Thymic depletion and peripheral activation of class I major histocompatibility complex-restricted T cells by soluble peptide in T-cell receptor transgenic mice.
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New approaches to eliciting protective immunity through T cell repertoire manipulation: the concept of thymic vaccinationElimination of self-reactive T cells in the thymus: a timeline for negative selectionTranscriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptorQuantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development.Dendritic cell migration limits the duration of CD8+ T-cell priming to peripheral viral antigen.Perforin and Fas cytolytic pathways coordinately shape the selection and diversity of CD8+-T-cell escape variants of influenza virus.Replication allows inactivation of a knocked-in locus control region in inappropriate cell lineages.T cell-specific inhibition of multiple apoptotic pathways blocks negative selection and causes autoimmunityProbabilistic modeling of rosette formation.Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition.Loss of transcription factor nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) leads to dysregulation of immune functions, redox homeostasis, and intracellular signaling in dendritic cellsInteractions with multiple peptide ligands determine the fate of developing thymocytes.Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes.High- and low-affinity single-peptide/MHC ligands have distinct effects on the development of mucosal CD8alphaalpha and CD8alphabeta T lymphocytesMechanisms of tolerance induction in major histocompatibility complex class II-restricted T cells specific for a blood-borne self-antigen.Bad can act as a key regulator of T cell apoptosis and T cell development.Glucocorticoids attenuate T cell receptor signaling.L-selectin shedding does not regulate constitutive T cell trafficking but controls the migration pathways of antigen-activated T lymphocytes.Resting memory CD8+ T cells are hyperreactive to antigenic challenge in vitro.Tumor rejection induced by CD70-mediated quantitative and qualitative effects on effector CD8+ T cell formation.Contribution of virus-specific CD8+ cytotoxic T cells to virus clearance or pathologic manifestations of influenza virus infection in a T cell receptor transgenic mouse model.The action of Bax and bcl-2 on T cell selectionViral escape by selection of cytotoxic T cell-resistant variants in influenza A virus pneumonia.The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM SensitivityT cell receptor contact to restricting MHC molecules is a prerequisite for peripheral interclonal T cell competition.Coreceptor affinity for MHC defines peptide specificity requirements for TCR interaction with coagonist peptide-MHC.Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals.Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis.The lymph self-antigen repertoire.Heme oxygenase-1 regulates dendritic cell function through modulation of p38 MAPK-CREB/ATF1 signaling.CD8+ T cell tolerance and autoimmunity to extra-thymic antigens.Immunostimulatory bacterial DNA sequences activate dendritic cells and promote priming and differentiation of CD8+ T cells.Differential polarization of C-terminal Src kinase between naive and antigen-experienced CD8+ T cells.Nuclear factor-erythroid 2 (NF-E2) p45-related factor-2 (Nrf2) modulates dendritic cell immune function through regulation of p38 MAPK-cAMP-responsive element binding protein/activating transcription factor 1 signaling.Peptide-major histocompatibility complex dimensions control proximal kinase-phosphatase balance during T cell activationBlocked negative selection of developing T cells in mice expressing the baculovirus p35 caspase inhibitor.Chronic deletion, escape from deletion and activation of mouse mammary tumor virus superantigen-reactive T cells in C57BL/10 mice.Generation of transgenic mice expressing EGFP protein fused to NP68 MHC class I epitope using lentivirus vectors.Exacerbated inflammatory responses in transgenic mice expressing an inhibitor of apoptosis protein (OpIAP).T inflammatory memory CD8 T cells participate to antiviral response and generate secondary memory cells with an advantage in XCL1 production.
P2860
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P2860
Thymic depletion and peripheral activation of class I major histocompatibility complex-restricted T cells by soluble peptide in T-cell receptor transgenic mice.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1992
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Thymic depletion and periphera ...... cell receptor transgenic mice.
@en
Thymic depletion and periphera ...... cell receptor transgenic mice.
@nl
type
label
Thymic depletion and periphera ...... cell receptor transgenic mice.
@en
Thymic depletion and periphera ...... cell receptor transgenic mice.
@nl
prefLabel
Thymic depletion and periphera ...... cell receptor transgenic mice.
@en
Thymic depletion and periphera ...... cell receptor transgenic mice.
@nl
P2093
P2860
P356
P1476
Thymic depletion and periphera ...... cell receptor transgenic mice.
@en
P2093
Chandler P
Kioussis D
Mamalaki C
Townsend AR
P2860
P304
11342-11346
P356
10.1073/PNAS.89.23.11342
P407
P577
1992-12-01T00:00:00Z