mTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression. - Wikidata - wikimedia - TriplyDB

mTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression.

mTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression.

http://www.wikidata.org/entity/Q42793655

about

Shedding new light on neurodegenerative diseases through the mammalian target of rapamycin Pannexin 1 is required for full activation of insulin-stimulated glucose uptake in adipocytes.(Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose.Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.Long-term mTOR inhibitors administration evokes altered calcium homeostasis and platelet dysfunction in kidney transplant patients.Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).Growing knowledge of the mTOR signaling network.Autophagy activation by rapamycin reduces severity of experimental osteoarthritis.Interaction of polyamines and mTOR signaling in the synthesis of antizyme (AZ).Influence of partial and complete glutamine-and glucose deprivation of breast-and cervical tumorigenic cell lines.Metformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation.Sustained activation of mTORC1 in macrophages increases AMPKα-dependent autophagy to maintain cellular homeostasis Survival by self-destruction: a role for autophagy in the placenta?Mammalian target of rapamycin signaling in diabetic cardiovascular disease Neuritic complexity of hippocampal neurons depends on WIP-mediated mTORC1 and Abl family kinases activities A Critical Kinase Cascade in Neurological Disorders: PI 3-K, Akt, and mTOR.Transforming Growth Factor-β1 Induced Epithelial Mesenchymal Transition is blocked by a chemical antagonist of translation factor eIF4E Stimulatory effect of insulin on theca-interstitial cell proliferation and cell cycle regulatory proteins through MTORC1 dependent pathway.Estradiol-induced object recognition memory consolidation is dependent on activation of mTOR signaling in the dorsal hippocampus TDRG1 regulates chemosensitivity of seminoma TCam-2 cells to cisplatin via PI3K/Akt/mTOR signaling pathway and mitochondria-mediated apoptotic pathway.Pegylated IFN-α suppresses hepatitis C virus by promoting the DAPK-mTOR pathway.mTOR function and therapeutic targeting in breast cancer.Mammalian TOR signaling to the AGC kinases.The many roles of the highly interactive HSV protein ICP27, a key regulator of infection.Role of PRAS40 in Akt and mTOR signaling in health and disease.Regulation of mRNA translation by signaling pathways The role of mechanistic target of rapamycin (mTOR) complexes signaling in the immune responses.Axonal protein synthesis and the regulation of primary afferent function Mammalian target of rapamycin inhibition in hepatocellular carcinoma.Mesoglycan attenuates VSMC proliferation through activation of AMP-activated protein kinase and mTOR.MiR-15a/16 deficiency enhances anti-tumor immunity of glioma-infiltrating CD8+ T cells through targeting mTOR.Inhibition of mTOR promotes hyperthermia sensitivity in SMMC-7721 human hepatocellular carcinoma cell line.Ethanolamine enhances the proliferation of intestinal epithelial cells via the mTOR signaling pathway and mitochondrial function.Considerations on mTOR regulation at serine 2448: implications for muscle metabolism studies.Host cell mTORC1 is required for HCV RNA replication.Silencing of tuberin enhances photoreceptor survival and function in a preclinical model of retinitis pigmentosa (an american ophthalmological society thesis).Autophagy is required for G₁/G₀ quiescence in response to nitrogen starvation in Saccharomyces cerevisiae.TSC loss distorts DNA replication programme and sensitises cells to genotoxic stress Rapamycin-induced autophagy activity promotes bone fracture healing in rats.Merging high-quality biochemical fractionation with a refined flow cytometry approach to monitor nucleocytoplasmic protein expression throughout the unperturbed mammalian cell cycle.

P2860

Q27015640-DF441763-4C7C-46AD-B10E-648D4162A1E0 Q30278610-3F220004-B508-4235-8E6B-9A66901D0CDD Q30279173-C720DD01-AD00-43B2-9921-F94034007052 Q30420049-9D5C8E26-6447-4951-A6B3-96F083A31C0B Q33407003-D2C0A306-6DE2-4A18-B1DE-23B4EA95E956 Q34139142-A675FA03-0F5E-48F4-9C17-A61434D23E03 Q34620724-0362815F-ACC0-4C86-986E-7F0AD0DE0858 Q35803625-BDBB3F04-B4E9-4D18-A8EC-672C1C25A502 Q35853765-64E634D1-3DDC-4CC2-B6B7-6AF0A2F1C072 Q35899291-FC816506-CC20-4DCC-BD4E-D5CB6EAE72CC Q35954892-681E7A57-D201-4841-BA80-53DD1D9DB9C9 Q36069782-CE38A7E7-A999-4CAF-A7A0-B7675AAD143C Q36074298-B210FB13-08FB-4188-9661-AAAF0B5B89C2 Q36100715-D2177F2E-3C2E-4A0B-AA58-B1D30F402B4A Q36341800-AAAAB7E1-F2A6-41D8-8676-527BB4D28991 Q36379761-4B7B6232-A52C-4FAD-A000-007189EE725D Q36382304-D08A27E9-379C-4967-BD39-1A26CAE5F057 Q36553215-2051D1AC-5208-4A35-B833-112EFB6330B8 Q36626391-5D323C37-7DC8-4E50-A3B3-DC08DE0C222D Q37146304-0B588BFE-4133-49A7-9A0A-AA46D775BE3B Q37534152-BA18F2A1-9BD5-44C7-958C-0FCC93343C9A Q37743486-296E118C-1884-426B-97A5-36CAABEADA07 Q37943416-3A08639D-F412-4F0C-9278-0BEFA8D1E263 Q37955947-B693868D-406D-40F5-B668-33F9E2C0A86C Q37987085-B9BC612A-8D9C-4E00-A634-B10AE141B24A Q38034202-488C4642-5E3F-436A-9302-5FF8318051FD Q38115702-5B083B18-7067-4834-83DC-C63F4CB2FDCF Q38148485-60090225-0CC6-4FB3-9852-EBF0CEF3CB29 Q38271964-749F52F2-99AA-4084-950B-B787303E82C1 Q38368556-EE9BFA2A-BA9E-4CCE-9EAA-0DD0BA50043B Q38652482-3AB51793-1AE3-407F-BA81-8F3498E1C0DA Q38718383-6F7AA86E-9FF3-4859-AF36-4BF9B9681FDF Q38777866-0DFFC7F2-4771-4C5E-B50C-F5041D4519D9 Q39144817-B9EBAD76-2034-4AF8-8152-FFE16DCF0327 Q41050660-CF0ECF3F-E113-40F0-9947-B7C7FA2125CD Q41488499-5C46FC5F-040C-47DF-B4AA-D3354A5F7A2F Q42121827-5012C548-D100-4E14-8180-5F806B6C9E44 Q42216553-4DFF9344-CF02-47A6-B25C-69CF6742CDAA Q43244262-DC3D18B6-0A97-4B14-B8F2-C08BC074C737 Q43416808-F6519314-5F29-494D-B98A-B1AA1D2992F2

P2860

mTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression.

http://www.wikidata.org/entity/Q42793655

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

mTOR kinase domain phosphoryla ...... h, and cell cycle progression.

@en

mTOR kinase domain phosphoryla ...... h, and cell cycle progression.

@nl

type

label

mTOR kinase domain phosphoryla ...... h, and cell cycle progression.

@en

mTOR kinase domain phosphoryla ...... h, and cell cycle progression.

@nl

prefLabel

mTOR kinase domain phosphoryla ...... h, and cell cycle progression.

@en

mTOR kinase domain phosphoryla ...... h, and cell cycle progression.

@nl

P1433

Q42793655-37FCE1C3-17BB-4A80-97F8-2959E5B9D529

P1476

Q42793655-B88F2045-A4BA-4016-8686-6411A1983413

P2093

Q42793655-128E8019-6981-4A45-A5E2-4DF4B21C60EA

Q42793655-4474813F-FFAF-42B1-9393-C294BCF510FE

Q42793655-4BA3407C-BE3F-496D-8541-ECEA216C9948

Q42793655-76D0C040-5E82-48EE-8C8B-C81398A007FE

Q42793655-A2D01D78-FA6A-43CB-BE8F-83C2E8EB868D

Q42793655-E7AECA01-0D00-4A2F-824D-733A5B2D3FDE

P2860

Q42793655-02CC8FBF-6AAE-4010-9F03-28990A3E9E06

Q42793655-03038800-2FF4-4B54-9AE5-E4DA16F6A0C5

Q42793655-052D18D3-98B7-46EC-B81E-9BA988A6EEA2

Q42793655-06A5B557-1710-4EB9-A20B-65CE6BA6BC10

Q42793655-07171A0C-5DF9-4127-B431-D494110BB270

Q42793655-09C8D028-5594-4D76-9A11-C52DD205A708

Q42793655-109A3434-C08D-458F-A201-A99E5D6809DC

Q42793655-13BBED4B-5F75-4583-96D2-5589ECCD9F46

Q42793655-1605B85E-1C9D-4E41-853A-EDF8383AE48D

Q42793655-1FB0207E-E5DC-4670-85C8-A6177E113BF8

P304

Q42793655-A3AA412A-5741-430E-ACE8-0290A075C5F3

P31

Q42793655-E4318F08-862F-4743-A989-3A07CE565969

P356

Q42793655-583559B9-13EC-4B4B-9C35-301270F7D64F

P407

Q42793655-9DBCED96-EA93-411E-B22C-E42D50631835

P433

Q42793655-76B90DB6-1D43-4A00-882A-45CCA4E09110

P478

Q42793655-4979EB2F-1C35-4052-840F-D256D8ADA1A0

P577

Q42793655-28AD922F-DE3C-4BDC-ADEC-C527A8F95221

P698

Q42793655-6608405A-120F-4D4F-8EED-9E995C63B7D7

P921

Q42793655-D4AD91AB-CD98-4B4D-8C0C-3F6A851DF488

P932

Q42793655-CC268B70-EDBF-4495-A5B3-4B17F2030C74

P356

P1433

Molecular and Cellular Biology

P1476

mTOR kinase domain phosphoryla ...... h, and cell cycle progression.

@en

P2093

Bilgen Ekim

http://www.w3.org/2001/XMLSchema#string

Brian Magnuson

http://www.w3.org/2001/XMLSchema#string

Diane C Fingar

http://www.w3.org/2001/XMLSchema#string

Edward P Feener

http://www.w3.org/2001/XMLSchema#string

Hugo A Acosta-Jaquez

http://www.w3.org/2001/XMLSchema#string

Jennifer A Keller

http://www.w3.org/2001/XMLSchema#string

P2860

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase

mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex

P304

2787-2801

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/MCB.05437-11

http://www.w3.org/2001/XMLSchema#string

P407

P433

14

http://www.w3.org/2001/XMLSchema#string

P478

31

http://www.w3.org/2001/XMLSchema#string

P577

2011-05-16T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

21576368

http://www.w3.org/2001/XMLSchema#string

P921

phosphorylation

P932

3133410

http://www.w3.org/2001/XMLSchema#string