about
Characterization of a novel proapoptotic caspase-2- and caspase-9-binding proteinFGD2, a CDC42-specific exchange factor expressed by antigen-presenting cells, localizes to early endosomes and active membrane rufflesConstruction and characterization of single-chain variable fragment antibody library derived from germline rearranged immunoglobulin variable genesHumanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1Kinetic modeling reveals a common death niche for newly formed and mature B cellsDecoration of T-independent antigen with ligands for CD22 and Siglec-G can suppress immunity and induce B cell tolerance in vivoApotosis of mature B cells.Mixed chimerism induced without lethal conditioning prevents T cell- and anti-Gal alpha 1,3Gal-mediated graft rejectionPeripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen.Suppression of IgE B cells and IgE binding to Fc(epsilon)RI by gene therapy with single-chain anti-IgE.B cell development in mice that lack one or both immunoglobulin kappa light chain genes.B-lymphocyte homeostasis and BLyS-directed immunotherapy in transplantation.Molecular mechanisms for apoptosis induced by signaling through the B cell antigen receptor.Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing.Role of antibody and T cells in the long-term inhibition of IgE synthesis.B cell tolerance to xenoantigens.A B-cell receptor-specific selection step governs immature to mature B cell differentiationDifferent sensitivity to receptor editing of B cells from mice hemizygous or homozygous for targeted Ig transgenesB cell receptor expression level determines the fate of developing B lymphocytes: receptor editing versus selection.Development of human antibody variable genes in systemic autoimmunity.Negative selection by IgM superantigen defines a B cell central tolerance compartment and reveals mutations allowing escapeB cells in autoimmune diabetesAlternative routes to maturity: branch points and pathways for generating follicular and marginal zone B cells.Regulation of the B cell receptor repertoire and self-reactivity by BAFFPeripheral deletion of mature alloreactive B cells induced by costimulation blockade.V(D)J recombinase induction in splenic B lymphocytes is inhibited by antigen-receptor signallingInnate pathways to B-cell activation and tolerance.Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen.B cell abnormality and autoimmune disorders.Receptor editing in self-reactive bone marrow B cells.Human immunoglobulin (IgG) induced deletion of IgM rheumatoid factor B cells in transgenic mice.Light chain replacement: a new model for antibody gene rearrangementThe fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen.Positive selection of anti-thy-1 autoreactive B-1 cells and natural serum autoantibody production independent from bone marrow B cell developmentVisualization of the genesis and fate of isotype-switched B cells during a primary immune responseLoss of the pro-apoptotic BH3-only Bcl-2 family member Bim inhibits BCR stimulation-induced apoptosis and deletion of autoreactive B cells.Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells.Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells.
P2860
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P2860
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
Peripheral deletion of self-reactive B cells.
@en
Peripheral deletion of self-reactive B cells.
@nl
type
label
Peripheral deletion of self-reactive B cells.
@en
Peripheral deletion of self-reactive B cells.
@nl
prefLabel
Peripheral deletion of self-reactive B cells.
@en
Peripheral deletion of self-reactive B cells.
@nl
P2093
P2860
P356
P1433
P1476
Peripheral deletion of self-reactive B cells.
@en
P2093
P2860
P2888
P304
P356
10.1038/354308A0
P407
P577
1991-11-01T00:00:00Z
P6179
1006692018