714656BC Q34317108-3316ABCE-AA7B-46E8-8774-B42DA022C4E3 Q34342179-8352ACA8-587E-4D0C-B507-56897AFFB3C1 Q34438294-FA612801-B0A1-4FA2-A55C-66C610097D6F Q34582166-AE983B9D-890F-46E4-A05A-23F1999BFF9B Q34764888-FBB5051F-0570-4EEC-8A7D-5CE592883616 Q34773522-11276BCC-DE67-40B5-B3BB-E0CA069E00C7 Q35029335-BDBD39E1-73E2-44E7-9209-4F3925B8FFD6 Q35311235-E13E8B5D-411C-4244-B455-D19E9B41F0E3 Q35441496-60D3C6B5-D69D-4770-9B17-0D7DC79ED643 Q35523975-A246AD67-C864-4307-95E5-9F7BCDBF3944 Q35849574-C28A9BE3-95E8-4DA4-9B00-25150DED2160 Q35894239-FB9A64C9-AE65-4AC9-933A-A2C04503AEAA Q36003205-92190103-0F61-449C-85AF-BD5E639E713C Q36280649-A1BE85B1-5F89-4814-8EFC-F0D414F043E8 Q36316904-0F3472B9-6F3D-4828-8696-07A0A951EE1C Q36349107-62469F61-5462-43B5-B98D-7A7C4BA48AFE Q36392830-FC42B828-0741-46A7-A877-844381EC6D0A Q36509842-C8815CC6-6863-4544-8436-4B48B9B4E194 Q36534234-75CCCAC0-E2D1-43C8-8EE5-2E96A1AFEBDD Q36563216-C50C93BD-8FF8-4F70-A5A9-A07FB658C31E Q36606978-3ADF1759-716F-4912-A64D-AE10C7FD772E

P2860

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

http://www.wikidata.org/entity/Q36229482

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

2007年论文

@zh

2007年论文

@zh-cn

name

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

@ast

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

@en

type

label

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

@ast

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

@en

prefLabel

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

@ast

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination.

@en

P1433

Q36229482-35614150-06B2-4EB2-9D72-C91A8458DDAE

P1476

Q36229482-89ADCA0D-8D46-45E4-82BF-BDD57DDDDFC1

P2093

Q36229482-46DBA495-605C-4EF0-AD84-1D612D3F69A5

Q36229482-52C0A92A-5E96-4A54-99A4-9690BEEB7B8F

Q36229482-5B0BBF71-4508-4465-A1E4-D99343F91D8F

Q36229482-612A721B-7454-47E4-BAA3-24A5DFA32455

Q36229482-997ABC81-D419-4392-800E-E99AE0244874

Q36229482-E85548D5-CCB6-4DE7-BA31-E53F7E4AFA6E

P2860

Q36229482-00C63874-7C13-4A92-86CB-8ED2AB5950FC

Q36229482-03521900-67B6-4D30-8431-855EEA367B7A

Q36229482-0E263388-866E-46DD-8A40-12A87F93AAA7

Q36229482-1750E8B1-B1F8-4BD1-9BC6-8348CD8A7190

Q36229482-1DC2CC78-120A-4FD5-B24F-D136C465DE49

Q36229482-1E701366-4B02-4260-8301-317A565E52E6

Q36229482-2A73D8D8-22D1-4F39-889D-D83BD1E8D284

Q36229482-2C622E89-02A7-4625-BB30-0E4EF13CB9C1

Q36229482-2DC13EEC-AFC2-4EF3-88E7-C7B4EF5F5520

Q36229482-31A8B2D2-FEA9-44EE-B7A0-14FB31380D3D

P304

Q36229482-6671ED93-A155-4B95-8D76-C69113F9FCF9

P31

Q36229482-7472A36B-ECA1-4DAD-8E81-A38C3ED4E975

P356

Q36229482-38E98AB8-774E-4D99-B936-364287B028FC

P407

Q36229482-9C3FB0A3-DA35-4C8E-9BA8-B8B7986EE69A

P433

Q36229482-8B16A2CF-4B37-4335-A184-C5EA21C5C625

P478

Q36229482-7D33BA0C-25B1-4D6E-B983-76366422391B

P50

Q36229482-08B43F69-F1D2-4531-89E3-BECE8900DD6D

Q36229482-DAB05316-57C0-48FC-8263-04573A9F288C

P577

Q36229482-2207141F-5585-4E4B-B1FD-56914F61C3C8

P5875

Q36229482-9A297C96-A993-4DB1-8893-6CF2E382835B

P698

Q36229482-2F31E582-45BA-410B-BBC8-221F7192E2DA

P932

Q36229482-E5808F45-DBAC-4D92-BFD1-FDB7CC3BD852

P356

P1433

Journal of Experimental Medicine

P1476

Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination

@en

P2093

Christelle Olivier-Martin

http://www.w3.org/2001/XMLSchema#string

Cécile Goujet-Zalc

http://www.w3.org/2001/XMLSchema#string

Gwenaël Le Guyader

http://www.w3.org/2001/XMLSchema#string

Paola Rivera-Munoz

http://www.w3.org/2001/XMLSchema#string

Pierre Charneau

http://www.w3.org/2001/XMLSchema#string

Vincent Abramowski

http://www.w3.org/2001/XMLSchema#string

P2860

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

Immunoglobulin class switch recombination is impaired in Atm-deficient mice

B cell differentiation and isotype switching is related to division cycle number

A generic protein purification method for protein complex characterization and proteome exploration

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

P304

1717-1727

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.20070255

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

204

http://www.w3.org/2001/XMLSchema#string

P50

Jean-Pierre de Villartay

Pauline Soulas-Sprauel

P577

2007-07-02T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6230377

http://www.w3.org/2001/XMLSchema#string

P698

17606631

http://www.w3.org/2001/XMLSchema#string

P932

2118634

http://www.w3.org/2001/XMLSchema#string