Aging and cancer: the double-edged sword of replicative senescence.
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Overexpression of eIF-5A2 in mice causes accelerated organismal aging by increasing chromosome instabilityOn evolutionary origin of cancerDeletion of Ku86 causes early onset of senescence in miceCardiovascular aging research: the next horizons.Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging.Flow cytometric measurement of telomere length.Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor.Analysis of ku80-mutant mice and cells with deficient levels of p53Cancer as a programmed death of an organism.Creation of psoriatic plaques: the ultimate tumor suppressor pathway. A new model for an ancient T-cell-mediated skin disease. Viewpoint.Regulation of cellular senescence by p53.Total deletion of in vivo telomere elongation capacity: an ambitious but possibly ultimate cure for all age-related human cancers.Escherichia coli producing colibactin triggers premature and transmissible senescence in mammalian cells.Targeting of DNA Damage Signaling Pathway Induced Senescence and Reduced Migration of Cancer cells.Cell senescence in human aging and disease.The genetics of exceptional human longevity.Cellular senescence and tissue aging in vivo.Does p53 affect organismal aging?Chondrocyte senescence and telomere regulation: implications in cartilage aging and cancer (a brief review).Senescence-secreted factors activate Myc and sensitize pretransformed cells to TRAIL-induced apoptosis.The proinflammatory phenotype of senescent cells: the p53-mediated ICAM-1 expression.Oxidative stress in aging human skin.CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth.Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.DNA double-strand breaks: a potential causative factor for mammalian aging?Cellular senescence, ageing and diseaseRoles of eukaryotic initiation factor 5A2 in human cancer.Novel pathways associated with bypassing cellular senescence in human prostate epithelial cells.Over-expression of insulin-like growth factor binding protein-related protein-1(IGFBP-rP1/mac25) in the M12 prostate cancer cell line alters tumor growth by a delay in G1 and cyclin A associated apoptosis.When will the biology of aging become useful? Future landmarks in biomedical gerontology.Analysis of cyclin-dependent kinase inhibitor expression and methylation patterns in human prostate cancers.Breathing to younger skin: 'reversing the molecular mechanism of skin aging with yoga'Resistance of primary cultured mouse hepatic tumor cells to cellular senescence despite expression of p16(Ink4a), p19(Arf), p53, and p21(Waf1/Cip1).p16 expression in psoriatic lesions following therapy with propylthiouracil, an antithyroid thioureylene.Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts.The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy.Intercellular competition and the inevitability of multicellular aging.Can biogerontologists and geriatricians unite to apply aging science to health care in the decade ahead?
P2860
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P2860
Aging and cancer: the double-edged sword of replicative senescence.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Aging and cancer: the double-edged sword of replicative senescence.
@en
type
label
Aging and cancer: the double-edged sword of replicative senescence.
@en
prefLabel
Aging and cancer: the double-edged sword of replicative senescence.
@en
P2860
P1476
Aging and cancer: the double-edged sword of replicative senescence.
@en
P2093
P2860
P304
P356
10.1111/J.1532-5415.1997.TB05175.X
P407
P577
1997-04-01T00:00:00Z