Trapping HIV-1 reverse transcriptase before and after translocation on DNA. - Wikidata - wikimedia - TriplyDB

Trapping HIV-1 reverse transcriptase before and after translocation on DNA.

Trapping HIV-1 reverse transcriptase before and after translocation on DNA.

http://www.wikidata.org/entity/Q38358259

about

Structural basis of HIV-1 resistance to AZT by excision Pyrophosphorolytic Excision of Nonobligate Chain Terminators by Hepatitis C Virus NS5B Polymerase Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design Structural Basis for the Role of the K65R Mutation in HIV-1 Reverse Transcriptase Polymerization, Excision Antagonism, and Tenofovir Resistance Structural and Inhibition Studies of the RNase H Function of Xenotropic Murine Leukemia Virus-Related Virus Reverse Transcriptase HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism Structures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavage HIV-1 RT Inhibitors with a Novel Mechanism of Action: NNRTIs that Compete with the Nucleotide Substrate FASTDXL: a generalized screen to trap disulfide-stabilized complexes for use in structural studies Kinetic pathway of pyrophosphorolysis by a retrotransposon reverse transcriptase.4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) inhibits HIV-1 reverse transcriptase with multiple mechanisms HIV-1 Ribonuclease H: Structure, Catalytic Mechanism and Inhibitors.Drug resistance in non-B subtype HIV-1: impact of HIV-1 reverse transcriptase inhibitors.Structures of reverse transcriptase pre- and post-excision complexes shed new light on HIV-1 AZT resistance Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir Effect of translocation defective reverse transcriptase inhibitors on the activity of N348I, a connection subdomain drug resistant HIV-1 reverse transcriptase mutant.NTP-mediated nucleotide excision activity of hepatitis C virus RNA-dependent RNA polymerase.Formation of a quaternary complex of HIV-1 reverse transcriptase with a nucleotide-competing inhibitor and its ATP enhancer.Hypersusceptibility mechanism of Tenofovir-resistant HIV to EFdA.Dissecting APOBEC3G substrate specificity by nucleoside analog interference.Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA)Mechanism of inhibition of HIV-1 reverse transcriptase by 4'-Ethynyl-2-fluoro-2'-deoxyadenosine triphosphate, a translocation-defective reverse transcriptase inhibitor.The kinetic and chemical mechanism of high-fidelity DNA polymerases.The pyrophosphate analogue foscarnet traps the pre-translocational state of HIV-1 reverse transcriptase in a Brownian ratchet model of polymerase translocation.Molecular mechanisms of tenofovir resistance conferred by human immunodeficiency virus type 1 reverse transcriptase containing a diserine insertion after residue 69 and multiple thymidine analog-associated mutations.Rate-limiting Pyrophosphate Release by HIV Reverse Transcriptase Improves Fidelity.Structural Aspects of Drug Resistance and Inhibition of HIV-1 Reverse Transcriptase.Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance.Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet.Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms.Derivatives of mesoxalic acid block translocation of HIV-1 reverse transcriptase.Synthesis and SARs of indole-based α-amino acids as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.Purification, crystallization and preliminary X-ray diffraction of a disulfide cross-linked complex between bovine poly(A) polymerase and a chemically modified 15-mer oligo(A) RNA.Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir.Effects of primer-template sequence on ATP-dependent removal of chain-terminating nucleotide analogues by HIV-1 reverse transcriptase.Site-specific footprinting reveals differences in the translocation status of HIV-1 reverse transcriptase. Implications for polymerase translocation and drug resistance.Site-specific dual-color labeling of long RNAs for single-molecule spectroscopy.Structural requirements for RNA degradation by HIV-1 reverse transcriptase.

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P2860

Trapping HIV-1 reverse transcriptase before and after translocation on DNA.

http://www.wikidata.org/entity/Q38358259

description

2003 nî lūn-bûn

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2003年の論文

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年学术文章

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2003年學術文章

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2003年學術文章

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2003年學術文章

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name

Trapping HIV-1 reverse transcriptase before and after translocation on DNA.

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type

label

Trapping HIV-1 reverse transcriptase before and after translocation on DNA.

@en

prefLabel

Trapping HIV-1 reverse transcriptase before and after translocation on DNA.

@en

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P1433

Journal of Biological Chemistry

P1476

Trapping HIV-1 reverse transcriptase before and after translocation on DNA.

@en

P2093

Andagar R Ramesha

http://www.w3.org/2001/XMLSchema#string

Arthur D Clark

http://www.w3.org/2001/XMLSchema#string

Dequan Sheng

http://www.w3.org/2001/XMLSchema#string

Donald M Jerina

http://www.w3.org/2001/XMLSchema#string

Eddy Arnold

http://www.w3.org/2001/XMLSchema#string

Heiko Kroth

http://www.w3.org/2001/XMLSchema#string

Jane M Sayer

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Palanichamy Ilankumaran

http://www.w3.org/2001/XMLSchema#string

Paul L Boyer

http://www.w3.org/2001/XMLSchema#string

Steve Tuske

http://www.w3.org/2001/XMLSchema#string

P2860

Selective excision of AZTMP by drug-resistant human immunodeficiency virus reverse transcriptase

Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA

Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids

Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA.

Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution

Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA

Cross-linking of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase to template-primer

The M184V mutation reduces the selective excision of zidovudine 5'-monophosphate (AZTMP) by the reverse transcriptase of human immunodeficiency virus type 1

P304

16280-16288

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scholarly article

P356

10.1074/JBC.M212911200

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P433

18

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P478

278

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P50

Stefan G. Sarafianos

Christopher J Squire

Stephen H. Hughes

P577

2003-01-28T00:00:00Z

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12554739

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